Proteins, thaumatins (CAS 428847-42-1) — formula C19H29N3O3S, molecular weight 379.5; category chemical.
| CAS Number | 428847-42-1 |
|---|---|
| Molecular Formula | C19H29N3O3S |
| Molecular Weight | 379.5 |
| LogP | 2.4 |
| Applications | Uses: POTENTIAL LOW-CALORIE SWEETENER, Use Classification: Food Additives -> FLAVOUR_ENHANCER, SWEETENER -> JECFA Functional Classes, Methods of Manufacturing: EXTRACTION OF THAUMATIN FROM THAUMATOCOCCUS DANIELLI: J HIGGINBOTHAM, US PATENT NUMBER 4, 011, 206 (1976 TO TATE AND LYLE, LTD). CT VERRIPS, EUROPEAN PATENT APPL 54, 330 AND 54, 331 (BOTH 1982 TO UNILEVER)., General Manufacturing Information: COMPRISED OF TWO ELECTROPHORETIC SPECIES, THAUMATINS I AND II, ONE OF WHICH APPEARS TO BE A PARTIALLY DEAMINATED FORM OF THE OTHER. ... THE PROTEIN CONSISTS OF A SINGLE POLYPEPTIDE CHAIN OF 207 RESIDUES, FIVE SETS OF TRIPEPTIDES ARE IDENTICAL WITH TRIPEPTIDES IN MONELLIN., Thaumatin was one of the sweetening agents studied & found to be low in cariogenic action. No deleterious effect of its use has been found., Various maturation forms of the plant protein thaumatin were expressed in yeast, using a promoter fragment of the glyceraldehyde-3P-dehydrogenase (GAPDH) gene. Nucleotide sequence analysis of 843 nucleotide GAPDH promoter fragment revealed a characteristic structure with 2 regions of dyad symmetry containing translational starts of GAPDH and a putative 38 amino acid peptide. |
| Category | Sweeteners |
Documented applications: Uses: POTENTIAL LOW-CALORIE SWEETENER, Use Classification: Food Additives -> FLAVOUR_ENHANCER, SWEETENER -> JECFA Functional Classes, Methods of Manufacturing: EXTRACTION OF THAUMATIN FROM THAUMATOCOCCUS DANIELLI: J HIGGINBOTHAM, US PATENT NUMBER 4, 011, 206 (1976 TO TATE AND LYLE, LTD). CT VERRIPS, EUROPEAN PATENT APPL 54, 330 AND 54, 331 (BOTH 1982 TO UNILEVER)., General Manufacturing Information: COMPRISED OF TWO ELECTROPHORETIC SPECIES, THAUMATINS I AND II, ONE OF WHICH APPEARS TO BE A PARTIALLY DEAMINATED FORM OF THE OTHER. ... THE PROTEIN CONSISTS OF A SINGLE POLYPEPTIDE CHAIN OF 207 RESIDUES, FIVE SETS OF TRIPEPTIDES ARE IDENTICAL WITH TRIPEPTIDES IN MONELLIN., Thaumatin was one of the sweetening agents studied & found to be low in cariogenic action. No deleterious effect of its use has been found., Various maturation forms of the plant protein thaumatin were expressed in yeast, using a promoter fragment of the glyceraldehyde-3P-dehydrogenase (GAPDH) gene. Nucleotide sequence analysis of 843 nucleotide GAPDH promoter fragment revealed a characteristic structure with 2 regions of dyad symmetry containing translational starts of GAPDH and a putative 38 amino acid peptide..
Proteins, thaumatins is a chemical compound with CAS registry number 428847-42-1 and molecular formula C19H29N3O3S (molecular weight 379.5), belonging to the chemical segment of chemical raw materials.
CAS number: 428847-42-1
Its molecular formula C19H29N3O3S comprises 19 C, 29 H, 3 N, 3 O, 1 S atoms.
Also known as: Proteins, thaumatins · 蛋白质、索马甜 · Thaumatin
Category: chemical
The CAS registry number of Proteins, thaumatins is 428847-42-1.
