p-Chlorobenzoic Acid (CAS 74-11-3) — formula C7H5ClO2, molecular weight 156.56; category pharmaceutical intermediates and APIs.
| CAS Number | 74-11-3 |
|---|---|
| Molecular Formula | C7H5ClO2 |
| Molecular Weight | 156.56 |
| Melting Point | 469 °F (NTP, 1992) |
| LogP | 2.65 |
| Applications | Uses: Used as an intermediate (dyes, fungicides, and pharmaceuticals) and preservative (adhesives and paints), [HSDB], Painting (Pigments, Binders, and Biocides) [Category: Paint], Working with Glues and Adhesives [Category: Other], CHEM INT FOR M-CHLOROPHENOL, CHEM INT FOR IODAMIDE (MEDICAL RADIOPAQUE), CHEM INT FOR PLASTICIZERS, Laboratory reagent, manufacture of chemicals, For more Uses (Complete) data for P-CHLOROBENZOIC ACID (6 total), please visit the HSDB record page., Use Classification: Environmental transformation -> Pesticide transformation products (metabolite, successor), Methods of Manufacturing: Preparation by catalytic oxidation of 1-chloro-4-ethylbenzene, ... Manufacture by oxidation of p-chlorobenzaldehyde., Produced by the oxidation of 4-chlorotoluene., U.S. Production: (1979) NOT PRODUCED COMMERCIALLY IN USA, (1981) NOT PRODUCED COMMERCIALLY IN USA, U.S. Imports: (1979) 2.00X10+5 GRAMS (PRINCPL CUSTMS DISTS), (1981) 6.01X10+5 GRAMS (PRINCPL CUSTMS DISTS), General Manufacturing Information: Benzoic acid, 4-chloro-: ACTIVE |
| Category | Pharmaceutical Intermediates |
Documented applications: Uses: Used as an intermediate (dyes, fungicides, and pharmaceuticals) and preservative (adhesives and paints), [HSDB], Painting (Pigments, Binders, and Biocides) [Category: Paint], Working with Glues and Adhesives [Category: Other], CHEM INT FOR M-CHLOROPHENOL, CHEM INT FOR IODAMIDE (MEDICAL RADIOPAQUE), CHEM INT FOR PLASTICIZERS, Laboratory reagent, manufacture of chemicals, For more Uses (Complete) data for P-CHLOROBENZOIC ACID (6 total), please visit the HSDB record page., Use Classification: Environmental transformation -> Pesticide transformation products (metabolite, successor), Methods of Manufacturing: Preparation by catalytic oxidation of 1-chloro-4-ethylbenzene, ... Manufacture by oxidation of p-chlorobenzaldehyde., Produced by the oxidation of 4-chlorotoluene., U.S. Production: (1979) NOT PRODUCED COMMERCIALLY IN USA, (1981) NOT PRODUCED COMMERCIALLY IN USA, U.S. Imports: (1979) 2.00X10+5 GRAMS (PRINCPL CUSTMS DISTS), (1981) 6.01X10+5 GRAMS (PRINCPL CUSTMS DISTS), General Manufacturing Information: Benzoic acid, 4-chloro-: ACTIVE.
p-Chlorobenzoic Acid is a pharmaceutical intermediate or API compound with CAS registry number 74-11-3 and molecular formula C7H5ClO2 (molecular weight 156.56), belonging to the pharmaceutical intermediates and APIs segment of chemical raw materials.
CAS number: 74-11-3
Its molecular formula C7H5ClO2 comprises 7 C, 5 H, 1 Cl, 2 O atoms.
Also known as: p-Chlorobenzoic Acid · 对氯苯甲酸
Category: pharmaceutical intermediates and APIs
The CAS registry number of p-Chlorobenzoic Acid is 74-11-3.
Molecular formula C7H5ClO2, molecular weight 156.56.
It is also registered under: p-Chlorobenzoic Acid, 对氯苯甲酸.
Recorded applications: Uses: Used as an intermediate (dyes, fungicides, and pharmaceuticals) and preservative (adhesives and paints), [HSDB], Painting (Pigments, Binders, and Biocides) [Category: Paint], Working with Glues and Adhesives [Category: Other], CHEM INT FOR M-CHLOROPHENOL, CHEM INT FOR IODAMIDE (MEDICAL RADIOPAQUE), CHEM INT FOR PLASTICIZERS, Laboratory reagent, manufacture of chemicals, For more Uses (Complete) data for P-CHLOROBENZOIC ACID (6 total), please visit the HSDB record page., Use Classification: Environmental transformation -> Pesticide transformation products (metabolite, successor), Methods of Manufacturing: Preparation by catalytic oxidation of 1-chloro-4-ethylbenzene, ... Manufacture by oxidation of p-chlorobenzaldehyde., Produced by the oxidation of 4-chlorotoluene., U.S. Production: (1979) NOT PRODUCED COMMERCIALLY IN USA, (1981) NOT PRODUCED COMMERCIALLY IN USA, U.S. Imports: (1979) 2.00X10+5 GRAMS (PRINCPL CUSTMS DISTS), (1981) 6.01X10+5 GRAMS (PRINCPL CUSTMS DISTS), General Manufacturing Information: Benzoic acid, 4-chloro-: ACTIVE.
Category: Pharmaceutical Intermediates.
Independent reference data for p-Chlorobenzoic Acid (CAS 74-11-3), compiled from public chemistry databases.
| CAS Registry Number | 74-11-3 |
|---|---|
| PubChem CID | 6318 |
| Molecular formula | C7H5ClO2 |
| IUPAC name | 4-chlorobenzoic acid |
| UNII (FDA) | IC7888DF4L |
| Molecular Weight | 156.56 |
|---|---|
| XLogP3 | 2.7 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 1 |
| Exact Mass | 155.9978071 |
| Monoisotopic Mass | 155.9978071 |
| Topological Polar Surface Area | 37.3 |
| Heavy Atom Count | 10 |
| Melting Point | 469 °F (NTP, 1992) |
|---|---|
| Melting Point | 243 |
| Melting Point | 243 °C |
| Flash Point | 238 °C |
| Flash Point | 238 °C (460 °F) (Closed cup) |
| Solubility | 72 |
| Solubility | In water, 77 mg/L at 25 °C |
| Density | 1.5 g/cm³ |
| Vapor Pressure | 0.00233 [mmHg] |
| LogP | 2.65 |
4-Chlorobenzoic acid; 74-11-3; P-CHLOROBENZOIC ACID; Benzoic acid, 4-chloro-; Chlorodracylic acid; p-Chlorbenzoic acid; para-Chlorobenzoic acid; Benzoic acid, p-chloro-; 4-CHLORO-BENZOIC ACID; p-Carboxychlorobenzene; Acido p-clorobenzoico; DTXSID9024772; IC7888DF4L; NSC-32738; DTXCID704772; CHEBI:30747
| GHS notification summary | 26.4% (37 / 140) |
|---|
| GHS notification summary | 26.4% (37 / 140) |
|---|---|
| Reported hazard statements | H301 (20.7%), H302 (52.9%), H315 (49.3%), H319 (64.3%), H335 (42.9%), H411 (20.7%) |
This chemical does not meet GHS hazard criteria for 26.4% (37 of 140) of reports.
H301 (20.7%): Toxic if swallowed [Danger Acute toxicity, oral]
p-Chlorobenzoic Acid · CAS 74-11-3 · C7H5ClO2. UNII IC7888DF4L. Melting Point: 469 °F (NTP, 1992); Melting Point: 243; Melting Point: 243 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 对氯苯甲酸