Penicillin G Sodium

Description

Penicillin G Sodium · CAS 69-57-8 · C16H17N2NaO4S. UNII YS5LY7JF4N. Solubility: 50 to 100 mg/mL at 77 °F (NTP, 1992).

Identification

CAS Registry Number	69-57-8
PubChem CID	23668834
Molecular formula	C16H17N2NaO4S
IUPAC name	sodium (2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenylacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate
UNII (FDA)	YS5LY7JF4N

Computed Descriptors

Molecular Weight	356.4
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Exact Mass	356.08067248
Monoisotopic Mass	356.08067248
Topological Polar Surface Area	115
Heavy Atom Count	24
Formal Charge	0
Complexity	536

Physical & Chemical Properties

Solubility	50 to 100 mg/mL at 77 °F (NTP, 1992)

Physical description & handling notes

• Penicillin g, sodium salt is a white to slightly yellow crystalline powder with a faint odor. pH (10% solution) 5.5-7.5. (NTP, 1992)
• 408 to 414 °F (decomposes) (NTP, 1992)
• 1.41 (NTP, 1992) - Denser than water; will sink

Regulatory Status

GHS notification summary	1.2% (1 / 82)

GHS Hazard Classification

GHS notification summary	1.2% (1 / 82)
Reported hazard statements	H225 (12.2%), H301 (12.2%), H314 (12.2%), H317 (84.1%), H334 (64.6%)

Documented Uses

• Penicillin G (potassium or sodium) is an antibacterial prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of certain serious bacterialinfections, such as pneumonia, meningitis, gonorrhea, syphilis, and others.
• Pneumonia and syphilis can be opportunistic infections (OI) of HIV.
• Substances that inhibit the growth or reproduction of BACTERIA.
• Penicillins [CS]; Penicillin-class Antibacterial [EPC]

Synonyms

Penicillin G sodium; Penicillin G sodium salt; 69-57-8; Crystapen; Benzylpenicillin sodium; BENZYLPENICILLIN SODIUM SALT; American penicillin; Sodium penicillin G; Sodium penicillin; Mycofarm; Penilaryn; Veticillin; Sodium benzylpenicillinate; Sodium penicillin II; Sodium benzylpenicillin; Pen-A-Brasive

Frequently Asked Questions

What are the CAS number and molecular formula of Penicillin G Sodium?

CAS 69-57-8; molecular formula C16H17N2NaO4S; molecular weight — g/mol.

What other names is Penicillin G Sodium known by?

Penicillin G sodium, Penicillin G sodium salt, 69-57-8, Crystapen, Benzylpenicillin sodium, BENZYLPENICILLIN SODIUM SALT.

Is Penicillin G Sodium classified as hazardous?

1.2% of GHS notifications report no hazard classification (1 of 82).

What are the key physical properties of Penicillin G Sodium?

Solubility: 50 to 100 mg/mL at 77 °F (NTP, 1992).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.