普兰林肽

Description

Pramlintide · CAS 151126-32-8 · C171H267N51O53S2. UNII D3FM8FA78T.

Identification

CAS Registry Number	151126-32-8
PubChem CID	70691388
Molecular formula	C171H267N51O53S2
UNII (FDA)	D3FM8FA78T

Computed Descriptors

Molecular Weight	3949
XLogP3	-15.7
Hydrogen Bond Donor Count	56
Hydrogen Bond Acceptor Count	59
Rotatable Bond Count	110
Exact Mass	3947.9240297
Monoisotopic Mass	3946.9206749
Topological Polar Surface Area	1740
Heavy Atom Count	277
Formal Charge	0

Documented Uses

• For the treatment of type 1 and type 2 diabetes mellitus as an adjunct to preprandial insulin therapy in patients without adequate glycemic control of insulin therapy.
• Pramlintide is a recombinant DNA produced polypeptide analogue of human amylin that is used in combination with insulin in the therapy of diabetes. Pramlintide has not been associated with serum enzyme elevations during therapy or with instances of clinically apparent liver injury.
• Breast Feeding; Lactation; Milk, Human; Hypoglycemic Agents; Islet Amyloid Polypeptide
• Avoid alcohol. Ingesting alcohol may increase the risk of hypoglycemia.
• Substances which lower blood glucose levels.
• Mechanisms of Action [MoA] - Amylin Agonists

Synonyms

Triproamylin; pramlintida; TRIPRO-AMYLIN; AC0137; AC137; AC-137; AC-0137; D3FM8FA78T; pramlintidum; RefChem:58316; A10BX05; DTXSID801027623; AC 137; 151126-32-8; Pramlintide; UNII-D3FM8FA78T

Frequently Asked Questions

What are the CAS number and molecular formula of Pramlintide?

CAS 151126-32-8; molecular formula C171H267N51O53S2; molecular weight — g/mol.

What other names is Pramlintide known by?

Triproamylin, pramlintida, TRIPRO-AMYLIN, AC0137, AC137, AC-137.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.