Nilotinib & its intermediates (CAS 641571-10-0) — formula C28H22F3N7O, molecular weight 529.5; category chemical intermediates.
Nilotinib & its intermediates (CAS 641571-10-0) is a chemical raw material in the chemical intermediates category. Its molecular formula C28H22F3N7O comprises 28 C, 22 H, 3 F, 7 N, 1 O atoms. Its molecular weight is about 529.5. Reported physicochemical data: LogP about 4.9. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 641571-10-0 |
|---|---|
| Molecular Formula | C28H22F3N7O |
| Molecular Weight | 529.5 |
| LogP | 4.9 |
| Applications | MEDICATION, Use (kg, approx.) in Germany (2009): >75, Consumption (g per capita, approx.) in Germany (2009): 0.000916, Calculated removal (%): 78 |
| Category | Chemical Intermediates |
Documented applications: MEDICATION, Use (kg, approx.) in Germany (2009): >75, Consumption (g per capita, approx.) in Germany (2009): 0.000916, Calculated removal (%): 78.
Nilotinib & its intermediates is a chemical intermediate compound with CAS registry number 641571-10-0 and molecular formula C28H22F3N7O (molecular weight 529.5), belonging to the chemical intermediates segment of chemical raw materials.
CAS number: 641571-10-0
Its molecular formula C28H22F3N7O comprises 28 C, 22 H, 3 F, 7 N, 1 O atoms.
Also known as: Nilotinib & its intermediates · 尼罗替尼及其中间体
Category: chemical intermediates
The CAS registry number of Nilotinib & its intermediates is 641571-10-0.
Molecular formula C28H22F3N7O, molecular weight 529.5.
It is also registered under: Nilotinib & its intermediates, 尼罗替尼及其中间体.
Recorded applications: MEDICATION, Use (kg, approx.) in Germany (2009): >75, Consumption (g per capita, approx.) in Germany (2009): 0.000916, Calculated removal (%): 78.
Category: Chemical Intermediates.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Nilotinib & its intermediates (CAS 641571-10-0), compiled from public chemistry databases.
| CAS Registry Number | 641571-10-0 |
|---|---|
| PubChem CID | 644241 |
| Molecular formula | C28H22F3N7O |
| IUPAC name | 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]benzamide |
| UNII (FDA) | F41401512X |
| Molecular Weight | 529.5 |
|---|---|
| XLogP3 | 4.9 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 9 |
| Rotatable Bond Count | 6 |
| Exact Mass | 529.18379284 |
| Monoisotopic Mass | 529.18379284 |
| Topological Polar Surface Area | 97.6 |
| Heavy Atom Count | 39 |
| Solubility | 2.01e-03 g/L |
|---|---|
| Dissociation Constants | pKa1 = 2.1; pKa2 = 5.4 |
Nilotinib; 641571-10-0; AMN 107; AMN-107; nilotinibum; Danziten; NSC-747599; DTXSID5042663; F41401512X; CHEBI:52172; RefChem:58968; AMN 107 Base; DTXCID3022663; L01XE08; Tasigna; AMN107
| Reported hazard statements | H361 (69.2%), H372 (15.4%), H373 (76.9%), H400 (69.2%), H410 (69.2%), H413 (23.1%) |
|---|
H361 (69.2%): Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity]
H361fd (46.2%): Suspected of damaging fertility; Suspected of damaging the unborn child [Warning Reproductive toxicity]
Nilotinib & its intermediates · CAS 641571-10-0 · C28H22F3N7O. UNII F41401512X. Solubility: 2.01e-03 g/L; Dissociation Constants: pKa1 = 2.1; pKa2 = 5.4.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 尼罗替尼及其中间体