POLY-L-ASPARTIC ACID SODIUM SALT (CAS 34345-47-6) — formula C4H7NO4, molecular weight 133.10.
POLY-L-ASPARTIC ACID SODIUM SALT (CAS 34345-47-6) is classified under Food Additives, with molecular formula C4H7NO4 and molecular weight 133.10, and serves as a key raw material in the food and beverage industry — commonly applied as a food additive, nutritional supplement, or processing aid where regulatory-grade purity is required. Jinan Shenghe Chemical Co., Ltd. supplies POLY-L-ASPARTIC ACID SODIUM SALT at commercial scale with stable lot-to-lot quality, accompanied by COA and full specification documentation. Typical categorization: Food Additives.
| CAS Number | 34345-47-6 |
|---|---|
| Molecular Formula | C4H7NO4 |
| Molecular Weight | 133.10 |
| Melting Point | 270 |
| LogP | -3.89 |
| Applications | Uses: CIR ingredient: Aspartic Acid, A non-essential amino acid, [Merck Index] [REPROTOX] Used in biological and clinical studies, to make culture media, and in aspartame products (detergents, fungicides, germicides, and metal complexations), [HSDB] Used in chemical synthesis, cosmetics, and pharmaceuticals, [IUCLID] Used as a flavoring agent and nutritional supplement, [FDA], BIOLOGICAL & CLINICAL STUDIES, PREPN OF CULTURE MEDIA, ORG INTERMEDIATE, INGREDIENT OF ASPARTAME, DETERGENTS, FUNGICIDES, GERMICIDES, METAL COMPLEXATION, ASPARTIC ACID, Used in flavor reaction products and pharmaceuticals formulations and intermediates, Roborant, Used as a raw material in the synthesis of peptide drugs, For more Uses (Complete) data for (L)-ASPARTIC ACID (7 total), please visit the HSDB record page., Use (kg, approx.) in Germany (2009): >1000, Consumption (g per capita, approx.) in Germany (2009): 0.0122, Calculated removal (%): 92.1, Use Classification: Flavoring Agents -> JECFA Flavorings Index, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Cosmetics -> Antistatic, Industry Uses: Not Known or Reasonably Ascertainable, Intermediate, Chelating agent, Household Products: Information on 14 consumer products that contain Aspartic acid, disodium salt in the following categories is provided:, • Auto Products, • Commercial, Institutional, Information on 11 consumer products that contain Aspartic acid in the following categories is provided:, • Inside the Home, • Personal Care, Methods of Manufacturing: Hydrolysis of asparagine, reaction of ammonia with diethyl fumarate, L-Aspartic acid is industrially manufactured by an enzymatic process in which aspartase (l-aspartate ammonia lyase, EC 4.3.1.1) catalyzes the addition of ammonia to fumaric acid. Advantages of the enzymatic production method are higher product concentration and productivity and the formation of fewer byproducts. Thus, l-aspartic acid can be easily separated from the reaction mixture by crystallization., In 1973, an immobilized cell system based on Escherichia coli cells entrapped in polyacrylamide gel lattice was introduced for large-scale production., Formulations, Preparations: (VET) COMMERCIALLY AVAILABLE AS MIXT OF POTASSIUM & MAGNESIUM ASPARTATES= SPARTASE., AVAILABLE COMMERCIALLY AS D(-)-, L(+)-, & DL-ASPARTIC ACID., 150 G ASPARTIC ACID WAS POLYMERIZED IN PRESENCE OF H3PO4 TO GIVE 150 G POLY(DEHYDROASPARTIC ACID) WHICH WAS TREATED WITH MORPHOLINE. POLYMER WAS INCORPORATED INTO AN ANIONIC SHAMPOO WITH 4% CONCN., USP and FCC grades, 99% min grade, U.S. Production: 2023: 50, 000 - <75, 000 lb, 2022: 250, 000 - <550, 2021: 400, 2020: 250, 000 - <400, This chemical is listed as a High Production Volume (HPV) (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., (1992) No data, World market for L-aspartic acid in 1982: 450 tonnes, in 1984: 250 tonnes, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#3169], General Manufacturing Information: Synthetic Dye and Pigment Manufacturing, Not Known or Reasonably Ascertainable, Oil and Gas Drilling, Extraction, and Support activities, All Other Basic Inorganic Chemical Manufacturing, L-Aspartic acid: ACTIVE, Aspartic acid: ACTIVE, COMMONLY OCCURS IN THE L-FORM. ONE OF THE NONESSENTIAL AMINO ACIDS., ASPARTIC ACID IS A POTENTIAL FLAVOR PRECURSOR ISOLATED FROM MEAT EXTRACTS, FROM TABLE, ...ASPARTATE...FOUND IN VERY HIGH CONCN IN BRAIN..., HAS, POWERFUL EXCITATORY EFFECTS ON NEURONS IN VIRTUALLY EVERY REGION OF THE CNS. ...EFFORTS TO SUPPORT...ASPARTATE AS EXCITATORY, TRANSMITTER, ...IN MAMMALIAN CNS HAVE BEEN HAMPERED BY UNAVAILABILITY OF A CONVINCINGLY SELECTIVE RECEPTOR ANTAGONIST., ASPARTATE, POSTSYNAPTIC PHARMACOLOGY OF ASPARTATE: INCR NA+ & CATION CONDUCTANCES, DEPOLARIZES., For more General Manufacturing Information (Complete) data for (L)-ASPARTIC ACID (9 total) |
