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(R)-(+)-沙利度胺

CAS 2614-06-4C13H10N2O4MW 258.23

(R)-(+)-沙利度胺(CAS 2614-06-4):分子式 C13H10N2O4、分子量 258.23。

产品概览

CAS号2614-06-4
分子式C13H10N2O4
分子量258.23
熔点516 to 520 °F (NTP, 1992)
LogP0.33
应用领域Uses: MEDICATION、Angiogenesis Inhibitors、Immunosuppressive Agents、Leprostatic Agents、Teratogens、For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma.、Methods of Manufacturing: Preparation: United Kingdom patent 768821 (1957 to Chemie Grunenthal)、Formulations、Preparations: Thalidomide was first marketed in Germany 1957 under the name Contergan、in the UK in 1958 as Distaval、and finally at least under 35 further names worldwide.、Table: Thalidomide Preparations [Table#4648]、General Manufacturing Information: Thalidomide is commercially available as a 1:1 racemic mixture of the 2 enantiomers with a net optical rotation of zero.

应用领域

登记用途:Uses: MEDICATION、Angiogenesis Inhibitors、Immunosuppressive Agents、Leprostatic Agents、Teratogens、For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma.、Methods of Manufacturing: Preparation: United Kingdom patent 768821 (1957 to Chemie Grunenthal)、Formulations、Preparations: Thalidomide was first marketed in Germany 1957 under the name Contergan、in the UK in 1958 as Distaval、and finally at least under 35 further names worldwide.、Table: Thalidomide Preparations [Table#4648]、General Manufacturing Information: Thalidomide is commercially available as a 1:1 racemic mixture of the 2 enantiomers with a net optical rotation of zero.。

技术档案

这个产品是什么

(R)-(+)-沙利度胺 是一种化工化合物,登记 CAS 号为 2614-06-4,分子式 C13H10N2O4(分子量 258.23)。

识别信息

登记 CAS 号:2614-06-4

其分子式 C13H10N2O4 由 13 个碳、10 个氢、2 个氮、4 个氧 组成。

别名/同义词:(R)-(+)-沙利度胺 · (R)-(+)-THALIDOMIDE

常见问题

(R)-(+)-沙利度胺 的 CAS 号是多少?

(R)-(+)-沙利度胺 的 CAS 登记号为 2614-06-4。

(R)-(+)-沙利度胺 的分子式与分子量是多少?

分子式 C13H10N2O4,分子量 258.23。

(R)-(+)-沙利度胺 还有哪些别名?

别名/同义词:(R)-(+)-沙利度胺、(R)-(+)-THALIDOMIDE。

(R)-(+)-沙利度胺 的登记用途是什么?

登记用途:Uses: MEDICATION、Angiogenesis Inhibitors、Immunosuppressive Agents、Leprostatic Agents、Teratogens、For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma.、Methods of Manufacturing: Preparation: United Kingdom patent 768821 (1957 to Chemie Grunenthal)、Formulations、Preparations: Thalidomide was first marketed in Germany 1957 under the name Contergan、in the UK in 1958 as Distaval、and finally at least under 35 further names worldwide.、Table: Thalidomide Preparations [Table#4648]、General Manufacturing Information: Thalidomide is commercially available as a 1:1 racemic mixture of the 2 enantiomers with a net optical rotation of zero.。

PubChem 公开数据

(R)-(+)-沙利度胺(CAS 2614-06-4)的独立参考数据,整理自公开化学数据库。

各数据库的登记标识

CAS 号2614-06-4
PubChem CID5426
分子式C13H10N2O4
IUPAC 名称2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione
UNII(FDA)4Z8R6ORS6L

计算分子描述符

Molecular Weight258.23
XLogP30.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count1
Exact Mass258.06405680
Monoisotopic Mass258.06405680
Topological Polar Surface Area83.6
Heavy Atom Count19

在册的理化数值

Melting Point516 to 520 °F (NTP, 1992)
Melting Point270
Melting Point270 °C
Solubility545
Solubility2.55e+00 g/L
LogP0.33
LogPlog Kow = 0.33
LogP0.3
LogP0.49

同义词与商品名

thalidomide; 50-35-1; Thalomid; Contergan; Pantosediv; Distaval; Softenon; Kevadon; Psychotablets; Algosediv; Calmorex; Neosedyn; Profarmil; Quetimid; Sedisperil; Imidene

GHS 危害分类

已通报的危害声明H302 (88.2%), H360 (92.1%)

公开数据库对它的描述

(R)-(+)-沙利度胺 · CAS 2614-06-4 · C13H10N2O4. UNII 4Z8R6ORS6L. Melting Point: 516 to 520 °F (NTP, 1992); Melting Point: 270; Melting Point: 270 °C.

数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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