纳美芬（CAS 55096-26-9）：分子式 C21H25NO3、分子量 339.4。
| CAS号 | 55096-26-9 |
|---|---|
| 分子式 | C21H25NO3 |
| 分子量 | 339.4 |
| 熔点 | 105-110 °C |
| LogP | 2.7 |
| 应用领域 | Uses: Is a pure opioid receptor antagonist ... used to reverse opioid intoxication and for the treatment of opioid dependence. The compound is in clinical development for the treatment of alcoholism、to support smoking cessation and to control pathological gambling.、Therapeutic Category: Narcotic antagonist、Therapeutic Category (Vet): Narcotic antagonist、MEDICATION、Methods of Manufacturing: Nalmefene is synthesized by a Wittig reaction of naltrexone with triphenylmethylphosphonium bromide in DMSO under basic catalysis of NaH.、Preparation: J. Fishman、US 3814768 (1974 to M.J. Lewenstein)、Formulations、Preparations: Nalmetrene、REVEX、General Manufacturing Information: Nalmafene is a relatively pure mu-receptor antagonist that is more potent than naloxone. |
登记用途：Uses: Is a pure opioid receptor antagonist ... used to reverse opioid intoxication and for the treatment of opioid dependence. The compound is in clinical development for the treatment of alcoholism、to support smoking cessation and to control pathological gambling.、Therapeutic Category: Narcotic antagonist、Therapeutic Category (Vet): Narcotic antagonist、MEDICATION、Methods of Manufacturing: Nalmefene is synthesized by a Wittig reaction of naltrexone with triphenylmethylphosphonium bromide in DMSO under basic catalysis of NaH.、Preparation: J. Fishman、US 3814768 (1974 to M.J. Lewenstein)、Formulations、Preparations: Nalmetrene、REVEX、General Manufacturing Information: Nalmafene is a relatively pure mu-receptor antagonist that is more potent than naloxone.。
纳美芬 是一种化工化合物，登记 CAS 号为 55096-26-9，分子式 C21H25NO3（分子量 339.4）。
登记 CAS 号：55096-26-9
其分子式 C21H25NO3 由 21 个碳、25 个氢、1 个氮、3 个氧 组成。
别名/同义词：纳美芬 · nalmefene
纳美芬 的 CAS 登记号为 55096-26-9。
分子式 C21H25NO3，分子量 339.4。
别名/同义词：纳美芬、nalmefene。
登记用途：Uses: Is a pure opioid receptor antagonist ... used to reverse opioid intoxication and for the treatment of opioid dependence. The compound is in clinical development for the treatment of alcoholism、to support smoking cessation and to control pathological gambling.、Therapeutic Category: Narcotic antagonist、Therapeutic Category (Vet): Narcotic antagonist、MEDICATION、Methods of Manufacturing: Nalmefene is synthesized by a Wittig reaction of naltrexone with triphenylmethylphosphonium bromide in DMSO under basic catalysis of NaH.、Preparation: J. Fishman、US 3814768 (1974 to M.J. Lewenstein)、Formulations、Preparations: Nalmetrene、REVEX、General Manufacturing Information: Nalmafene is a relatively pure mu-receptor antagonist that is more potent than naloxone.。
纳美芬（CAS 55096-26-9）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 55096-26-9 |
|---|---|
| PubChem CID | 5284594 |
| Molecular formula | C21H25NO3 |
| IUPAC name | (4R,4aS,7aS,12bS)-3-(cyclopropylmethyl)-7-methylidene-2,4,5,6,7a,13-hexahydro-1H-4,12-methanobenzofuro[3,2-e]isoquinoline-4a,9-diol |
| UNII (FDA) | TOV02TDP9I |
| Molecular Weight | 339.4 |
|---|---|
| XLogP3 | 2.7 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 2 |
| Exact Mass | 339.18344366 |
| Monoisotopic Mass | 339.18344366 |
| Topological Polar Surface Area | 52.9 |
| Heavy Atom Count | 25 |
| Melting Point | 105-110 °C |
|---|---|
| Dissociation Constants | 7.6 |
nalmefene; Nalmetrene; 55096-26-9; Nalmefeno; ORF-11676; Nalmefenum; ORF 11676; DTXSID8023347; TOV02TDP9I; SRD174; JKB-121; SRD-174; ORF 1167; ORF-1167; (5alpha)-17-(Cyclopropylmethyl)-4,5-epoxy-6-methylenemorphinon-3,14-diol; DTXCID903347
| Reported hazard statements | H315 (97.5%), H319 (97.5%), H335 (97.5%) |
|---|
H315 (97.5%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (97.5%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
nalmefene · CAS 55096-26-9 · C21H25NO3. UNII TOV02TDP9I. Melting Point: 105-110 °C; Dissociation Constants: 7.6.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: nalmefene