Documented applications: Uses: CIR ingredient: Aspartic Acid, A non-essential amino acid, [Merck Index] [REPROTOX] Used in biological and clinical studies, to make culture media, and in aspartame products (detergents, fungicides, germicides, and metal complexations), [HSDB] Used in chemical synthesis, cosmetics, and pharmaceuticals, [IUCLID] Used as a flavoring agent and nutritional supplement, [FDA], BIOLOGICAL & CLINICAL STUDIES, PREPN OF CULTURE MEDIA, ORG INTERMEDIATE, INGREDIENT OF ASPARTAME, DETERGENTS, FUNGICIDES, GERMICIDES, METAL COMPLEXATION, ASPARTIC ACID, Used in flavor reaction products and pharmaceuticals formulations and intermediates, Roborant, Used as a raw material in the synthesis of peptide drugs, For more Uses (Complete) data for (L)-ASPARTIC ACID (7 total), please visit the HSDB record page., Use (kg, approx.) in Germany (2009): >1000, Consumption (g per capita, approx.) in Germany (2009): 0.0122, Calculated removal (%): 92.1, Use Classification: Flavoring Agents -> JECFA Flavorings Index, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Cosmetics -> Antistatic, Industry Uses: Not Known or Reasonably Ascertainable, Intermediate, Chelating agent, Household Products: Information on 14 consumer products that contain Aspartic acid, disodium salt in the following categories is provided:, • Auto Products, • Commercial, Institutional, Information on 11 consumer products that contain Aspartic acid in the following categories is provided:, • Inside the Home, • Personal Care, Methods of Manufacturing: Hydrolysis of asparagine, reaction of ammonia with diethyl fumarate, L-Aspartic acid is industrially manufactured by an enzymatic process in which aspartase (l-aspartate ammonia lyase, EC 4.3.1.1) catalyzes the addition of ammonia to fumaric acid. Advantages of the enzymatic production method are higher product concentration and productivity and the formation of fewer byproducts. Thus, l-aspartic acid can be easily separated from the reaction mixture by crystallization., In 1973, an immobilized cell system based on Escherichia coli cells entrapped in polyacrylamide gel lattice was introduced for large-scale production., Formulations, Preparations: (VET) COMMERCIALLY AVAILABLE AS MIXT OF POTASSIUM & MAGNESIUM ASPARTATES= SPARTASE., AVAILABLE COMMERCIALLY AS D(-)-, L(+)-, & DL-ASPARTIC ACID., 150 G ASPARTIC ACID WAS POLYMERIZED IN PRESENCE OF H3PO4 TO GIVE 150 G POLY(DEHYDROASPARTIC ACID) WHICH WAS TREATED WITH MORPHOLINE. POLYMER WAS INCORPORATED INTO AN ANIONIC SHAMPOO WITH 4% CONCN., USP and FCC grades, 99% min grade, U.S. Production: 2023: 50, 000 - <75, 000 lb, 2022: 250, 000 - <550, 2021: 400, 2020: 250, 000 - <400, This chemical is listed as a High Production Volume (HPV) (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., (1992) No data, World market for L-aspartic acid in 1982: 450 tonnes, in 1984: 250 tonnes, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#3169], General Manufacturing Information: Synthetic Dye and Pigment Manufacturing, Not Known or Reasonably Ascertainable, Oil and Gas Drilling, Extraction, and Support activities, All Other Basic Inorganic Chemical Manufacturing, L-Aspartic acid: ACTIVE, Aspartic acid: ACTIVE, COMMONLY OCCURS IN THE L-FORM. ONE OF THE NONESSENTIAL AMINO ACIDS., ASPARTIC ACID IS A POTENTIAL FLAVOR PRECURSOR ISOLATED FROM MEAT EXTRACTS, FROM TABLE, ...ASPARTATE...FOUND IN VERY HIGH CONCN IN BRAIN..., HAS, POWERFUL EXCITATORY EFFECTS ON NEURONS IN VIRTUALLY EVERY REGION OF THE CNS. ...EFFORTS TO SUPPORT...ASPARTATE AS EXCITATORY, TRANSMITTER, ...IN MAMMALIAN CNS HAVE BEEN HAMPERED BY UNAVAILABILITY OF A CONVINCINGLY SELECTIVE RECEPTOR ANTAGONIST., ASPARTATE, POSTSYNAPTIC PHARMACOLOGY OF ASPARTATE: INCR NA+ & CATION CONDUCTANCES, DEPOLARIZES., For more General Manufacturing Information (Complete) data for (L)-ASPARTIC ACID (9 total).
