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匹马范色林

CAS 706779-91-1C25H34FN3O2MW 427.6

匹马范色林(CAS 706779-91-1):分子式 C25H34FN3O2、分子量 427.6。

产品概览

CAS号706779-91-1
分子式C25H34FN3O2
分子量427.6
熔点117-119
沸点604.2±55.0
LogP4.5

技术档案

这个产品是什么

匹马范色林 是一种化工化合物,登记 CAS 号为 706779-91-1,分子式 C25H34FN3O2(分子量 427.6)。

识别信息

登记 CAS 号:706779-91-1

其分子式 C25H34FN3O2 由 25 个碳、34 个氢、1 个氟、3 个氮、2 个氧 组成。

别名/同义词:匹马范色林 · Pimavanserin

常见问题

匹马范色林 的 CAS 号是多少?

匹马范色林 的 CAS 登记号为 706779-91-1。

匹马范色林 的分子式与分子量是多少?

分子式 C25H34FN3O2,分子量 427.6。

匹马范色林 还有哪些别名?

别名/同义词:匹马范色林、Pimavanserin。

PubChem 公开数据

匹马范色林(CAS 706779-91-1)的独立参考数据,整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number706779-91-1
PubChem CID10071196
Molecular formulaC25H34FN3O2
IUPAC name1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea
UNII (FDA)JZ963P0DIK

计算分子描述符

Molecular Weight427.6
XLogP34.5
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count8
Exact Mass427.26350550
Monoisotopic Mass427.26350550
Topological Polar Surface Area44.8
Heavy Atom Count31

在册的理化数值

Boiling Point604.2±55.0
Melting Point117-119
Dissociation Constants13.52±0.46

在册的记载用途

    Pimavanserin is indicated for the treatment of hallucinations and delusions associated with Parkinson’s disease psychosis.Pimavanserin is an atypical antipsychotic that received FDA approval in the U.S. in 2016 for hallucinations and delusions that accompany Parkinson disease psychosis (PDP). It is the first and only FDA-approved medication for PDP. It had initially received Breakthrough Therapy status from the FDA in 2014. In the phase III clinical trial that paved the way for FDA approval, patients receiving pimavanserin demonstrated significant improvement in the frequency and/or severity of hallucinations and/or delusions without

    同义词与商品名

    Pimavanserin; 706779-91-1; ACP-103; pimavanserina; pimavanserine; JZ963P0DIK; CHEBI:133017; DTXSID90990906; 1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-[[4-(2-methylpropoxy)phenyl]methyl]urea; N-(4-Fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide; ACP 103; N-(4-Fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl)carbamide; 1-[(4-fluorophenyl)methyl]-1-(1-methylpiperidin-4-yl)-3-{[4-(2-methylpropoxy)phenyl]methyl}urea; pimavanserinum; 1-((4-fluorophenyl)methyl)-1-(1-methylpiperidin-4-yl)-3-((4-(2-methylpropoxy)phenyl)methyl)urea; RefChem:59074

    公开数据库对它的描述

    Pimavanserin · CAS 706779-91-1 · C25H34FN3O2. UNII JZ963P0DIK. Boiling Point: 604.2±55.0; Melting Point: 117-119; Dissociation Constants: 13.52±0.46.

    数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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