去甲替林（CAS 72-69-5）：分子式 C19H21N、分子量 263.4。
| CAS号 | 72-69-5 |
|---|---|
| 分子式 | C19H21N |
| 分子量 | 263.4 |
| 熔点 | 58 |
| 沸点 | 396.62 |
| LogP | 3.9 |
| 应用领域 | Uses: MEDICATION、Adrenergic Uptake Inhibitors、Antidepressive Agents、Tricyclic、Use (kg、approx.) in Germany (2009): >100、Use (kg) in USA (2002): 2930、Consumption (g per capita、approx.) in Germany (2009): 0.00122、Consumption (g per capita) in the USA (2002): 0.0104、Calculated removal (%): 86.6、For the treatment of depression、chronic pain、irritable bowel syndrome、sleep disorders、diabetic neuropathy、agitation and insomnia、and migraine prophylaxis.、Use Classification: Pharmaceuticals、Pharmaceuticals -> Transformation products、Methods of Manufacturing: Dibenzosuberone + cyclopropyl bromide + methylamine (Grignard reaction、rearrangement、amine formation)、Formulations、Preparations: Table: Nortriptyline Hydrochloride Preparations [Table#4557]、Acetexa、Allegron、Aventyl、Noritren、Nortrilen、Pamelor、Sensaval、Vividyl.、Nortriptyline hydrochloride、General Manufacturing Information: The product is available as the free base or hydrochloride. |
登记用途：Uses: MEDICATION、Adrenergic Uptake Inhibitors、Antidepressive Agents、Tricyclic、Use (kg、approx.) in Germany (2009): >100、Use (kg) in USA (2002): 2930、Consumption (g per capita、approx.) in Germany (2009): 0.00122、Consumption (g per capita) in the USA (2002): 0.0104、Calculated removal (%): 86.6、For the treatment of depression、chronic pain、irritable bowel syndrome、sleep disorders、diabetic neuropathy、agitation and insomnia、and migraine prophylaxis.、Use Classification: Pharmaceuticals、Pharmaceuticals -> Transformation products、Methods of Manufacturing: Dibenzosuberone + cyclopropyl bromide + methylamine (Grignard reaction、rearrangement、amine formation)、Formulations、Preparations: Table: Nortriptyline Hydrochloride Preparations [Table#4557]、Acetexa、Allegron、Aventyl、Noritren、Nortrilen、Pamelor、Sensaval、Vividyl.、Nortriptyline hydrochloride、General Manufacturing Information: The product is available as the free base or hydrochloride.。
去甲替林 是一种化工化合物，登记 CAS 号为 72-69-5，分子式 C19H21N（分子量 263.4）。
登记 CAS 号：72-69-5
其分子式 C19H21N 由 19 个碳、21 个氢、1 个氮 组成。
别名/同义词：去甲替林 · nortriptyline
去甲替林 的 CAS 登记号为 72-69-5。
分子式 C19H21N，分子量 263.4。
别名/同义词：去甲替林、nortriptyline。
登记用途：Uses: MEDICATION、Adrenergic Uptake Inhibitors、Antidepressive Agents、Tricyclic、Use (kg、approx.) in Germany (2009): >100、Use (kg) in USA (2002): 2930、Consumption (g per capita、approx.) in Germany (2009): 0.00122、Consumption (g per capita) in the USA (2002): 0.0104、Calculated removal (%): 86.6、For the treatment of depression、chronic pain、irritable bowel syndrome、sleep disorders、diabetic neuropathy、agitation and insomnia、and migraine prophylaxis.、Use Classification: Pharmaceuticals、Pharmaceuticals -> Transformation products、Methods of Manufacturing: Dibenzosuberone + cyclopropyl bromide + methylamine (Grignard reaction、rearrangement、amine formation)、Formulations、Preparations: Table: Nortriptyline Hydrochloride Preparations [Table#4557]、Acetexa、Allegron、Aventyl、Noritren、Nortrilen、Pamelor、Sensaval、Vividyl.、Nortriptyline hydrochloride、General Manufacturing Information: The product is available as the free base or hydrochloride.。
去甲替林（CAS 72-69-5）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 72-69-5 |
|---|---|
| PubChem CID | 4543 |
| Molecular formula | C19H21N |
| IUPAC name | N-methyl-3-(2-tricyclo[9.4.0.03,8]pentadeca-1(15),3,5,7,11,13-hexaenylidene)propan-1-amine |
| UNII (FDA) | BL03SY4LXB |
| Molecular Weight | 263.4 |
|---|---|
| XLogP3 | 4.5 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 3 |
| Exact Mass | 263.167399674 |
| Monoisotopic Mass | 263.167399674 |
| Topological Polar Surface Area | 12 |
| Heavy Atom Count | 20 |
| Boiling Point | 396.62 |
|---|---|
| Melting Point | 58 |
| Melting Point | 213 - 215 °C |
| Solubility | 0.00087 |
| Solubility | 8.74e-04 g/L |
| LogP | 3.9 |
| LogP | log Kow = 4.51 |
| LogP | 4.7 |
| LogP | 4.4 |
| Dissociation Constants | 10.13 |
nortriptyline; 72-69-5; Noramitriptyline; Desitriptilina; Ateben; Avantyl; Lumbeck; Desmethylamitriptyline; Noritren; Sensaval; Demethylamitriptyline; Sesaval; Demethylamitryptyline; Nortryptiline; Nortryptyline; Nortrilen
| Reported hazard statements | H302 (100%) |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
P264, P270, P301+P317, P330, and P501 (click each P-code to see the statement)
nortriptyline · CAS 72-69-5 · C19H21N. UNII BL03SY4LXB. Boiling Point: 396.62; Melting Point: 58; Melting Point: 213 - 215 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: nortriptyline