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N-Vinyl-2-pyrrolidone

CAS 88-12-0C6H9NOMW 111.07 g/mol

N-Vinyl-2-pyrrolidone (CAS 88-12-0) — formula C6H9NO, molecular weight 111.07 g/mol.

Product Overview

CAS Number88-12-0
Molecular FormulaC6H9NO
Molecular Weight111.07 g/mol
Melting Point13 °C
Boiling Point96 °C @ 14 mm Hg; 193 °C @ 400 mm Hg
LogP0.4
ApplicationsUses: Used as a monomer in the production of polyvinyl pyrrolidone, also used in the production of other polymers and organic chemicals, [ACGIH], Using Disinfectants or Biocides [Category: Clean], Plastic Composites Manufacturing [Category: Industry], Used to manufacture water-soluble and insoluble forms of polyvinyl pyrrolidone for pharmaceutical and cosmetic industries and to make copolymers with other monomers intended for use in contact with food. ...Used in cast films adherent to glass, metals, plastics., Solvent for resins, co-monomer for polymerization, binder in cosmetic and pharmaceutical preparations., ...About 10-15% of the monomer is used in the pharmaceutical industry for the production of PVP-iodine complex used as a disinfectant. It is also used as a reactive solvent of UV-curable resins for the production of printing inks and paints as paper and textile auxiliaries, and as an additive in the cosmetics industry., ... Precursor and intermediate for process auxiliaries and additives. The main areas of use are the production of polyvinylpyrrolidone and copolymers, the preferred comonomers being vinyl acetate and methyl acrylate., For more Uses (Complete) data for 2-PYRROLIDINONE, 1-ETHENYL- (6 total), please visit the HSDB record page., Use Classification: Cosmetics -> Film forming, Binding, Antistatic, Emulsion stabilizing, Hair fixing, Industry Uses: Monomers, Adhesion, cohesion promoter, Intermediate, Not Known or Reasonably Ascertainable, Consumer Uses: Adhesion, Household Products: Information on 179 consumer products that contain Polyvinylpyrrolidone (PVP) in the following categories is provided:, • Commercial, Institutional, • Inside the Home, • Personal Care, • Pet Care, Methods of Manufacturing: Industrially, NVP is produced by reacting 2-pyrrolidone with acetylene in high-pressure autoclaves at 130-160 °C and pressures of up to 2.6 MPa. Vinylation proceeds in the liquid phase and is catalyzed by 2-pyrrolidone-potassium, which is obtained by dissolving 1-5% potassium hydroxide (the water formed is removed by distillation in vacuo) or potassium in 2-pyrrolidone. To avoid the danger of explosions acetylene-nitrogen mixtures are used instead of acetylene. The crude product obtained by continuous or batch production is purified by vacuum distillation., Formulations, Preparations: A typical commercial product has the following composition: NVP content, minimum 99 weight percent, 2-pyrrolidone, maximum 0.2 weight percent, water, maximum 0.1 weight percent, color index (freshly filled, APHA), 40 maximum, stabilizers: 10 ppm N, N'-bis(1-methylpropyl)-1, 4-benzenediamine or 0.1 weight percent sodium hydroxide., Polyquaternium-11 is a copolymer of vinylpyrrolidone and dimethylamine ethylmethacrylate, partially quaternized with diethyl sulfate....Industry specifications for Polyquaternium-11 allow residual vinylpyrrolidone to a maximum concentration of 1.0%. ...The principal use of Polyquaternium-11 in cosmetic products is in hair care preparations., Polyvinylpyrrolidone, Vinyl Acetate Copolymer (PVP, VA Copolymer) is the copolymer of vinyl pyrrolidone (VP) and vinyl acetate (VA) monomers. The copolymers vary in their ratio of VP to VA and range from 70:30 to 30:70 VP to VA., U.S. Production: 2023: 55, 000, 000 - <70, 000 lb, 2022: 55, 2021: 55, 2020: 55, General Manufacturing Information: Printing Ink Manufacturing, All Other Basic Organic Chemical Manufacturing, Adhesive Manufacturing, All Other Chemical Product and Preparation Manufacturing, 2-Pyrrolidinone, 1-ethenyl-: ACTIVE, PVP, VA Copolymer is used in tablet coating, spray bandages, protective masks, spray or rub-on gloves, plant leaf sprays, shoe polishes, and film production, it is also used as a dye medium in adhesive sticks and in the synthesis of peptides.

