泮托拉唑（CAS 102625-70-7）：分子式 C16H15F2N3O4S、分子量 383.4。
| CAS号 | 102625-70-7 |
|---|---|
| 分子式 | C16H15F2N3O4S |
| 分子量 | 383.4 |
| 熔点 | 149-150 |
| 沸点 | 586.9±60.0 °C at 760 mmHg |
| LogP | 2.05 |
| 应用领域 | Uses: Medication: Antiulcerative、Use (kg、approx.) in Germany (2009): >10000、exact) in Germany (2009): 20548、Use (kg) in USA (2002): 8200、Use (kg) in France (2004): 5287、Consumption (g per capita、approx.) in Germany (2009): 0.122、exact) in Germany (2009): 0.251、Consumption (g per capita) in the USA (2002): 0.0291、Consumption (g per capita) in France (2004): 0.0875、Excretion rate: 0.06、Calculated removal (%): 9.8、Formulations、Preparations: Pantoprazole is available as enteric coated tablets containing 45.1 mg of the sodium salt sesquihydrate equivalent to 40 mg ... of the free anhydrous acid、and as a lyophylisate for iv infusion.、Trade name: Protonix、General Manufacturing Information: Preparation: B. Kohl et al、EP 166287、eidem、US 4758579 (1986、1988 both to Byk Gluden)、Information available in 2004 indicated that Pantoprazole was used in the manufacture of pharmaceutical preparations in the following countries: Algeria、Argentina、Bahrain、Brazil、Costa Rica、Dominican Republic、El Salvador、Guatemala、Honduras、India、Iraq、Israel、Jordan、Lebanon、Libyan Arab Jamahiriya、Luxembourg、Malaysia、Mexico、Nicaragua、Nigeria、Oman、Panama、Poland、Portugal、Romania、Saudi Arabia、Singapore、Somalia、South Africa、Sudan、Thailand、Tunisia、United Arab Emirates、Yemen (1、2)、Information available in 2004 indicated that Pantoprazole sodium was used in the manufacture of pharmaceutical preparations in the following countries: Argentina、Australia、Austria、Belgium、Canada、Chile、Colombia、Croatia、Czech Republic、Denmark、Ecuador、Finland、France、Germany、Greece、Hong Kong、Hungary、Indonesia、Ireland、Italy、Netherlands、New Zealand、Norway、Slovenia、Spain、Sweden、Switzerland、Turkey、United Kingdom、USA、Yugoslavia (1、Pantoprazole sodium |
登记用途：Uses: Medication: Antiulcerative、Use (kg、approx.) in Germany (2009): >10000、exact) in Germany (2009): 20548、Use (kg) in USA (2002): 8200、Use (kg) in France (2004): 5287、Consumption (g per capita、approx.) in Germany (2009): 0.122、exact) in Germany (2009): 0.251、Consumption (g per capita) in the USA (2002): 0.0291、Consumption (g per capita) in France (2004): 0.0875、Excretion rate: 0.06、Calculated removal (%): 9.8、Formulations、Preparations: Pantoprazole is available as enteric coated tablets containing 45.1 mg of the sodium salt sesquihydrate equivalent to 40 mg ... of the free anhydrous acid、and as a lyophylisate for iv infusion.、Trade name: Protonix、General Manufacturing Information: Preparation: B. Kohl et al、EP 166287、eidem、US 4758579 (1986、1988 both to Byk Gluden)、Information available in 2004 indicated that Pantoprazole was used in the manufacture of pharmaceutical preparations in the following countries: Algeria、Argentina、Bahrain、Brazil、Costa Rica、Dominican Republic、El Salvador、Guatemala、Honduras、India、Iraq、Israel、Jordan、Lebanon、Libyan Arab Jamahiriya、Luxembourg、Malaysia、Mexico、Nicaragua、Nigeria、Oman、Panama、Poland、Portugal、Romania、Saudi Arabia、Singapore、Somalia、South Africa、Sudan、Thailand、Tunisia、United Arab Emirates、Yemen (1、2)、Information available in 2004 indicated that Pantoprazole sodium was used in the manufacture of pharmaceutical preparations in the following countries: Argentina、Australia、Austria、Belgium、Canada、Chile、Colombia、Croatia、Czech Republic、Denmark、Ecuador、Finland、France、Germany、Greece、Hong Kong、Hungary、Indonesia、Ireland、Italy、Netherlands、New Zealand、Norway、Slovenia、Spain、Sweden、Switzerland、Turkey、United Kingdom、USA、Yugoslavia (1、Pantoprazole sodium。
