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Silica Gel

CAS 13778-37-5O2SiMW 60.084

Silica Gel (CAS 13778-37-5) — formula O2Si, molecular weight 60.084; category food additives.

Product Overview

CAS Number13778-37-5
Molecular FormulaO2Si
Molecular Weight60.084
Melting Point3110 °F (NIOSH, 2024)
Boiling Point4046 °F at 760 mmHg (NIOSH, 2024)
ApplicationsUses: CIR ingredient: Silica, Used as a filler in rubber products, paints, animal feeds, pesticides, insulation materials, and cosmetics, [Rom, p. 527] Silica nanoparticle applications include leukemia cell biomarkers, cancer therapy, drug delivery, mechanical polishing, and additives to drugs, cosmetics, printing inks, varnishes, and food, [PMID 21191487] Polycrystalline silicon and silicon dioxide materials are etched in semiconductor manufacturing. [CSH, p. 45], Semiconductor Manufacturing [Category: Industry], Mining [Category: Industry], Cement Producing [Category: Industry], Farming (Feed Additives) [Category: Industry], For silicon dioxide (USEPA, OPP Pesticide Code: 072605 ACTIVE products with label matches., SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., Amorphous silica (such as fumed silica) is incorporated in a variety of food products as anti-caking agents at levels up to 2% by weight. Amorphous silica is also used as an anti-caking agent and as an excipient in pharmaceuticals for various drug and vitamin preparations., According to the different physicochemical properties, the major classes of synthetic amorphous silica are used in a variety of products, e.g. as fillers in the rubber industry, in tire compounds, as free-flow and anti-caking agents in powder materials, and as liquid carriers, particularly in the manufacture of animal feed and agrochemicals, other uses are found in toothpaste additives, silicon rubber, insulation material, liquid systems in coatings, adhesives, plastisol car undercoats, and cosmetics., Bioactive glasses are silica-based, surface-active bone substitutes that have shown good biocompatibility both in bone and in soft tissue and are used in oral and maxillofacial bone augmentation., For more Uses (Complete) data for AMORPHOUS SILICA (18 total), please visit the HSDB record page., Silica sand has been used for many different purposes for many years, its most ancient and principal use throughout history has been in the manufacture of glass. Sands are used in ceramics, foundry, abrasive, hydraulic fracturing applications and many other uses., Refractory silica bricks, in which silica is converted by heat into cristobalite and tridymite are used in sprung arches of open-hearth furnaces, covers of electric furnaces, roofs of glass-tank furnaces, blast pre-heaters and coke and gas ovens., ...Several uses require the material, sand and gravel, to be ground. In some uses (e.g. sandblasting, abrasives), grinding also occurs during the use., Industrial sand sold or used by United States producers in 1994, by major end use -- Glass-making: containers, flat (plate and window), specialty, and fibreglass (un-ground or ground), Foundry: moulding and core, moulding and core facing (ground), and refractory, Metallurgical applications: silicon carbide and flux for metal smelting, Abrasives: blasting, scouring cleansers (ground), sawing and sanding, and chemicals (ground and un-ground), Fillers: rubber, putty, and whole grain fillers, building products, Ceramics: pottery, brick, tile, Filtration: water (municipal, county, local), swimming pools, and others, Petroleum industry: hydraulic fracturing, well packing, and cementing, Recreational: golf courses, baseball, volleyball, play sands, beaches, traction (engine), roofing granules and fillers, and other purposes (ground silica or whole grain)., From table, For more Uses (Complete) data for CRYSTALLINE SILICA (7 total), Use Classification: Chemical Classes -> Inorganic substances, EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Fragrance Ingredients, Food Additives -> ANTICAKING_AGENT -> JECFA Functional Classes, Cosmetics -> Absorbent, Viscosity controlling, Abrasive, Anticaking, Bulking, Opacifying, Industry Uses: Other, Insulators, Abrasives, Heat transferring agent, pH regulating agent, Sealant (barrier), Crystal growth modifiers (nucleating agents), Not Known or Reasonably Ascertainable, Filler, Stabilizing agent, Flow promoter, Hardener, Adsorbent, Surface modifier, Other, Surfactant (surface active agent), Processing aids not otherwise specified, Bleaching agent, Opacifer, Plating agent, Anti-adhesive, cohesive, Intermediates, Polymerization promoter, Dispersing agent, Anti-caking agent, Lubricating agent, CBI, Wetting agent (non-aqueous), Binder, Processing aids, specific to petroleum production, Intermediate, Chelating agent, Solids separation (precipitating) agent, not otherwise specified, Anti-static agent, Pigment, Adhesion, cohesion promoter, Etching agent, Defoamer, Oxidizing agent, Dehydrating agent (desiccant), Anti-slip agent, Plasticizer, Dusting agent, Hydraulic fluids, Absorbent, Corrosion inhibitor, Thickening agent, Ion exchange agent, Catalyst, Soil amendments (fertilizers), Viscosity modifiers, Film former, Consumer Uses: Filler
CategoryEco Materials|Food Processing Aids

