苯氧基甲基青霉素酸*游离酸（CAS 87-08-1）：分子式 C16H18N2O5S、分子量 350.4。
| CAS号 | 87-08-1 |
|---|---|
| 分子式 | C16H18N2O5S |
| 分子量 | 350.4 |
| 熔点 | 120 - 128 °C |
| LogP | 2.09 |
| 应用领域 | Uses: Used to prepare 6-APA on a large scale by selective enzymatic hydrolysis、MEDICATION、MEDICATION (VET)、Use (kg、approx.) in Germany (2009): >25000、exact) in Germany (2009): 48895、Consumption (g per capita、approx.) in Germany (2009): 0.305、exact) in Germany (2009): 0.597、Excretion rate: 1、Calculated removal (%): 23.1、Methods of Manufacturing: Natural penicillins are produced by fermentation of mutant strains of Penicillium chrysogenum. ... Penicillin ... V、is、produced by adding ... phenoxyacetic acid ... to the culture media.、Obtained by adding 2-phenoxyethanol to the Penicillium culture using yeast autolyzate as source of nitrogen.、Impurities: Commercially available penicillin ... V preparations may contain small amounts of high molecular weight protein impurities that originate from the fermentation process used to produce the drugs.、Formulations、Preparations: ... Penicillin V is commercially available as the acid and its potassium salt.、Generic: Powder for oral solution (plain、buffered) and oral suspension 125 and 250 mg、5 ml、tablets 250 and 500 mg.、U.S. Production: (1985)、Data not reported、U.S. Imports: (1985) 3.44X10+7 g、Penicillins、NSPF、U.S. Exports: (1985) 1.28X10+9 g、General Manufacturing Information: Grade: NF、Although potency of penicillin V ... is generally expressed in terms of the weight of penicillin V、potency of the drugs may be expressed in terms of USP penicillin V units. For labeling purposes、each mg of penicillin V contained in penicillin V ... prepn is considered equivalent to 1695 penicillin V units.、The problem of antibiotic contamination of milk requires that the dairy operator、veterinarian、and milk processor be aware of the sensitizing ability of penicillin and the importance of adherence to drug withdrawal times. |
登记用途：Uses: Used to prepare 6-APA on a large scale by selective enzymatic hydrolysis、MEDICATION、MEDICATION (VET)、Use (kg、approx.) in Germany (2009): >25000、exact) in Germany (2009): 48895、Consumption (g per capita、approx.) in Germany (2009): 0.305、exact) in Germany (2009): 0.597、Excretion rate: 1、Calculated removal (%): 23.1、Methods of Manufacturing: Natural penicillins are produced by fermentation of mutant strains of Penicillium chrysogenum. ... Penicillin ... V、is、produced by adding ... phenoxyacetic acid ... to the culture media.、Obtained by adding 2-phenoxyethanol to the Penicillium culture using yeast autolyzate as source of nitrogen.、Impurities: Commercially available penicillin ... V preparations may contain small amounts of high molecular weight protein impurities that originate from the fermentation process used to produce the drugs.、Formulations、Preparations: ... Penicillin V is commercially available as the acid and its potassium salt.、Generic: Powder for oral solution (plain、buffered) and oral suspension 125 and 250 mg、5 ml、tablets 250 and 500 mg.、U.S. Production: (1985)、Data not reported、U.S. Imports: (1985) 3.44X10+7 g、Penicillins、NSPF、U.S. Exports: (1985) 1.28X10+9 g、General Manufacturing Information: Grade: NF、Although potency of penicillin V ... is generally expressed in terms of the weight of penicillin V、potency of the drugs may be expressed in terms of USP penicillin V units. For labeling purposes、each mg of penicillin V contained in penicillin V ... prepn is considered equivalent to 1695 penicillin V units.、The problem of antibiotic contamination of milk requires that the dairy operator、veterinarian、and milk processor be aware of the sensitizing ability of penicillin and the importance of adherence to drug withdrawal times.。
