盐酸替莫普利

Description

Temocapril hydrochloride · CAS 110221-44-8 · C23H29ClN2O5S2. UNII 8G820I95VP.

Identification

CAS Registry Number	110221-44-8
PubChem CID	443873
Molecular formula	C23H29ClN2O5S2
IUPAC name	2-[(2S,6R)-6-[[(2S)-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]-5-oxo-2-thiophen-2-yl-1,4-thiazepan-4-yl]acetic acid;hydrochloride
UNII (FDA)	8G820I95VP

Computed Descriptors

Molecular Weight	513.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	11
Exact Mass	512.1206421
Monoisotopic Mass	512.1206421
Topological Polar Surface Area	149
Heavy Atom Count	33
Formal Charge	0
Complexity	644

Documented Uses

• A class of drugs whose main indications are the treatment of hypertension and heart failure. They exert their hemodynamic effect mainly by inhibiting the renin-angiotensin system. They also modulate sympathetic nervous system activity and increase prostaglandin synthesis. They cause mainly vasodilation and mild natriuresis without affecting heart rate and contractility.
• Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.

Synonyms

temocapril hydrochloride; 110221-44-8; Temocapril HCl; Acecol; CS-622; DTXSID7046914; 8G820I95VP; DTXCID5026914; RefChem:932698; Temocapril (hydrochloride); AC-757; Tox21_112803_1; NCGC00181345-01; CAS-110221-44-8; MFCD00933433; Acecol (TN)

Frequently Asked Questions

What are the CAS number and molecular formula of Temocapril hydrochloride?

CAS 110221-44-8; molecular formula C23H29ClN2O5S2; molecular weight — g/mol.

What other names is Temocapril hydrochloride known by?

temocapril hydrochloride, 110221-44-8, Temocapril HCl, Acecol, CS-622, DTXSID7046914.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.