Tamsulosin

CAS 106133-20-4C20H28N2O5SMW 408.5

Tamsulosin (CAS 106133-20-4) — formula C20H28N2O5S, molecular weight 408.5.

Product Overview

CAS Number	106133-20-4
Molecular Formula	C20H28N2O5S
Molecular Weight	408.5
Melting Point	230
LogP	2.3
Applications	Uses: A selective antagonist at alpha-1A and alpha-1B adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck., THERAP CAT: In treatment of benign prostatic hypertrophy, Methods of Manufacturing: Preparation: K. Imai et al., EP 34432, eidem, US 4703063 (1981, 1987 both to Yamanouchi)., Impurities: 5-[(2R)-2-[bis[2-[(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide, 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide, 2-methoxy-5-[(2R)-2-[(2-phenoxyethyl)amino]propyl[benzenesulfonamide, 2-methoxy-5-[(2R)-2-[[2-(2-methoxyphenoxy)ethyl]amino]propyl]benzenesulfonamide, For more Impurities (Complete) data for Tamsulosin (9 total), please visit the HSDB record page., Formulations, Preparations: Formulations: (AHFS, 2009), Table: Formulations: (AHFS, 2009) [Table#7410]

Applications

Documented applications: Uses: A selective antagonist at alpha-1A and alpha-1B adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck., THERAP CAT: In treatment of benign prostatic hypertrophy, Methods of Manufacturing: Preparation: K. Imai et al., EP 34432, eidem, US 4703063 (1981, 1987 both to Yamanouchi)., Impurities: 5-[(2R)-2-[bis[2-[(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide, 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide, 2-methoxy-5-[(2R)-2-[(2-phenoxyethyl)amino]propyl[benzenesulfonamide, 2-methoxy-5-[(2R)-2-[[2-(2-methoxyphenoxy)ethyl]amino]propyl]benzenesulfonamide, For more Impurities (Complete) data for Tamsulosin (9 total), please visit the HSDB record page., Formulations, Preparations: Formulations: (AHFS, 2009), Table: Formulations: (AHFS, 2009) [Table#7410].

Technical Profile

What this product is

Tamsulosin is a chemical compound with CAS registry number 106133-20-4 and molecular formula C20H28N2O5S (molecular weight 408.5).

Identification

CAS number: 106133-20-4

Its molecular formula C20H28N2O5S comprises 20 C, 28 H, 2 N, 5 O, 1 S atoms.

Also known as: Tamsulosin · 坦索罗辛

Frequently Asked Questions

What is the CAS number of Tamsulosin?

The CAS registry number of Tamsulosin is 106133-20-4.

What is the molecular formula and molecular weight of Tamsulosin?

Molecular formula C20H28N2O5S, molecular weight 408.5.

What other names is Tamsulosin known by?

It is also registered under: Tamsulosin, 坦索罗辛.

What are the documented applications of Tamsulosin?

Recorded applications: Uses: A selective antagonist at alpha-1A and alpha-1B adrenoceptors in the prostate, prostatic capsule, prostatic urethra, and bladder neck., THERAP CAT: In treatment of benign prostatic hypertrophy, Methods of Manufacturing: Preparation: K. Imai et al., EP 34432, eidem, US 4703063 (1981, 1987 both to Yamanouchi)., Impurities: 5-[(2R)-2-[bis[2-[(2-ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide, 5-[(2R)-2-aminopropyl]-2-methoxybenzenesulfonamide, 2-methoxy-5-[(2R)-2-[(2-phenoxyethyl)amino]propyl[benzenesulfonamide, 2-methoxy-5-[(2R)-2-[[2-(2-methoxyphenoxy)ethyl]amino]propyl]benzenesulfonamide, For more Impurities (Complete) data for Tamsulosin (9 total), please visit the HSDB record page., Formulations, Preparations: Formulations: (AHFS, 2009), Table: Formulations: (AHFS, 2009) [Table#7410].

PubChem Public Data

Independent reference data for Tamsulosin (CAS 106133-20-4), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number	106133-20-4
PubChem CID	129211
Molecular formula	C20H28N2O5S
IUPAC name	5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide
UNII (FDA)	G3P28OML5I

Computed descriptors

Molecular Weight	408.5
XLogP3	2.7
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	11
Exact Mass	408.17189317
Monoisotopic Mass	408.17189317
Topological Polar Surface Area	108
Heavy Atom Count	28

Physicochemical values on record

Melting Point	230
Solubility	6.55e-03 g/L
LogP	2.3
LogP	2.2

Documented uses on record

Synonyms and trade names

TAMSULOSIN; 106133-20-4; (R)-5-(2-((2-(2-Ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide; Tamsulosine; Tamsulosina; Tamsulosinum; (-)-Tamsulosin; Tamsulon; 5-[(2R)-2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxybenzenesulfonamide; (r)-(-)-tamsulosin; G3P28OML5I; HIP1402; HGP-0412; HIP-1402; CHEBI:9398; DTXSID3023631

What the public record says

Tamsulosin · CAS 106133-20-4 · C20H28N2O5S. UNII G3P28OML5I. Melting Point: 230; Solubility: 6.55e-03 g/L; LogP: 2.3.

Physical description and handling notes

Source: PubChem / Wikidata; the batch COA governs where values differ.