Molecular formula C19H29N3O3S, molecular weight 379.5.
It is also registered under: Proteins, thaumatins, 蛋白质、索马甜, Thaumatin.
Recorded applications: Uses: POTENTIAL LOW-CALORIE SWEETENER, Use Classification: Food Additives -> FLAVOUR_ENHANCER, SWEETENER -> JECFA Functional Classes, Methods of Manufacturing: EXTRACTION OF THAUMATIN FROM THAUMATOCOCCUS DANIELLI: J HIGGINBOTHAM, US PATENT NUMBER 4, 011, 206 (1976 TO TATE AND LYLE, LTD). CT VERRIPS, EUROPEAN PATENT APPL 54, 330 AND 54, 331 (BOTH 1982 TO UNILEVER)., General Manufacturing Information: COMPRISED OF TWO ELECTROPHORETIC SPECIES, THAUMATINS I AND II, ONE OF WHICH APPEARS TO BE A PARTIALLY DEAMINATED FORM OF THE OTHER. ... THE PROTEIN CONSISTS OF A SINGLE POLYPEPTIDE CHAIN OF 207 RESIDUES, FIVE SETS OF TRIPEPTIDES ARE IDENTICAL WITH TRIPEPTIDES IN MONELLIN., Thaumatin was one of the sweetening agents studied & found to be low in cariogenic action. No deleterious effect of its use has been found., Various maturation forms of the plant protein thaumatin were expressed in yeast, using a promoter fragment of the glyceraldehyde-3P-dehydrogenase (GAPDH) gene. Nucleotide sequence analysis of 843 nucleotide GAPDH promoter fragment revealed a characteristic structure with 2 regions of dyad symmetry containing translational starts of GAPDH and a putative 38 amino acid peptide..
Category: Sweeteners.
Independent reference data for Proteins, thaumatins (CAS 428847-42-1), compiled from public chemistry databases.
| CAS Registry Number | 428847-42-1 |
|---|---|
| PubChem CID | 1151816 |
| Molecular formula | C19H29N3O3S |
| IUPAC name | N-[4-(4-cycloheptylpiperazin-1-yl)sulfonylphenyl]acetamide |
| UNII (FDA) | KNC9Q0EE6G |
| FEMA number | 3732 |
| Molecular Weight | 379.5 |
|---|---|
| XLogP3 | 2.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 4 |
| Exact Mass | 379.19296297 |
| Monoisotopic Mass | 379.19296297 |
| Topological Polar Surface Area | 78.1 |
| Heavy Atom Count | 26 |
N-[4-(4-cycloheptylpiperazine-1-sulfonyl)phenyl]acetamide; Proteins, thaumatins; N-(4-(4-cycloheptylpiperazine-1-sulfonyl)phenyl)acetamide; Neo san maruku ag; Neo san maruku dc; Thaumatin [BAN]; Sansweet t 147; RefChem:897602; KNC9Q0EE6G; FEMA No. 3732; INS NO.957; HSDB 3927; INS-957; DTXSID101018112; EINECS 258-822-2; E-957
| Regulatory & Food Contact | FDA Substance added to food: FLAVORING AGENT OR ADJUVANT FLAVOUR_ENHANCER; SWEETENER: Food Additives At low levels can alter the perception of sweetness and alter the perception of various flavor characteristics Scientific procedures FDA has no questions (in PDF) Nomad Bioscience GmbH |
|---|---|
| GHS notification summary | 51.3% (77 / 150) |
| GHS notification summary | 51.3% (77 / 150) |
|---|---|
| Reported hazard statements | H334 (46.7%), H335 (12%) |
This chemical does not meet GHS hazard criteria for 51.3% (77 of 150) of all reports.
H334 (46.7%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]
Thaumatin · CAS 428847-42-1 · C19H29N3O3S. UNII KNC9Q0EE6G.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 蛋白质、索马甜