POLY-L-ASPARTIC ACID SODIUM SALT is a chemical compound with CAS registry number 34345-47-6 and molecular formula C4H7NO4 (molecular weight 133.10).
CAS number: 34345-47-6
Its molecular formula C4H7NO4 comprises 4 C, 7 H, 1 N, 4 O atoms.
Also known as: POLY-L-ASPARTIC ACID SODIUM SALT · 聚天门冬氨酸；聚天冬氨酸钠;PASP
The CAS registry number of POLY-L-ASPARTIC ACID SODIUM SALT is 34345-47-6.
Molecular formula C4H7NO4, molecular weight 133.10.
It is also registered under: POLY-L-ASPARTIC ACID SODIUM SALT, 聚天门冬氨酸；聚天冬氨酸钠;PASP.
Recorded applications: Uses: CIR ingredient: Aspartic Acid, A non-essential amino acid, [Merck Index] [REPROTOX] Used in biological and clinical studies, to make culture media, and in aspartame products (detergents, fungicides, germicides, and metal complexations), [HSDB] Used in chemical synthesis, cosmetics, and pharmaceuticals, [IUCLID] Used as a flavoring agent and nutritional supplement, [FDA], BIOLOGICAL & CLINICAL STUDIES, PREPN OF CULTURE MEDIA, ORG INTERMEDIATE, INGREDIENT OF ASPARTAME, DETERGENTS, FUNGICIDES, GERMICIDES, METAL COMPLEXATION, ASPARTIC ACID, Used in flavor reaction products and pharmaceuticals formulations and intermediates, Roborant, Used as a raw material in the synthesis of peptide drugs, For more Uses (Complete) data for (L)-ASPARTIC ACID (7 total), please visit the HSDB record page., Use (kg, approx.) in Germany (2009): >1000, Consumption (g per capita, approx.) in Germany (2009): 0.0122, Calculated removal (%): 92.1, Use Classification: Flavoring Agents -> JECFA Flavorings Index, Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes, Cosmetics -> Antistatic, Industry Uses: Not Known or Reasonably Ascertainable, Intermediate, Chelating agent, Household Products: Information on 14 consumer products that contain Aspartic acid, disodium salt in the following categories is provided:, • Auto Products, • Commercial, Institutional, Information on 11 consumer products that contain Aspartic acid in the following categories is provided:, • Inside the Home, • Personal Care, Methods of Manufacturing: Hydrolysis of asparagine, reaction of ammonia with diethyl fumarate, L-Aspartic acid is industrially manufactured by an enzymatic process in which aspartase (l-aspartate ammonia lyase, EC 4.3.1.1) catalyzes the addition of ammonia to fumaric acid. Advantages of the enzymatic production method are higher product concentration and productivity and the formation of fewer byproducts. Thus, l-aspartic acid can be easily separated from the reaction mixture by crystallization., In 1973, an immobilized cell system based on Escherichia coli cells entrapped in polyacrylamide gel lattice was introduced for large-scale production., Formulations, Preparations: (VET) COMMERCIALLY AVAILABLE AS MIXT OF POTASSIUM & MAGNESIUM ASPARTATES= SPARTASE., AVAILABLE COMMERCIALLY AS D(-)-, L(+)-, & DL-ASPARTIC ACID., 150 G ASPARTIC ACID WAS POLYMERIZED IN PRESENCE OF H3PO4 TO GIVE 150 G POLY(DEHYDROASPARTIC ACID) WHICH WAS TREATED WITH MORPHOLINE. POLYMER WAS INCORPORATED INTO AN ANIONIC SHAMPOO WITH 4% CONCN., USP and FCC grades, 99% min grade, U.S. Production: 2023: 50, 000 - <75, 000 lb, 