新霉素（CAS 11004-65-2）：分子式 C23H46N6O13、分子量 614.6。
| CAS号 | 11004-65-2 |
|---|---|
| 分子式 | C23H46N6O13 |
| 分子量 | 614.6 |
| 熔点 | 6 °C (sulfate form) |
| LogP | -7.8 |
| 应用领域 | Uses: For neomycin (USEPA、OPP Pesticide Code: 006303) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、Broad-spectrum antibiotic、... Used for bladder irrigation ... to prevent bacteriuria and bacteremia associated with the use of indwelling catheters.、Veterinary bactericidal drug、For more Uses (Complete) data for Neomycin (7 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >25、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Calculated removal (%): 92.1、Topical uses include treatment for superficial eye infections caused by susceptible bacteria (used in combination with other antiinfectives)、treatment of otitis externa caused by susceptible bacteria、treatment or prevention of bacterial infections in skin lesions、and use as a continuous short-term irrigant or rinse to prevent bacteriuria and gram negative rod bacteremia in abacteriuric patients with indwelling catheters. May be used orally to treat hepatic encephalopathy、as a perioperative prophylactic agent、and as an adjunct to fluid and electrolyte replacement in the treatment of diarrhea caused to enteropathogenic E. coli (EPEC).、Use Classification: Veterinary Drug -> ANTIMICROBIAL_AGENT -> JECFA Functional Classes、Methods of Manufacturing: Produced by Streptomyces fradiae.、Antibiotics can broadly be classified into the following categories: aminoglycosides、beta-lactams、macrolides、and tetracyclines、of which only the tetracylines do not use ion-exchange resins in their recovery from fermentation broths.、Ion-exchange resins、Formulations、Preparations: Table: Neomycin Sulfate Preparations [Table#4505]、Table: Neomycin Sulfate Combinations Preparations [Table#4506]、Bulk: Powder: Neo-Rx Micronized Antibiotic Powder for Prescription Compounding (Pharma-Tek).、Neomycin sulfate、Urogenital: For irrigation、concentrate、sterile: 57 mg Neosporin Sulfate (40 mg of neomycin) per mL and Polymyxin B Sulfate 200、000 units (of polymyxin B) per mL、Neosporin G.U. Irrigant (Monarch).、For more Formulations、Preparations (Complete) data for Neomycin (12 total)、General Manufacturing Information: Antibiotic complex composed of of neomycins A、B、and C.、Neomycin is a mixture of neomycin B (119-04-0) ... and neomycin C (66-86-4) ... Neomycin B is the main component. |
登记用途：Uses: For neomycin (USEPA、OPP Pesticide Code: 006303) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、Broad-spectrum antibiotic、... Used for bladder irrigation ... to prevent bacteriuria and bacteremia associated with the use of indwelling catheters.、Veterinary bactericidal drug、For more Uses (Complete) data for Neomycin (7 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >25、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Calculated removal (%): 92.1、Topical uses include treatment for superficial eye infections caused by susceptible bacteria (used in combination with other antiinfectives)、treatment of otitis externa caused by susceptible bacteria、treatment or prevention of bacterial infections in skin lesions、and use as a continuous short-term irrigant or rinse to prevent bacteriuria and gram negative rod bacteremia in abacteriuric patients with indwelling catheters. May be used orally to treat hepatic encephalopathy、as a perioperative prophylactic agent、and as an adjunct to fluid and electrolyte replacement in the treatment of diarrhea caused to enteropathogenic E. coli (EPEC).、Use Classification: Veterinary Drug -> ANTIMICROBIAL_AGENT -> JECFA Functional Classes、Methods of Manufacturing: Produced by Streptomyces fradiae.、Antibiotics can broadly be classified into the following categories: aminoglycosides、beta-lactams、macrolides、and tetracyclines、of which only the tetracylines do not use ion-exchange resins in their recovery from fermentation broths.、Ion-exchange resins、Formulations、Preparations: Table: Neomycin Sulfate Preparations [Table#4505]、Table: Neomycin Sulfate Combinations Preparations [Table#4506]、Bulk: Powder: Neo-Rx Micronized Antibiotic Powder for Prescription Compounding (Pharma-Tek).、Neomycin sulfate、Urogenital: For irrigation、concentrate、sterile: 57 mg Neosporin Sulfate (40 mg of neomycin) per mL and Polymyxin B Sulfate 200、000 units (of polymyxin B) per mL、Neosporin G.U. Irrigant (Monarch).、For more Formulations、Preparations (Complete) data for Neomycin (12 total)、General Manufacturing Information: Antibiotic complex composed of of neomycins A、B、and C.、Neomycin is a mixture of neomycin B (119-04-0) ... and neomycin C (66-86-4) ... Neomycin B is the main component.。