苯氧基甲基青霉素酸*游离酸 是一种化工化合物，登记 CAS 号为 87-08-1，分子式 C16H18N2O5S（分子量 350.4）。
登记 CAS 号：87-08-1
其分子式 C16H18N2O5S 由 16 个碳、18 个氢、2 个氮、5 个氧、1 个硫 组成。
别名/同义词：苯氧基甲基青霉素酸*游离酸 · phenoxymethyl penicillinic acid*free acid
苯氧基甲基青霉素酸*游离酸 的 CAS 登记号为 87-08-1。
分子式 C16H18N2O5S，分子量 350.4。
别名/同义词：苯氧基甲基青霉素酸*游离酸、phenoxymethyl penicillinic acid*free acid。
登记用途：Uses: Used to prepare 6-APA on a large scale by selective enzymatic hydrolysis、MEDICATION、MEDICATION (VET)、Use (kg、approx.) in Germany (2009): >25000、exact) in Germany (2009): 48895、Consumption (g per capita、approx.) in Germany (2009): 0.305、exact) in Germany (2009): 0.597、Excretion rate: 1、Calculated removal (%): 23.1、Methods of Manufacturing: Natural penicillins are produced by fermentation of mutant strains of Penicillium chrysogenum. ... Penicillin ... V、is、produced by adding ... phenoxyacetic acid ... to the culture media.、Obtained by adding 2-phenoxyethanol to the Penicillium culture using yeast autolyzate as source of nitrogen.、Impurities: Commercially available penicillin ... V preparations may contain small amounts of high molecular weight protein impurities that originate from the fermentation process used to produce the drugs.、Formulations、Preparations: ... Penicillin V is commercially available as the acid and its potassium salt.、Generic: Powder for oral solution (plain、buffered) and oral suspension 125 and 250 mg、5 ml、tablets 250 and 500 mg.、U.S. Production: (1985)、Data not reported、U.S. Imports: (1985) 3.44X10+7 g、Penicillins、NSPF、U.S. Exports: (1985) 1.28X10+9 g、General Manufacturing Information: Grade: NF、Although potency of penicillin V ... is generally expressed in terms of the weight of penicillin V、potency of the drugs may be expressed in terms of USP penicillin V units. For labeling purposes、each mg of penicillin V contained in penicillin V ... prepn is considered equivalent to 1695 penicillin V units.、The problem of antibiotic contamination of milk requires that the dairy operator、veterinarian、and milk processor be aware of the sensitizing ability of penicillin and the importance of adherence to drug withdrawal times.。
苯氧基甲基青霉素酸*游离酸（CAS 87-08-1）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 87-08-1 |
|---|---|
| PubChem CID | 6869 |
| Molecular formula | C16H18N2O5S |
| IUPAC name | (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid |
| UNII (FDA) | Z61I075U2W |
| Molecular Weight | 350.4 |
|---|---|
| XLogP3 | 2.1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 6 |
| Rotatable Bond Count | 5 |
| Exact Mass | 350.09364285 |
| Monoisotopic Mass | 350.09364285 |
| Topological Polar Surface Area | 121 |
| Heavy Atom Count | 24 |
| Melting Point | 120 - 128 °C |
|---|---|
| Solubility | <0.1 g/100mL |
| Solubility | 4.54e-01 g/L |
| LogP | 2.09 |
| LogP | 1.4 |
| LogP | 1.95 |
| Dissociation Constants | 2.735 |
| Dissociation Constants | 2.79 |
| Dissociation Constants | pKa 2.73 |
| Other Experimental Properties | 120-128 °C (decomp) |
penicillin v; Phenoxymethylpenicillin; 87-08-1; Oracillin; Vebecillin; Penicillin phenoxymethyl; Phenopenicillin; Distaquaine V; Meropenin; Phenomycilline; V-Cillin; Fenospen; Beromycin; Fenacilin; Stabicillin; Apopen
| Reported hazard statements | H317 (100%), H334 (100%) |
|---|
H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]
H334 (100%): May cause allergy or asthma symptoms or breathing difficulties if inhaled [Danger Sensitization, respiratory]
phenoxymethyl penicillinic acid*free acid · CAS 87-08-1 · C16H18N2O5S. UNII Z61I075U2W. Melting Point: 120 - 128 °C; Solubility: <0.1 g/100mL; Solubility: 4.54e-01 g/L.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: phenoxymethyl penicillinic acid*free acid