Applications

Documented applications: Uses: CIR ingredient: Silica, Used as a filler in rubber products, paints, animal feeds, pesticides, insulation materials, and cosmetics, [Rom, p. 527] Silica nanoparticle applications include leukemia cell biomarkers, cancer therapy, drug delivery, mechanical polishing, and additives to drugs, cosmetics, printing inks, varnishes, and food, [PMID 21191487] Polycrystalline silicon and silicon dioxide materials are etched in semiconductor manufacturing. [CSH, p. 45], Semiconductor Manufacturing [Category: Industry], Mining [Category: Industry], Cement Producing [Category: Industry], Farming (Feed Additives) [Category: Industry], For silicon dioxide (USEPA, OPP Pesticide Code: 072605 ACTIVE products with label matches., SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., Amorphous silica (such as fumed silica) is incorporated in a variety of food products as anti-caking agents at levels up to 2% by weight. Amorphous silica is also used as an anti-caking agent and as an excipient in pharmaceuticals for various drug and vitamin preparations., According to the different physicochemical properties, the major classes of synthetic amorphous silica are used in a variety of products, e.g. as fillers in the rubber industry, in tire compounds, as free-flow and anti-caking agents in powder materials, and as liquid carriers, particularly in the manufacture of animal feed and agrochemicals, other uses are found in toothpaste additives, silicon rubber, insulation material, liquid systems in coatings, adhesives, plastisol car undercoats, and cosmetics., Bioactive glasses are silica-based, surface-active bone substitutes that have shown good biocompatibility both in bone and in soft tissue and are used in oral and maxillofacial bone augmentation., For more Uses (Complete) data for AMORPHOUS SILICA (18 total), please visit the HSDB record page., Silica sand has been used for many different purposes for many years, its most ancient and principal use throughout history has been in the manufacture of glass. Sands are used in ceramics, foundry, abrasive, hydraulic fracturing applications and many other uses., Refractory silica bricks, in which silica is converted by heat into cristobalite and tridymite are used in sprung arches of open-hearth furnaces, covers of electric furnaces, roofs of glass-tank furnaces, blast pre-heaters and coke and gas ovens., ...Several uses require the material, sand and gravel, to be ground. In some uses (e.g. sandblasting, abrasives), grinding also occurs during the use., Industrial sand sold or used by United States producers in 1994, by major end use -- Glass-making: containers, flat (plate and window), specialty, and fibreglass (un-ground or ground), Foundry: moulding and core, moulding and core facing (ground), and refractory, Metallurgical applications: silicon carbide and flux for metal smelting, Abrasives: blasting, scouring cleansers (ground), sawing and sanding, and chemicals (ground and un-ground), Fillers: rubber, putty, and whole grain fillers, building products, Ceramics: pottery, brick, tile, Filtration: water (municipal, county, local), swimming pools, and others, Petroleum industry: hydraulic fracturing, well packing, and cementing, Recreational: golf courses, baseball, volleyball, play sands, beaches, traction (engine), roofing granules and fillers, and other purposes (ground silica or whole grain)., From table, For more Uses (Complete) data for CRYSTALLINE SILICA (7 total), Use Classification: Chemical Classes -> Inorganic substances, EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Fragrance Ingredients, Food Additives -> ANTICAKING_AGENT -> JECFA Functional Classes, Cosmetics -> Absorbent, Viscosity controlling, Abrasive, Anticaking, Bulking, Opacifying, Industry Uses: Other, Insulators, Abrasives, Heat transferring agent, pH regulating agent, Sealant (barrier), Crystal growth modifiers (nucleating agents), Not Known or Reasonably Ascertainable, Filler, Stabilizing agent, Flow promoter, Hardener, Adsorbent, Surface modifier, Other, Surfactant (surface active agent), Processing aids not otherwise specified, Bleaching agent, Opacifer, Plating agent, Anti-adhesive, cohesive, Intermediates, Polymerization promoter, Dispersing agent, Anti-caking agent, Lubricating agent, CBI, Wetting agent (non-aqueous), Binder, Processing aids, specific to petroleum production, Intermediate, Chelating agent, Solids separation (precipitating) agent, not otherwise specified, Anti-static agent, Pigment, Adhesion, cohesion promoter, Etching agent, Defoamer, Oxidizing agent, Dehydrating agent (desiccant), Anti-slip agent, Plasticizer, Dusting agent, Hydraulic fluids, Absorbent, Corrosion inhibitor, Thickening agent, Ion exchange agent, Catalyst, Soil amendments (fertilizers), Viscosity modifiers, Film former, Consumer Uses: Filler.

