聚羟基硬脂酸

聚羟基硬脂酸（CAS 27924-99-8）：分子式 C18H36O3、分子量 300.5。

产品概览

应用领域

登记用途：Uses: CIR ingredient: Hydroxystearic Acid、Used in lithium greases、as a chemical intermediate、as a defoamer in foods、as an ingredient in cosmetics、[HSDB]、Hydroxystearic acid is used as a surfactant-cleansing agent in cosmetic products.、12-Hydroxystearic acid has been used as a textile lubricant and as a saponifiable base for greases. 12-Hydroxystearic acid-polyethylene glycol block polymers have been approved by FDA for use as surfactants、for dispersions of polyacrylamide retention and draining aids、employed prior to the sheet forming operation in the manufacture of paper and paperboard that come in contact with aqueous and fatty foods.、Lithium greases、Used for skin and hair-cleaning purposes and as emulsifiers in cosmetics.、For more Uses (Complete) data for 12-Hydroxyoctadecanoic acid (9 total)、please visit the HSDB record page.、Use Classification: EPA Safer Chemical Functional Use Classes -> Surfactants、Safer Chemical Classes -> Green circle - The chemical has been verified to be of low concern、Cosmetics -> Emulsifying、Surfactant、Cleansing、Industry Uses: Surfactant (surface active agent)、Other、Lubricating agent、Intermediate、Emulsifier、Thickening agent、Not Known or Reasonably Ascertainable、Consumer Uses: Lubricating agent、Heat stabilizer、Viscosity modifiers、Household Products: Information on 4 consumer products that contain Hydroxystearic acid in the following categories is provided:、• Personal Care、Methods of Manufacturing: 12-Hydroxystearic acid may be synthesized as follows: 2-hexylcyclododecanone is oxidized with a mixture of peracetic and permaleic acids in methylene chloride to form the lactone of Hydroxystearic acid. Alkaline hydrolysis of the lactone leads to the production of Hydroxystearic acid. Acylcyclododecanones、such as 2-hexylcyclododecanone、can be obtained by the addition of cyclododecanone at the double bond of the respective 1-alkene. This reaction occurs through a radical-chain mechanism、organic peroxides are used as initiators. The catalytic hydrogenation of castor oil to 12-Hydroxystearic acid has also been reported.、It is produced by hydrogenation of ricinoleic acid.、Fractional distillation of hydrolyzed hydrogenated castor oil.、U.S. Production: 2023: 8、500、000 - <10、000、000 lb、2022: 4、000 - <5、2021: 8、2020: 10、000 - <50、(1979) No Data、(1982) AT LEAST 2.27X10+6 G (SODIUM SALT)、Octadecanoic acid、12-hydroxy- is listed as a High Production Volume (HPV) chemical (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and、or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B、51FR21438).、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#5376]、Production volume for non-confidential chemicals reported under the 2006 Inventory Update Rule. Chemical: Octadecanoic acid、12-hydroxy-. Aggregated National Production Volume: < 500、000 lbs.、U.S. Imports: (1979) No Data、(1981) No Data、U.S. Exports: (1979) No Data、General Manufacturing Information: Petroleum Lubricating Oil and Grease Manufacturing、Paint and Coating Manufacturing、All Other Chemical Product and Preparation Manufacturing、12-hydroxy-: ACTIVE、Cosmetic oil bases are prepared with 12-hydroxystearic acid oligoesters which are produced by esterification of 12-hydroxystearic acid.、The synthesis of four sugar-based surfactants derived from glucose and (R)-12-hydroxystearic acid is described. The surfactants have a hydroxy group in the hydrophobic part、which is either free or acylated using acetyl chloride、hexanoyl chloride、or myristoyl chloride. Three of the synthesized surfactants are water-soluble and are evaluated with respect to their critical micelle concentrations and hemolytic activities. The fourth surfactant has limited water solubility and is not further included in the study. The investigated surfactants are all hemolytic close to their respective critical micelle concentration indicating that their use in parenteral formulations may be limited. Nevertheless、surfactants having the proposed structure appear as promising alternatives to existing solubilizing agents for pharmaceutical applications.。

技术档案

这个产品是什么

聚羟基硬脂酸 是一种化工化合物，登记 CAS 号为 27924-99-8，分子式 C18H36O3（分子量 300.5）。

识别信息

登记 CAS 号：27924-99-8

其分子式 C18H36O3 由 18 个碳、36 个氢、3 个氧 组成。

别名/同义词：聚羟基硬脂酸 · Polyhydroxystearic Acid · Octadecanoic acid,12-hydroxy-, homopolymer

常见问题

PubChem 公开数据