2022: 250, 000 - <550, 2021: 400, 2020: 250, 000 - <400, This chemical is listed as a High Production Volume (HPV) (65FR81686). Chemicals listed as HPV were produced in or imported into the U.S. in >1 million pounds in 1990 and, or 1994. The HPV list is based on the 1990 Inventory Update Rule. (IUR) (40 CFR part 710 subpart B, 51FR21438)., (1992) No data, World market for L-aspartic acid in 1982: 450 tonnes, in 1984: 250 tonnes, Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#3169], General Manufacturing Information: Synthetic Dye and Pigment Manufacturing, Not Known or Reasonably Ascertainable, Oil and Gas Drilling, Extraction, and Support activities, All Other Basic Inorganic Chemical Manufacturing, L-Aspartic acid: ACTIVE, Aspartic acid: ACTIVE, COMMONLY OCCURS IN THE L-FORM. ONE OF THE NONESSENTIAL AMINO ACIDS., ASPARTIC ACID IS A POTENTIAL FLAVOR PRECURSOR ISOLATED FROM MEAT EXTRACTS, FROM TABLE, ...ASPARTATE...FOUND IN VERY HIGH CONCN IN BRAIN..., HAS, POWERFUL EXCITATORY EFFECTS ON NEURONS IN VIRTUALLY EVERY REGION OF THE CNS. ...EFFORTS TO SUPPORT...ASPARTATE AS EXCITATORY, TRANSMITTER, ...IN MAMMALIAN CNS HAVE BEEN HAMPERED BY UNAVAILABILITY OF A CONVINCINGLY SELECTIVE RECEPTOR ANTAGONIST., ASPARTATE, POSTSYNAPTIC PHARMACOLOGY OF ASPARTATE: INCR NA+ & CATION CONDUCTANCES, DEPOLARIZES., For more General Manufacturing Information (Complete) data for (L)-ASPARTIC ACID (9 total).
Independent reference data for POLY-L-ASPARTIC ACID SODIUM SALT (CAS 34345-47-6), compiled from public chemistry databases.
| CAS 号 | 34345-47-6 |
|---|---|
| PubChem CID | 5960 |
| 分子式 | C4H7NO4 |
| IUPAC 名称 | (2S)-2-aminobutanedioic acid |
| UNII（FDA） | 30KYC7MIAI |
| FEMA 编号 | 3656 |
| JECFA 编号 | 1429 |
| Molecular Weight | 133.10 |
|---|---|
| XLogP3 | -2.8 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 3 |
| Exact Mass | 133.03750770 |
| Monoisotopic Mass | 133.03750770 |
| Topological Polar Surface Area | 101 |
| Heavy Atom Count | 9 |
| Melting Point | 270 |
|---|---|
| Melting Point | 270-271 °C |
| Melting Point | 270 °C |
| Solubility | 5390 |
| Solubility | In water, 5,360 mg/L at 25 °C |
| Solubility | 5.39 mg/mL |
| Density | 1.6603 at 13 °C |
| Density | 1.7 g/cm³ |
| Vapor Pressure | 0.0000013 [mmHg] |
| LogP | -3.89 |
L-aspartic acid; aspartic acid; 56-84-8; (2S)-2-aminobutanedioic acid; Asparagic acid; L-Aminosuccinic acid; (S)-2-Aminosuccinic acid; Asparaginic acid; L-Asparaginic acid; L-Asparagic acid; (S)-Aspartic acid; Aspartic acid, L-; (S)-Aminobutanedioic acid; L-Asparaginsaeure; Acidum asparticum; L-(+)-Aspartic acid
| 法规与食品接触 | EU Flavoring substances FDA Substance added to food: FLAVOR ENHANCER, FLAVORING AGENT OR ADJUVANT, NUTRIENT SUPPLEMENT Flavoring Agents FLAVOURING_AGENT: Flavouring Agent No safety concern at current levels of intake when used as a flavouring agent TRS 928-JECFA 63/98 |
|---|---|
| GHS 通报统计 | 94.4% (340 / 360) |
| GHS 通报统计 | 94.4% (340 / 360) |
|---|
聚天门冬氨酸；聚天冬氨酸钠;PASP · CAS 34345-47-6 · C4H7NO4. UNII 30KYC7MIAI. Melting Point: 270; Melting Point: 270-271 °C; Melting Point: 270 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 聚天门冬氨酸；聚天冬氨酸钠;PASP