新霉素 是一种化工化合物，登记 CAS 号为 11004-65-2，分子式 C23H46N6O13（分子量 614.6）。
登记 CAS 号：11004-65-2
其分子式 C23H46N6O13 由 23 个碳、46 个氢、6 个氮、13 个氧 组成。
别名/同义词：新霉素 · Neomycin
新霉素 的 CAS 登记号为 11004-65-2。
分子式 C23H46N6O13，分子量 614.6。
别名/同义词：新霉素、Neomycin。
登记用途：Uses: For neomycin (USEPA、OPP Pesticide Code: 006303) there are 0 labels match.、SRP: Not registered for current use in the U.S.、but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、Broad-spectrum antibiotic、... Used for bladder irrigation ... to prevent bacteriuria and bacteremia associated with the use of indwelling catheters.、Veterinary bactericidal drug、For more Uses (Complete) data for Neomycin (7 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >25、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Calculated removal (%): 92.1、Topical uses include treatment for superficial eye infections caused by susceptible bacteria (used in combination with other antiinfectives)、treatment of otitis externa caused by susceptible bacteria、treatment or prevention of bacterial infections in skin lesions、and use as a continuous short-term irrigant or rinse to prevent bacteriuria and gram negative rod bacteremia in abacteriuric patients with indwelling catheters. May be used orally to treat hepatic encephalopathy、as a perioperative prophylactic agent、and as an adjunct to fluid and electrolyte replacement in the treatment of diarrhea caused to enteropathogenic E. coli (EPEC).、Use Classification: Veterinary Drug -> ANTIMICROBIAL_AGENT -> JECFA Functional Classes、Methods of Manufacturing: Produced by Streptomyces fradiae.、Antibiotics can broadly be classified into the following categories: aminoglycosides、beta-lactams、macrolides、and tetracyclines、of which only the tetracylines do not use ion-exchange resins in their recovery from fermentation broths.、Ion-exchange resins、Formulations、Preparations: Table: Neomycin Sulfate Preparations [Table#4505]、Table: Neomycin Sulfate Combinations Preparations [Table#4506]、Bulk: Powder: Neo-Rx Micronized Antibiotic Powder for Prescription Compounding (Pharma-Tek).、Neomycin sulfate、Urogenital: For irrigation、concentrate、sterile: 57 mg Neosporin Sulfate (40 mg of neomycin) per mL and Polymyxin B Sulfate 200、000 units (of polymyxin B) per mL、Neosporin G.U. Irrigant (Monarch).、For more Formulations、Preparations (Complete) data for Neomycin (12 total)、General Manufacturing Information: Antibiotic complex composed of of neomycins A、B、and C.、Neomycin is a mixture of neomycin B (119-04-0) ... and neomycin C (66-86-4) ... Neomycin B is the main component.。
新霉素（CAS 11004-65-2）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 11004-65-2 |
|---|---|
| PubChem CID | 8378 |
| Molecular formula | C23H46N6O13 |
| IUPAC name | (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol |
| UNII (FDA) | 4BOC774388 |
| Molecular Weight | 614.6 |
|---|---|
| XLogP3 | -9 |
| Hydrogen Bond Donor Count | 13 |
| Hydrogen Bond Acceptor Count | 19 |
| Rotatable Bond Count | 9 |
| Exact Mass | 614.31228554 |
| Monoisotopic Mass | 614.31228554 |
| Topological Polar Surface Area | 353 |
| Heavy Atom Count | 42 |
| Melting Point | 6 °C (sulfate form) |
|---|---|
| Solubility | 6.47e+01 g/L |
| LogP | -7.8 |
| LogP | log Kow = -3.70 |
| Dissociation Constants | pKa = 12.9; pKb = 9.52 (25 °C) |
neomycin; Fradiomycin; Neomas; Nivemycin; Myacyne; Neolate; Caswell No. 595; Vonamycin powder V; Neomin; Neomicina; Neomycine; Neomycinum; 1404-04-2; PIMAVECORT; I16QD7X297; VONAMYCIN
| Regulatory & Food Contact | ANTIMICROBIAL_AGENT: Veterinary Drug 0â60 μg/kg bw TRS 918-JECFA 60/5 FAS 51-JECFA 60/3 |
|---|
| Reported hazard statements | H302 (100%), H317 (100%), H334 (100%), H332 (15.4%), H361 (84.6%), H373 (76.9%) |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]
Neomycin · CAS 11004-65-2 · C23H46N6O13. UNII 4BOC774388. Melting Point: 6 °C (sulfate form); Solubility: 6.47e+01 g/L; LogP: -7.8.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Neomycin