Profenofos

Description

Profenofos · CAS 41198-08-7 · C11H15BrClO3PS. UNII 7J04O7BS4W. Boiling Point: 100 °C @ 1.35X10-2 mm Hg; Solubility: In water, 28 mg/l @ 25 °C; Density: 1.455 @ 20 °C.

Identification

CAS Registry Number	41198-08-7
PubChem CID	38779
Molecular formula	C11H15BrClO3PS
IUPAC name	4-bromo-2-chloro-1-[ethoxy(propylsulfanyl)phosphoryl]oxybenzene
UNII (FDA)	7J04O7BS4W

Computed Descriptors

Molecular Weight	373.63
XLogP3	4.7
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	7
Exact Mass	371.93514
Monoisotopic Mass	371.93514
Topological Polar Surface Area	60.8
Heavy Atom Count	18
Formal Charge	0

Physical & Chemical Properties

Boiling Point	100 °C @ 1.35X10-2 mm Hg
Solubility	In water, 28 mg/l @ 25 °C
Density	1.455 @ 20 °C
Vapor Pressure	0.0000009 [mmHg]
Vapor Pressure	9.00X10-7 mm Hg @ 25 °C
LogP	log Kow = 4.68
LogP	4.44
Collision Cross Section	166.64 Ų [M+H]+
Collision Cross Section	182.33 Ų [M+Na]+

Physical description & handling notes

• Profenofos is a pale yellow liquid with garlic-like odor. Corrosive. Used as an insecticide.
• Pale yellow or amber liquid with an odor like garlic; [HSDB]
• Pale yellow liquid
• Amber color, oily liquid
• Garlic-like
• Readily miscible with most organic solvents.

GHS Hazard Classification

Reported hazard statements	H302, H312, H332, H400, H410, H310 (33%), H311 (25%), H317 (60.7%)

Documented Uses

• Used as insecticide and acaricide for cotton and vegetables; [Merck Index] Only used on cotton in the US; [Reference #1]
• Control of insects (particularly Lepidopetera) and mites.
• o-Chlorophenol + phosphorus oxychloride + n-propyl mercaptan + ethanol (ring bromination/dehydrochlorination/dehydrochlorination/dehydrochlorination)
• On avg, approx 775,000 lbs of profenofos are applied to 5% of the est 13.8 million acres of cotton grown annually in the USA.
• ... The levels of profenofos in whole blood, urine, and gastric contents were 1200 ng, 350 ng, and 3.35 mg/mL, respectively.
• Rats rapidly excrete 14C-profenofos after oral admin. The predominant metabolic pathway involves stepwise dealkylation & hydrolysis, followed by conjugation.

Synonyms

PROFENOFOS; 41198-08-7; Curacron; Selecron; Profenophos; O-(4-Bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate; CGA 15324; DTXSID3032464; Phosphorothioic acid, O-(4-bromo-2-chlorophenyl) O-ethyl S-propyl ester; 7J04O7BS4W; CGA-15324; DTXCID1012464; CHEBI:38845; OMS-2004; (RS)-(O-4-BROMO-2-CHLOROPHENYL O-ETHYL S-PROPYL PHOSPHOROTHIOATE); RefChem:868567

Frequently Asked Questions

What are the CAS number and molecular formula of Profenofos?

CAS 41198-08-7; molecular formula C11H15BrClO3PS; molecular weight — g/mol.

What other names is Profenofos known by?

PROFENOFOS, 41198-08-7, Curacron, Selecron, Profenophos, O-(4-Bromo-2-chlorophenyl) O-ethyl S-propyl phosphorothioate.

Is Profenofos classified as hazardous?

Hazard statements reported: H302, H312, H332, H400, H410.

What are the key physical properties of Profenofos?

Boiling Point: 100 °C @ 1.35X10-2 mm Hg; Solubility: In water, 28 mg/l @ 25 °C; Density: 1.455 @ 20 °C; Vapor Pressure: 0.0000009 [mmHg].

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.