(R)-(+)-沙利度胺(CAS 2614-06-4):分子式 C13H10N2O4、分子量 258.23。
| CAS号 | 2614-06-4 |
|---|---|
| 分子式 | C13H10N2O4 |
| 分子量 | 258.23 |
| 熔点 | 516 to 520 °F (NTP, 1992) |
| LogP | 0.33 |
| 应用领域 | Uses: MEDICATION、Angiogenesis Inhibitors、Immunosuppressive Agents、Leprostatic Agents、Teratogens、For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma.、Methods of Manufacturing: Preparation: United Kingdom patent 768821 (1957 to Chemie Grunenthal)、Formulations、Preparations: Thalidomide was first marketed in Germany 1957 under the name Contergan、in the UK in 1958 as Distaval、and finally at least under 35 further names worldwide.、Table: Thalidomide Preparations [Table#4648]、General Manufacturing Information: Thalidomide is commercially available as a 1:1 racemic mixture of the 2 enantiomers with a net optical rotation of zero. |
登记用途:Uses: MEDICATION、Angiogenesis Inhibitors、Immunosuppressive Agents、Leprostatic Agents、Teratogens、For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma.、Methods of Manufacturing: Preparation: United Kingdom patent 768821 (1957 to Chemie Grunenthal)、Formulations、Preparations: Thalidomide was first marketed in Germany 1957 under the name Contergan、in the UK in 1958 as Distaval、and finally at least under 35 further names worldwide.、Table: Thalidomide Preparations [Table#4648]、General Manufacturing Information: Thalidomide is commercially available as a 1:1 racemic mixture of the 2 enantiomers with a net optical rotation of zero.。
(R)-(+)-沙利度胺 是一种化工化合物,登记 CAS 号为 2614-06-4,分子式 C13H10N2O4(分子量 258.23)。
登记 CAS 号:2614-06-4
其分子式 C13H10N2O4 由 13 个碳、10 个氢、2 个氮、4 个氧 组成。
别名/同义词:(R)-(+)-沙利度胺 · (R)-(+)-THALIDOMIDE
(R)-(+)-沙利度胺 的 CAS 登记号为 2614-06-4。
分子式 C13H10N2O4,分子量 258.23。
别名/同义词:(R)-(+)-沙利度胺、(R)-(+)-THALIDOMIDE。
登记用途:Uses: MEDICATION、Angiogenesis Inhibitors、Immunosuppressive Agents、Leprostatic Agents、Teratogens、For the acute treatment of the cutaneous manifestations of moderate to severe erythema nodosum leprosum (ENL). Also for use as maintenance therapy for prevention and suppression of the cutaneous manifestations of ENL recurrence. Used to treat multiple myeloma.、Methods of Manufacturing: Preparation: United Kingdom patent 768821 (1957 to Chemie Grunenthal)、Formulations、Preparations: Thalidomide was first marketed in Germany 1957 under the name Contergan、in the UK in 1958 as Distaval、and finally at least under 35 further names worldwide.、Table: Thalidomide Preparations [Table#4648]、General Manufacturing Information: Thalidomide is commercially available as a 1:1 racemic mixture of the 2 enantiomers with a net optical rotation of zero.。
(R)-(+)-沙利度胺(CAS 2614-06-4)的独立参考数据,整理自公开化学数据库。
| CAS 号 | 2614-06-4 |
|---|---|
| PubChem CID | 5426 |
| 分子式 | C13H10N2O4 |
| IUPAC 名称 | 2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione |
| UNII(FDA) | 4Z8R6ORS6L |
| Molecular Weight | 258.23 |
|---|---|
| XLogP3 | 0.3 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 1 |
| Exact Mass | 258.06405680 |
| Monoisotopic Mass | 258.06405680 |
| Topological Polar Surface Area | 83.6 |
| Heavy Atom Count | 19 |
| Melting Point | 516 to 520 °F (NTP, 1992) |
|---|---|
| Melting Point | 270 |
| Melting Point | 270 °C |
| Solubility | 545 |
| Solubility | 2.55e+00 g/L |
| LogP | 0.33 |
| LogP | log Kow = 0.33 |
| LogP | 0.3 |
| LogP | 0.49 |
thalidomide; 50-35-1; Thalomid; Contergan; Pantosediv; Distaval; Softenon; Kevadon; Psychotablets; Algosediv; Calmorex; Neosedyn; Profarmil; Quetimid; Sedisperil; Imidene
| 已通报的危害声明 | H302 (88.2%), H360 (92.1%) |
|---|
(R)-(+)-沙利度胺 · CAS 2614-06-4 · C13H10N2O4. UNII 4Z8R6ORS6L. Melting Point: 516 to 520 °F (NTP, 1992); Melting Point: 270; Melting Point: 270 °C.
数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。
English page: (R)-(+)-THALIDOMIDE