阿托品杂质27（CAS 13269-35-7）：分子式 C17H23NO3、分子量 289.4。
| CAS号 | 13269-35-7 |
|---|---|
| 分子式 | C17H23NO3 |
| 分子量 | 289.4 |
| 熔点 | 106 °C |
| LogP | 1.8 |
| 应用领域 | Uses: Hyoscyamine is a plant toxin found in certain plants of the Solanaceae family、including henbane (Hyoscyamus niger)、mandrake (Mandragora officinarum)、jimsonweed (Datura stramonium)、and deadly nightshade (Atropa belladonna). It is used as a drug to provide symptomatic relief to various gastrointestinal disorders including spasms、peptic ulcers、irritable bowel syndrome、pancreatitis、colic and cystitis. It has also been used to relieve some heart problems、control some of the symptoms of Parkinson's disease、as well as for control of respiratory secretions in palliative care.(L1255)、Hyoscyamine is a plant toxin found in certain plants of the Solanaceae family、General Manufacturing Information: THE DEXTRO & LEVO ISOMERS DIFFER MARKEDLY IN POTENCY AT THERAPEUTIC CONCENTRATIONS、BOTH CENTRALLY & PERIPHERALLY. BOTH ISOMERS APPEAR TO HAVE EQUAL POTENCY AT TOXIC CONCENTRATIONS、HOWEVER.、LIVER HOMOGENATES OF RABBITS CONTAINING HYOSCYAMINE ACYLHYDROLASE HYDROLYZED HYOSCYAMINE TO TROPINE AND (-)-TROPIC ACID BUT DID NOT CLEAVE (+)-HYOSCYAMINE. BECAUSE OF THE STEREOSPECIFICITY OF THIS ENZYME、THE HYOSCYAMINE COMPONENT OF (+)-HYOSCYAMINE PREPN OBTAINED CHEMICALLY COULD BE DETECTED AND THE DEXTROROTATORY OPTICAL ANTIPODE COULD BE PREPARED IN THE PURE FORM. |
登记用途：Uses: Hyoscyamine is a plant toxin found in certain plants of the Solanaceae family、including henbane (Hyoscyamus niger)、mandrake (Mandragora officinarum)、jimsonweed (Datura stramonium)、and deadly nightshade (Atropa belladonna). It is used as a drug to provide symptomatic relief to various gastrointestinal disorders including spasms、peptic ulcers、irritable bowel syndrome、pancreatitis、colic and cystitis. It has also been used to relieve some heart problems、control some of the symptoms of Parkinson's disease、as well as for control of respiratory secretions in palliative care.(L1255)、Hyoscyamine is a plant toxin found in certain plants of the Solanaceae family、General Manufacturing Information: THE DEXTRO & LEVO ISOMERS DIFFER MARKEDLY IN POTENCY AT THERAPEUTIC CONCENTRATIONS、BOTH CENTRALLY & PERIPHERALLY. BOTH ISOMERS APPEAR TO HAVE EQUAL POTENCY AT TOXIC CONCENTRATIONS、HOWEVER.、LIVER HOMOGENATES OF RABBITS CONTAINING HYOSCYAMINE ACYLHYDROLASE HYDROLYZED HYOSCYAMINE TO TROPINE AND (-)-TROPIC ACID BUT DID NOT CLEAVE (+)-HYOSCYAMINE. BECAUSE OF THE STEREOSPECIFICITY OF THIS ENZYME、THE HYOSCYAMINE COMPONENT OF (+)-HYOSCYAMINE PREPN OBTAINED CHEMICALLY COULD BE DETECTED AND THE DEXTROROTATORY OPTICAL ANTIPODE COULD BE PREPARED IN THE PURE FORM.。
阿托品杂质27 是一种化工化合物，登记 CAS 号为 13269-35-7，分子式 C17H23NO3（分子量 289.4）。
登记 CAS 号：13269-35-7
其分子式 C17H23NO3 由 17 个碳、23 个氢、1 个氮、3 个氧 组成。
别名/同义词：阿托品杂质27 · R-(+)-Hyoscyamine
阿托品杂质27 的 CAS 登记号为 13269-35-7。
分子式 C17H23NO3，分子量 289.4。
别名/同义词：阿托品杂质27、R-(+)-Hyoscyamine。
登记用途：Uses: Hyoscyamine is a plant toxin found in certain plants of the Solanaceae family、including henbane (Hyoscyamus niger)、mandrake (Mandragora officinarum)、jimsonweed (Datura stramonium)、and deadly nightshade (Atropa belladonna). It is used as a drug to provide symptomatic relief to various gastrointestinal disorders including spasms、peptic ulcers、irritable bowel syndrome、pancreatitis、colic and cystitis. It has also been used to relieve some heart problems、control some of the symptoms of Parkinson's disease、as well as for control of respiratory secretions in palliative care.(L1255)、Hyoscyamine is a plant toxin found in certain plants of the Solanaceae family、General Manufacturing Information: THE DEXTRO & LEVO ISOMERS DIFFER MARKEDLY IN POTENCY AT THERAPEUTIC CONCENTRATIONS、BOTH CENTRALLY & PERIPHERALLY. BOTH ISOMERS APPEAR TO HAVE EQUAL POTENCY AT TOXIC CONCENTRATIONS、HOWEVER.、LIVER HOMOGENATES OF RABBITS CONTAINING HYOSCYAMINE ACYLHYDROLASE HYDROLYZED HYOSCYAMINE TO TROPINE AND (-)-TROPIC ACID BUT DID NOT CLEAVE (+)-HYOSCYAMINE. BECAUSE OF THE STEREOSPECIFICITY OF THIS ENZYME、THE HYOSCYAMINE COMPONENT OF (+)-HYOSCYAMINE PREPN OBTAINED CHEMICALLY COULD BE DETECTED AND THE DEXTROROTATORY OPTICAL ANTIPODE COULD BE PREPARED IN THE PURE FORM.。
阿托品杂质27（CAS 13269-35-7）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 13269-35-7 |
|---|---|
| PubChem CID | 637577 |
| 分子式 | C17H23NO3 |
| IUPAC 名称 | [(1S,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2R)-3-hydroxy-2-phenylpropanoate |
| UNII（FDA） | V3203SI72M |
| Molecular Weight | 289.4 |
|---|---|
| XLogP3 | 1.8 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 5 |
| Exact Mass | 289.16779360 |
| Monoisotopic Mass | 289.16779360 |
| Topological Polar Surface Area | 49.8 |
| Heavy Atom Count | 21 |
| Melting Point | 106 °C |
|---|
RefChem:1048825; ((1S,5R)-8-Methyl-8-Azabicyclo(3.2.1)Octan-3-Yl) (2R)-3-Hydroxy-2-Phenylpropanoate; d-hyoscyamine; (+)-HYOSCYAMINE; 13269-35-7; (+)-Atropine; (R)-atropine; Hyoscyamine, (+)-; CHEMBL3084476; V3203SI72M; [(1R,5S)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] (2R)-3-hydroxy-2-phenylpropanoate; tropan-3alpha-yl (2R)-3-hydroxy-2-phenylpropanoate; (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2R)-3-hydroxy-2-phenylpropanoate; R-(+)-Hyoscyamine; Atropine CRS; Hyoscyamine (D)-
阿托品杂质27 · CAS 13269-35-7 · C17H23NO3. UNII V3203SI72M. Melting Point: 106 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: R-(+)-Hyoscyamine