制霉菌素二水合物

制霉菌素二水合物（CAS 1400-61-9）：分子式 C47H75NO17、分子量 926.1。

产品概览

应用领域

登记用途：Uses: MEDICATION (VET)、MEDICATION、An experimental teratogen. An anti-biotic、Antimycotic polyene antibiotic... for local treatment of vulvovaginal candidiasis (monoliasis).、Medicine (antifungal antibiotics)、feed additive、Use (kg、approx.) in Germany (2009): >7500、Use (kg) in USA (2002): 250、Consumption (g per capita、approx.) in Germany (2009): 0.0916、Consumption (g per capita) in the USA (2002): 0.000886、Excretion rate: 1、Calculated removal (%): 75.1、Used to treat cutaneous、vaginal、mucosal and esophageal Candida infections. Nystatin is often used as prophylaxis in patients who are at risk for fungal infections、such as AIDS patients with a low CD4+ count and patients receiving chemotherapy.[Wikipedia]、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Veterinary Drug -> ANTIFUNGAL_AGENT -> JECFA Functional Classes、Methods of Manufacturing: Vandeputte、US patent 2、832、719 (1958 to Olin Mathieson)、Renella、US patent 3、517、100 (1970 to American Cyanamid)、Polyene antifungal antibiotic complex containing 3 biologically active compounds、A1、A2、A3. Produced by Streptomyces noursei、S. aureus and other Streptomyces spp.、Formulations、Preparations: Tablets、dragees、lozenges、suspensions、drops、ointments、powders、gels、creams、ovulas、and vaginal tablets of different concentrations. There are also formulations available in combination with antibiotics and、or steroids such as tetracycline、neomycin、gramicidin、and cortisone. Dosages are often expressed in IE (100 000 IE = 22.73 mg nystatin A1).、Trade Names: Adiclair (Ardeypharm)、Biofanal (Pfleger)、Candex (Dome)、Candio-Hermal (Hermal、Merck)、Canstat (Lederle)、Diastatin (Pfizer)、Fungicidin (Spofa)、Fungireduct (Azupharma)、Herniocid (Mayrhofer)、Korostatin (Holland-Rantos)、Lederlind (Lederle)、Lystin (Mekim)、Mikostatin (Squibb)、Moronal (Heyden、Squibb)、Multilind (Bristol-Myers Squibb、Fair)、Mycostatin (Bristol-Myers Squibb、Heyden、Sanofi Winthrop、Westwood-Squibb)、Mykinac (NMC)、MycoPosterine N (Kade)、Mykundex (Jossa)、Nadostine (Pan-Well)、Nilstat (Lederle)、Nyaderm (Taro)、Nysert (Norwich Eaton)、Nystacid (Farmos Group)、Nystaderm (Dermapharm)、Nysta-Dome (Dome)、Nystan (Squibb)、Nystat-Rx (Pharma-Tek)、Nystavescent (Squibb)、Nystex (Savage)、Oranyst (Taro)、O-V Statin (Squibb)、Restatin (Remedica)、Rivostatin (Rivopharm) Stereomycin (Medica).、Nystatin is commercially available as a cream、ointment、or powder for topical application to the skin、as a powder for oral suspension、oral suspension、or film-coated tablets for oral administration、as oral lozenges for oral topical administration、and as tablets for intravaginal administration.、Oral: For suspension 50 million units Nystatin Powder、Paddock Nystat-Rx、(Pharma-Tek)、150 million units Nystatin Powder、500 million units Nystatin Powder、1 billion units Nystat-Rx、2 billion units Nystatin Powder、(Paddock)、5 billion units Nystatin Powder、(Paddock). Oral: Suspension: 100、000 units、mL Mycostatin ( with =1% alcohol parabens and sucrose 50%)、(Bristol-Myers Squibb). Oral: Tablets、film-coated 500、000 units Mycostatin Filmlok ( with povidone)、(Bristol-Myers Squibb)、General Manufacturing Information: Nystatin is now known to be a mixture but composition has not been completely elucidated. Nystatin A [34786-70-4] C47-H75-N-O17 is closely related to Amphotericin B. Each is a macrocyclic lactone containing a ketal ring、an all-trans polyene system、and a mycosamine (3-amino-3-deoxyrhamnose) moiety.、Used、mostly as antifungal feed additive in control or treatment of crop ... US feed additive regulations use 2、800 units、mg. ... US regulations established zero tolerance for its residue in or on uncooked tissues or by-products (including eggs) of treated animals or poultry if used for human consumption.、Used as food additive permitted in feed and drinking water of animals and ... also permitted in food for human consumption.、Nystatin was found in the mycelium of Streptomyces noursei in 1950 and produced on an industrial scale by Squibb & Sons Co. in 1954. This antibiotic was used orally and topically as the first clinically applied polyene macrolide with antifungal properties.。

技术档案

这个产品是什么

制霉菌素二水合物 是一种化工化合物，登记 CAS 号为 1400-61-9，分子式 C47H75NO17（分子量 926.1）。

识别信息

登记 CAS 号：1400-61-9

其分子式 C47H75NO17 由 47 个碳、75 个氢、1 个氮、17 个氧 组成。

别名/同义词：制霉菌素二水合物 · nystatin dihydrate

常见问题

PubChem 公开数据