帕唑帕尼（CAS 444731-52-6）：分子式 C21H23N7O2S、分子量 437.5。
| CAS号 | 444731-52-6 |
|---|---|
| 分子式 | C21H23N7O2S |
| 分子量 | 437.5 |
| LogP | 3.3 |
| 应用领域 | Uses: MEDICATION、THERAPEUTIC CATEGORY: Antineoplastic、Methods of Manufacturing: Preparation: A. Boloor et al.、World Intellectual Property Organization patent 02059110 (2002 to Glaxo)、eidem、United States of America patent 7105530 (2006 to SKB).、The manufacturing process is a standard wet granulation process and consists of the following steps: granulation、milling、drying、blending and compression. The tablets are then film-coated.、Formulations、Preparations: Oral: Tablets、film-coated: 200 mg (of pazopanib)、Votrient (GlaxoSmithKline).、Pazopanib hydrochloride |
登记用途：Uses: MEDICATION、THERAPEUTIC CATEGORY: Antineoplastic、Methods of Manufacturing: Preparation: A. Boloor et al.、World Intellectual Property Organization patent 02059110 (2002 to Glaxo)、eidem、United States of America patent 7105530 (2006 to SKB).、The manufacturing process is a standard wet granulation process and consists of the following steps: granulation、milling、drying、blending and compression. The tablets are then film-coated.、Formulations、Preparations: Oral: Tablets、film-coated: 200 mg (of pazopanib)、Votrient (GlaxoSmithKline).、Pazopanib hydrochloride。
帕唑帕尼 是一种化工化合物，登记 CAS 号为 444731-52-6，分子式 C21H23N7O2S（分子量 437.5）。
登记 CAS 号：444731-52-6
其分子式 C21H23N7O2S 由 21 个碳、23 个氢、7 个氮、2 个氧、1 个硫 组成。
别名/同义词：帕唑帕尼 · Pazopanib
帕唑帕尼 的 CAS 登记号为 444731-52-6。
分子式 C21H23N7O2S，分子量 437.5。
别名/同义词：帕唑帕尼、Pazopanib。
登记用途：Uses: MEDICATION、THERAPEUTIC CATEGORY: Antineoplastic、Methods of Manufacturing: Preparation: A. Boloor et al.、World Intellectual Property Organization patent 02059110 (2002 to Glaxo)、eidem、United States of America patent 7105530 (2006 to SKB).、The manufacturing process is a standard wet granulation process and consists of the following steps: granulation、milling、drying、blending and compression. The tablets are then film-coated.、Formulations、Preparations: Oral: Tablets、film-coated: 200 mg (of pazopanib)、Votrient (GlaxoSmithKline).、Pazopanib hydrochloride。
帕唑帕尼（CAS 444731-52-6）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 444731-52-6 |
|---|---|
| PubChem CID | 10113978 |
| Molecular formula | C21H23N7O2S |
| IUPAC name | 5-[[4-[(2,3-dimethylindazol-6-yl)-methylamino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide |
| UNII (FDA) | 7RN5DR86CK |
| Molecular Weight | 437.5 |
|---|---|
| XLogP3 | 3.1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 5 |
| Exact Mass | 437.16339418 |
| Monoisotopic Mass | 437.16339418 |
| Topological Polar Surface Area | 127 |
| Heavy Atom Count | 31 |
| LogP | 3.3 |
|---|
Pazopanib; 444731-52-6; GW786034; 5-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide; pazopanibum; DTXSID8048733; 7RN5DR86CK; NSC-752782; GW780604; GW-780604; 5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide; DTXCID1028659; CHEBI:71219; Benzenesulfonamide, 5-((4-((2,3-dimethyl-2H-indazol-6-yl)methylamino)-2-pyrimidinyl)amino)-2-methyl-; 5-({4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl}amino)-2-methylbenzenesulfonamide; Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-
| Reported hazard statements | H302 (50%), H315 (50%), H319 (50%), H335 (50%), H361 (25%), H373 (25%), H411 (25%) |
|---|
H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (50%): Causes skin irritation [Warning Skin corrosion/irritation]
Pazopanib · CAS 444731-52-6 · C21H23N7O2S. UNII 7RN5DR86CK. LogP: 3.3.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Pazopanib