奥美沙坦（CAS 144689-24-7）：分子式 C24H26N6O3、分子量 446.5。
| CAS号 | 144689-24-7 |
|---|---|
| 分子式 | C24H26N6O3 |
| 分子量 | 446.5 |
| 熔点 | 177.6 |
| 沸点 | 800 |
| LogP | 0.73 |
| 应用领域 | Uses: MEDICATION、Angiotensin II Type 1 Receptor Blockers、Antihypertensive Agents、Methods of Manufacturing: Preparation: H. Yanagisawa et al.、European Patent Office patent 503785、eidem、United States of America patent 5616599 (1992、1997 both to Sankyo).、Formulations、Preparations: Table: Olmesartan Medoxomil Preparations [Table#8198]、Table: Olmesartan Medoxomil Combination Preparations [Table#8199]、Oral: 5 mg、20 mg and 40 mg tablets (Olmetec).、Olmesartan medoxomil |
登记用途：Uses: MEDICATION、Angiotensin II Type 1 Receptor Blockers、Antihypertensive Agents、Methods of Manufacturing: Preparation: H. Yanagisawa et al.、European Patent Office patent 503785、eidem、United States of America patent 5616599 (1992、1997 both to Sankyo).、Formulations、Preparations: Table: Olmesartan Medoxomil Preparations [Table#8198]、Table: Olmesartan Medoxomil Combination Preparations [Table#8199]、Oral: 5 mg、20 mg and 40 mg tablets (Olmetec).、Olmesartan medoxomil。
奥美沙坦 是一种化工化合物，登记 CAS 号为 144689-24-7，分子式 C24H26N6O3（分子量 446.5）。
登记 CAS 号：144689-24-7
其分子式 C24H26N6O3 由 24 个碳、26 个氢、6 个氮、3 个氧 组成。
别名/同义词：奥美沙坦 · Olmesartan
奥美沙坦 的 CAS 登记号为 144689-24-7。
分子式 C24H26N6O3，分子量 446.5。
别名/同义词：奥美沙坦、Olmesartan。
登记用途：Uses: MEDICATION、Angiotensin II Type 1 Receptor Blockers、Antihypertensive Agents、Methods of Manufacturing: Preparation: H. Yanagisawa et al.、European Patent Office patent 503785、eidem、United States of America patent 5616599 (1992、1997 both to Sankyo).、Formulations、Preparations: Table: Olmesartan Medoxomil Preparations [Table#8198]、Table: Olmesartan Medoxomil Combination Preparations [Table#8199]、Oral: 5 mg、20 mg and 40 mg tablets (Olmetec).、Olmesartan medoxomil。
奥美沙坦（CAS 144689-24-7）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 144689-24-7 |
|---|---|
| PubChem CID | 158781 |
| Molecular formula | C24H26N6O3 |
| IUPAC name | 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid |
| UNII (FDA) | 8W1IQP3U10 |
| Molecular Weight | 446.5 |
|---|---|
| XLogP3 | 3.2 |
| Hydrogen Bond Donor Count | 3 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 8 |
| Exact Mass | 446.20663871 |
| Monoisotopic Mass | 446.20663871 |
| Topological Polar Surface Area | 130 |
| Heavy Atom Count | 33 |
| Boiling Point | 800 |
|---|---|
| Melting Point | 177.6 |
| Melting Point | 175 - 180 °C |
| Solubility | 1.05e-02 g/L |
| LogP | 0.73 |
| LogP | 5.9 |
| Dissociation Constants | 4.3 |
Olmesartan; 144689-24-7; RNH-6270; omesartan; NSC-759810; 8W1IQP3U10; DTXSID2040571; CHEBI:48416; olmesartanum; olmesartanum medoxomilum; RefChem:55770; DTXCID0020571; Olmesartan Acid; 5-(2-hydroxypropan-2-yl)-2-propyl-3-[[4-[2-(2H-tetrazol-5-yl)phenyl]phenyl]methyl]imidazole-4-carboxylic acid; CS-088; MFCD00914967
| GHS notification summary | 33.3% (1 / 3) |
|---|
| GHS notification summary | 33.3% (1 / 3) |
|---|---|
| Reported hazard statements | H302 (66.7%), H312 (66.7%), H315 (33.3%), H319 (33.3%), H332 (66.7%), H335 (33.3%) |
This chemical does not meet GHS hazard criteria for 33.3% (1 of 3) of reports.
H302 (66.7%): Harmful if swallowed [Warning Acute toxicity, oral]
Olmesartan · CAS 144689-24-7 · C24H26N6O3. UNII 8W1IQP3U10. Boiling Point: 800; Melting Point: 177.6; Melting Point: 175 - 180 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Olmesartan