罂粟碱（碱和/或未指定的盐）（CAS 58-74-2）：分子式 C20H21NO4、分子量 339.4。
| CAS号 | 58-74-2 |
|---|---|
| 分子式 | C20H21NO4 |
| 分子量 | 339.4 |
| 熔点 | 226 |
| 沸点 | Sublimes at 135 °C |
| LogP | log Kow = 2.95 |
| 应用领域 | Uses: A vasodilator used for treatment of hypertension (also as the hydrochloride which is soluble in water).、MEDICATION (VET)、MEDICATION、Use Classification: Pharmaceuticals -> Animal Drugs -> Approved in Taiwan、Methods of Manufacturing: From opium or by synthesis.、Papaverine was synthesized via the Bischler-Napieralski reaction as follows: the Schotten-Baumann reaction between the phenethylamine and the acyl chloride gave the amide. Cyclization with phosphorous pentoxide afforded the 3、4-dihydroisoquinoline. Mild dehydrogenation of、3、4-dihydroisoquinoline、gave papaverine.、Formulations、Preparations: Artegodan、Cepaverin、Cerebid、Cerespan、Dynovas、Optenyl、Pameion、Panergon、Papital T.R.、Pavabid、Pavacen、Pavadel、Pavagen、Pavakey、Pavased、Spasmo-Nit、Therapav、Vasal、Vasospan、Papverine hydrochloride、Table: Papaverine Hydrochloride Preparations [Table#4478] |
登记用途：Uses: A vasodilator used for treatment of hypertension (also as the hydrochloride which is soluble in water).、MEDICATION (VET)、MEDICATION、Use Classification: Pharmaceuticals -> Animal Drugs -> Approved in Taiwan、Methods of Manufacturing: From opium or by synthesis.、Papaverine was synthesized via the Bischler-Napieralski reaction as follows: the Schotten-Baumann reaction between the phenethylamine and the acyl chloride gave the amide. Cyclization with phosphorous pentoxide afforded the 3、4-dihydroisoquinoline. Mild dehydrogenation of、3、4-dihydroisoquinoline、gave papaverine.、Formulations、Preparations: Artegodan、Cepaverin、Cerebid、Cerespan、Dynovas、Optenyl、Pameion、Panergon、Papital T.R.、Pavabid、Pavacen、Pavadel、Pavagen、Pavakey、Pavased、Spasmo-Nit、Therapav、Vasal、Vasospan、Papverine hydrochloride、Table: Papaverine Hydrochloride Preparations [Table#4478]。
罂粟碱（碱和/或未指定的盐） 是一种化工化合物，登记 CAS 号为 58-74-2，分子式 C20H21NO4（分子量 339.4）。
登记 CAS 号：58-74-2
其分子式 C20H21NO4 由 20 个碳、21 个氢、1 个氮、4 个氧 组成。
别名/同义词：罂粟碱（碱和/或未指定的盐） · Papaverine (base and/or unspecified salts)
罂粟碱（碱和/或未指定的盐） 的 CAS 登记号为 58-74-2。
分子式 C20H21NO4，分子量 339.4。
别名/同义词：罂粟碱（碱和/或未指定的盐）、Papaverine (base and/or unspecified salts)。
登记用途：Uses: A vasodilator used for treatment of hypertension (also as the hydrochloride which is soluble in water).、MEDICATION (VET)、MEDICATION、Use Classification: Pharmaceuticals -> Animal Drugs -> Approved in Taiwan、Methods of Manufacturing: From opium or by synthesis.、Papaverine was synthesized via the Bischler-Napieralski reaction as follows: the Schotten-Baumann reaction between the phenethylamine and the acyl chloride gave the amide. Cyclization with phosphorous pentoxide afforded the 3、4-dihydroisoquinoline. Mild dehydrogenation of、3、4-dihydroisoquinoline、gave papaverine.、Formulations、Preparations: Artegodan、Cepaverin、Cerebid、Cerespan、Dynovas、Optenyl、Pameion、Panergon、Papital T.R.、Pavabid、Pavacen、Pavadel、Pavagen、Pavakey、Pavased、Spasmo-Nit、Therapav、Vasal、Vasospan、Papverine hydrochloride、Table: Papaverine Hydrochloride Preparations [Table#4478]。
罂粟碱（碱和/或未指定的盐）（CAS 58-74-2）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 58-74-2 |
|---|---|
| PubChem CID | 4680 |
| Molecular formula | C20H21NO4 |
| IUPAC name | 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline |
| UNII (FDA) | DAA13NKG2Q |
| Molecular Weight | 339.4 |
|---|---|
| XLogP3 | 3.9 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 6 |
| Exact Mass | 339.14705815 |
| Monoisotopic Mass | 339.14705815 |
| Topological Polar Surface Area | 49.8 |
| Heavy Atom Count | 25 |
| Boiling Point | Sublimes at 135 °C |
|---|---|
| Melting Point | 226 |
| Melting Point | 147.5 °C |
| Solubility | In water, 3.733X10-5 mg/L at 37.5 °C |
| Solubility | In water, 35 mg/L at 17 °C |
| Solubility | 1.29e-02 g/L |
| Density | 1.337 g/cu cm at 20 °C |
| LogP | log Kow = 2.95 |
| LogP | 2.95 |
| Dissociation Constants | pKa = 8.07 at 25 °C |
papaverine; 58-74-2; Robaxapap; 1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline; 6,7-Dimethoxy-1-veratrylisoquinoline; 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxyisoquinoline; Pavacap; Papaverinum; DAA13NKG2Q; 1-((3,4-Dimethoxyphenyl)methyl)-6,7-dimethoxyisoquinoline; NSC-136630; Isoquinoline, 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-; Isoquinoline, 1-((3,4-dimethoxyphenyl)methyl)-6,7-dimethoxy-; DTXSID4023418; Pavatym; CHEBI:28241
| Reported hazard statements | H302 |
|---|
H302: Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
Papaverine (base and/or unspecified salts) · CAS 58-74-2 · C20H21NO4. UNII DAA13NKG2Q. Boiling Point: Sublimes at 135 °C; Melting Point: 226; Melting Point: 147.5 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Papaverine (base and/or unspecified salts)