Technical Profile

What this product is

Silica Gel is a food-grade compound with CAS registry number 13778-37-5 and molecular formula O2Si (molecular weight 60.084), belonging to the food additives segment of chemical raw materials.

Identification

CAS number: 13778-37-5

Its molecular formula O2Si comprises 2 O, 1 Si atoms.

Also known as: Silica Gel · 硅胶

Category: chemical / food additives

Frequently Asked Questions

What is the CAS number of Silica Gel?

The CAS registry number of Silica Gel is 13778-37-5.

What is the molecular formula and molecular weight of Silica Gel?

Molecular formula O2Si, molecular weight 60.084.

What other names is Silica Gel known by?

It is also registered under: Silica Gel, 硅胶.

What are the documented applications of Silica Gel?

Recorded applications: Uses: CIR ingredient: Silica, Used as a filler in rubber products, paints, animal feeds, pesticides, insulation materials, and cosmetics, [Rom, p. 527] Silica nanoparticle applications include leukemia cell biomarkers, cancer therapy, drug delivery, mechanical polishing, and additives to drugs, cosmetics, printing inks, varnishes, and food, [PMID 21191487] Polycrystalline silicon and silicon dioxide materials are etched in semiconductor manufacturing. [CSH, p. 45], Semiconductor Manufacturing [Category: Industry], Mining [Category: Industry], Cement Producing [Category: Industry], Farming (Feed Additives) [Category: Industry], For silicon dioxide (USEPA, OPP Pesticide Code: 072605 ACTIVE products with label matches., SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., Amorphous silica (such as fumed silica) is incorporated in a variety of food products as anti-caking agents at levels up to 2% by weight. Amorphous silica is also used as an anti-caking agent and as an excipient in pharmaceuticals for various drug and vitamin preparations., According to the different physicochemical properties, the major classes of synthetic amorphous silica are used in a variety of products, e.g. as fillers in the rubber industry, in tire compounds, as free-flow and anti-caking agents in powder materials, and as liquid carriers, particularly in the manufacture of animal feed and agrochemicals, other uses are found in toothpaste additives, silicon rubber, insulation material, liquid systems in coatings, adhesives, plastisol car undercoats, and cosmetics., Bioactive glasses are silica-based, surface-active bone substitutes that have shown good biocompatibility both in bone and in soft tissue and are used in oral and maxillofacial bone augmentation., For more Uses (Complete) data for AMORPHOUS SILICA (18 total), please visit the HSDB record page., Silica sand has been used for many different purposes for many years, its most ancient and principal use throughout history has been in the manufacture of glass. Sands are used in ceramics, foundry, abrasive, hydraulic fracturing applications and many other uses., Refractory silica bricks, in which silica is converted by heat into cristobalite and tridymite are used in sprung arches of open-hearth furnaces, covers of electric furnaces, roofs of glass-tank furnaces, blast pre-heaters and coke and gas ovens., ...Several uses require the material, sand and gravel, to be ground. In some uses (e.g. sandblasting, abrasives), grinding also occurs during the use., Industrial sand sold or used by United States producers in 1994, by major end use -- Glass-making: containers, flat (plate and window), specialty, and fibreglass (un-ground or ground), Foundry: moulding and core, moulding and core facing (ground), and refractory, Metallurgical applications: silicon carbide and flux for metal smelting, Abrasives: blasting, scouring cleansers (ground), sawing and sanding, and chemicals (ground and un-ground), Fillers: rubber, putty, and whole grain fillers, building products, Ceramics: pottery, brick, tile, Filtration: water (municipal, county, local), swimming pools, and others, Petroleum industry: hydraulic fracturing, well packing, and cementing, Recreational: golf courses, baseball, volleyball, play sands, beaches, traction (engine), roofing granules and fillers, and other purposes (ground silica or whole grain)., From table, For more Uses (Complete) data for CRYSTALLINE SILICA (7 total), Use Classification: Chemical Classes -> Inorganic substances, EPA Safer Chemical Functional Use Classes -> Processing Aids and Additives, Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern, Fragrance Ingredients, Food Additives -> ANTICAKING_AGENT -> JECFA Functional Classes, Cosmetics -> Absorbent, Viscosity controlling, Abrasive, Anticaking, Bulking, Opacifying, Industry Uses: Other, Insulators, Abrasives, Heat transferring agent, pH regulating agent, Sealant (barrier), Crystal growth modifiers (nucleating agents), Not Known or Reasonably Ascertainable, Filler, Stabilizing agent, Flow promoter, Hardener, Adsorbent, Surface modifier, Other, Surfactant (surface active agent), Processing aids not otherwise specified, Bleaching agent, Opacifer, Plating agent, Anti-adhesive, cohesive, Intermediates, Polymerization promoter, Dispersing agent, Anti-caking agent, Lubricating agent, CBI, Wetting agent (non-aqueous), Binder, Processing aids, specific to petroleum production, Intermediate, Chelating agent, Solids separation (precipitating) agent, not otherwise specified, Anti-static agent, Pigment, Adhesion, cohesion promoter, Etching agent, Defoamer, Oxidizing agent, Dehydrating agent (desiccant), Anti-slip agent, Plasticizer, Dusting agent, Hydraulic fluids, Absorbent, Corrosion inhibitor, Thickening agent, Ion exchange agent, Catalyst, Soil amendments (fertilizers), Viscosity modifiers, Film former, Consumer Uses: Filler.