泮托拉唑 是一种化工化合物，登记 CAS 号为 102625-70-7，分子式 C16H15F2N3O4S（分子量 383.4）。
登记 CAS 号：102625-70-7
其分子式 C16H15F2N3O4S 由 16 个碳、15 个氢、2 个氟、3 个氮、4 个氧、1 个硫 组成。
别名/同义词：泮托拉唑 · Pantoprazole
泮托拉唑 的 CAS 登记号为 102625-70-7。
分子式 C16H15F2N3O4S，分子量 383.4。
别名/同义词：泮托拉唑、Pantoprazole。
登记用途：Uses: Medication: Antiulcerative、Use (kg、approx.) in Germany (2009): >10000、exact) in Germany (2009): 20548、Use (kg) in USA (2002): 8200、Use (kg) in France (2004): 5287、Consumption (g per capita、approx.) in Germany (2009): 0.122、exact) in Germany (2009): 0.251、Consumption (g per capita) in the USA (2002): 0.0291、Consumption (g per capita) in France (2004): 0.0875、Excretion rate: 0.06、Calculated removal (%): 9.8、Formulations、Preparations: Pantoprazole is available as enteric coated tablets containing 45.1 mg of the sodium salt sesquihydrate equivalent to 40 mg ... of the free anhydrous acid、and as a lyophylisate for iv infusion.、Trade name: Protonix、General Manufacturing Information: Preparation: B. Kohl et al、EP 166287、eidem、US 4758579 (1986、1988 both to Byk Gluden)、Information available in 2004 indicated that Pantoprazole was used in the manufacture of pharmaceutical preparations in the following countries: Algeria、Argentina、Bahrain、Brazil、Costa Rica、Dominican Republic、El Salvador、Guatemala、Honduras、India、Iraq、Israel、Jordan、Lebanon、Libyan Arab Jamahiriya、Luxembourg、Malaysia、Mexico、Nicaragua、Nigeria、Oman、Panama、Poland、Portugal、Romania、Saudi Arabia、Singapore、Somalia、South Africa、Sudan、Thailand、Tunisia、United Arab Emirates、Yemen (1、2)、Information available in 2004 indicated that Pantoprazole sodium was used in the manufacture of pharmaceutical preparations in the following countries: Argentina、Australia、Austria、Belgium、Canada、Chile、Colombia、Croatia、Czech Republic、Denmark、Ecuador、Finland、France、Germany、Greece、Hong Kong、Hungary、Indonesia、Ireland、Italy、Netherlands、New Zealand、Norway、Slovenia、Spain、Sweden、Switzerland、Turkey、United Kingdom、USA、Yugoslavia (1、Pantoprazole sodium。
泮托拉唑（CAS 102625-70-7）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 102625-70-7 |
|---|---|
| PubChem CID | 4679 |
| Molecular formula | C16H15F2N3O4S |
| IUPAC name | 6-(difluoromethoxy)-2-[(3,4-dimethoxy-2-pyridinyl)methylsulfinyl]-1H-benzimidazole |
| UNII (FDA) | D8TST4O562 |
| Molecular Weight | 383.4 |
|---|---|
| XLogP3 | 2.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 7 |
| Exact Mass | 383.07513347 |
| Monoisotopic Mass | 383.07513347 |
| Topological Polar Surface Area | 106 |
| Heavy Atom Count | 26 |
| Boiling Point | 586.9±60.0 °C at 760 mmHg |
|---|---|
| Melting Point | 149-150 |
| Melting Point | 139-140 °C, decomposes |
| LogP | 2.05 |
| LogP | 2.0 |
| Dissociation Constants | pKa1 = 3.92, pKa2 = 8.19 |
| Collision Cross Section | 184.38 Ų [M+H]+ |
| Collision Cross Section | 184.94 Ų [M+Na]+ |
| Collision Cross Section | 188.02 Ų [M-H]- |
pantoprazole; 102625-70-7; Pantozol; Pantoprazol; Pantoprazolum; Pantoloc; BY-1023; SK&F-96022; Altopan; Zovanta; SK&F 96022; SKF-96022; DTXSID4023416; SK-96022; NSC-759257; 6-(difluoromethoxy)-2-[(3,4-dimethoxypyridin-2-yl)methylsulfinyl]-1H-benzimidazole
| Reported hazard statements | H302, H312, H332 (20%), H315 (50%), H319 (40%), H335 (40%), H336 (10%), H341 (10%) |
|---|
H302+H312+H332 (20%): Harmful if swallowed, in contact with skin or if inhaled [Warning Acute toxicity, oral; acute toxicity, dermal; acute toxicity, inhalation]
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
Pantoprazole · CAS 102625-70-7 · C16H15F2N3O4S. UNII D8TST4O562. Boiling Point: 586.9±60.0 °C at 760 mmHg; Melting Point: 149-150; Melting Point: 139-140 °C, decomposes.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Pantoprazole