Which category does Silica Gel belong to?

Category: Eco Materials / Food Processing Aids.

PubChem Public Data

Independent reference data for Silica Gel (CAS 13778-37-5), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number13778-37-5
PubChem CID24261
Molecular formulaO2Si
IUPAC namedioxosilane
UNII (FDA)ETJ7Z6XBU4

Computed descriptors

Molecular Weight60.084
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count2
Rotatable Bond Count0
Exact Mass59.966755773
Monoisotopic Mass59.966755773
Topological Polar Surface Area34.1
Heavy Atom Count3

Physicochemical values on record

Boiling Point4046 °F at 760 mmHg (NIOSH, 2024)
Boiling Point4046 °F
Boiling Point2230 °C
Boiling Point2950 °C @760 [mm Hg]
Melting Point3110 °F (NIOSH, 2024)
Melting Point3110 °F
Melting Point1710 °C
Melting Point1716 - 1736 °C
Melting Point1713 °C
Melting Point1722 °C

Documented uses on record

    Semiconductor Manufacturing [Category: Industry]Cement Producing [Category: Industry]

    Synonyms and trade names

    SILICON DIOXIDE; Silica; Dioxosilane; 7631-86-9; Silicic anhydride; Diatomaceous silica; Wessalon; Zorbax sil; Silica, amorphous; Silica, colloidal; Sillikolloid; Acticel; Carplex; Extrusil; Porasil; Santocel

    Regulatory listings held on file

    Regulatory & Food ContactFDA Substance added to food: ANTICAKING AGENT OR FREE-FLOW AGENT, ANTIOXIDANT, COLOR OR COLORING ADJUNCT, DRY
    FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS
    FDA Inventory of Effective Food Contact Substance (FCS) Noti: FCS
    ANTICAKING_AGENT: Food Additives
    ANTICAKING AGENT OR FREE-FLOW AGENT, ANTIOXIDANT, COLOR OR COLORING ADJUNCT, DRYING AGENT, EMULSIFIER OR EMULS
    Use in a variety of foods and food-packing materials
    GHS notification summary35% (889 / 2540)

    GHS hazard classification

    GHS notification summary35% (889 / 2540)
    Reported hazard statementsH315 (56.3%), H319 (56.3%), H335 (56.3%), H350 (12.6%), H372 (46%), H373 (29.4%), H341, H320

    Reported as not meeting GHS hazard criteria by 7724 of 9127 companies

    Aggregated GHS information provided per 9127 reports by companies from 60 notifications to the ECHA C&L Inventory.

    What the public record says

    Fused Silica · CAS 13778-37-5 · O2Si. UNII ETJ7Z6XBU4. Boiling Point: 4046 °F at 760 mmHg (NIOSH, 2024); Boiling Point: 4046 °F; Boiling Point: 2230 °C.

    Physical description and handling notes

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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中文页面: 硅胶

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