Applications

Documented applications: Uses: Used as a monomer in the production of polyvinyl pyrrolidone, also used in the production of other polymers and organic chemicals, [ACGIH], Using Disinfectants or Biocides [Category: Clean], Plastic Composites Manufacturing [Category: Industry], Used to manufacture water-soluble and insoluble forms of polyvinyl pyrrolidone for pharmaceutical and cosmetic industries and to make copolymers with other monomers intended for use in contact with food. ...Used in cast films adherent to glass, metals, plastics., Solvent for resins, co-monomer for polymerization, binder in cosmetic and pharmaceutical preparations., ...About 10-15% of the monomer is used in the pharmaceutical industry for the production of PVP-iodine complex used as a disinfectant. It is also used as a reactive solvent of UV-curable resins for the production of printing inks and paints as paper and textile auxiliaries, and as an additive in the cosmetics industry., ... Precursor and intermediate for process auxiliaries and additives. The main areas of use are the production of polyvinylpyrrolidone and copolymers, the preferred comonomers being vinyl acetate and methyl acrylate., For more Uses (Complete) data for 2-PYRROLIDINONE, 1-ETHENYL- (6 total), please visit the HSDB record page., Use Classification: Cosmetics -> Film forming, Binding, Antistatic, Emulsion stabilizing, Hair fixing, Industry Uses: Monomers, Adhesion, cohesion promoter, Intermediate, Not Known or Reasonably Ascertainable, Consumer Uses: Adhesion, Household Products: Information on 179 consumer products that contain Polyvinylpyrrolidone (PVP) in the following categories is provided:, • Commercial, Institutional, • Inside the Home, • Personal Care, • Pet Care, Methods of Manufacturing: Industrially, NVP is produced by reacting 2-pyrrolidone with acetylene in high-pressure autoclaves at 130-160 °C and pressures of up to 2.6 MPa. Vinylation proceeds in the liquid phase and is catalyzed by 2-pyrrolidone-potassium, which is obtained by dissolving 1-5% potassium hydroxide (the water formed is removed by distillation in vacuo) or potassium in 2-pyrrolidone. To avoid the danger of explosions acetylene-nitrogen mixtures are used instead of acetylene. The crude product obtained by continuous or batch production is purified by vacuum distillation., Formulations, Preparations: A typical commercial product has the following composition: NVP content, minimum 99 weight percent, 2-pyrrolidone, maximum 0.2 weight percent, water, maximum 0.1 weight percent, color index (freshly filled, APHA), 40 maximum, stabilizers: 10 ppm N, N'-bis(1-methylpropyl)-1, 4-benzenediamine or 0.1 weight percent sodium hydroxide., Polyquaternium-11 is a copolymer of vinylpyrrolidone and dimethylamine ethylmethacrylate, partially quaternized with diethyl sulfate....Industry specifications for Polyquaternium-11 allow residual vinylpyrrolidone to a maximum concentration of 1.0%. ...The principal use of Polyquaternium-11 in cosmetic products is in hair care preparations., Polyvinylpyrrolidone, Vinyl Acetate Copolymer (PVP, VA Copolymer) is the copolymer of vinyl pyrrolidone (VP) and vinyl acetate (VA) monomers. The copolymers vary in their ratio of VP to VA and range from 70:30 to 30:70 VP to VA., U.S. Production: 2023: 55, 000, 000 - <70, 000 lb, 2022: 55, 2021: 55, 2020: 55, General Manufacturing Information: Printing Ink Manufacturing, All Other Basic Organic Chemical Manufacturing, Adhesive Manufacturing, All Other Chemical Product and Preparation Manufacturing, 2-Pyrrolidinone, 1-ethenyl-: ACTIVE, PVP, VA Copolymer is used in tablet coating, spray bandages, protective masks, spray or rub-on gloves, plant leaf sprays, shoe polishes, and film production, it is also used as a dye medium in adhesive sticks and in the synthesis of peptides..

Technical Profile

What this product is

N-Vinyl-2-pyrrolidone is a chemical compound with CAS registry number 88-12-0 and molecular formula C6H9NO (molecular weight 111.07 g/mol).

Identification

CAS number: 88-12-0

Its molecular formula C6H9NO comprises 6 C, 9 H, 1 N, 1 O atoms.

Also known as: N-Vinyl-2-pyrrolidone · N-乙烯基吡咯烷酮 · PVP

Frequently Asked Questions

What is the CAS number of N-Vinyl-2-pyrrolidone?

The CAS registry number of N-Vinyl-2-pyrrolidone is 88-12-0.

What is the molecular formula and molecular weight of N-Vinyl-2-pyrrolidone?

Molecular formula C6H9NO, molecular weight 111.07 g/mol.

What other names is N-Vinyl-2-pyrrolidone known by?

It is also registered under: N-Vinyl-2-pyrrolidone, N-乙烯基吡咯烷酮, PVP.

What are the documented applications of N-Vinyl-2-pyrrolidone?

Recorded applications: Uses: Used as a monomer in the production of polyvinyl pyrrolidone, also used in the production of other polymers and organic chemicals, [ACGIH], Using Disinfectants or Biocides [Category: Clean], Plastic Composites Manufacturing [Category: Industry], Used to manufacture water-soluble and insoluble forms of polyvinyl pyrrolidone for pharmaceutical and cosmetic industries and to make copolymers with other monomers intended for use in contact with food. ...Used in cast films adherent to glass, metals, plastics., Solvent for resins, co-monomer for polymerization, binder in cosmetic and pharmaceutical preparations., ...About 10-15% of the monomer is used in the pharmaceutical industry for the production of PVP-iodine complex used as a disinfectant. It is also used as a reactive solvent of UV-curable resins for the production of printing inks and paints as paper and textile auxiliaries, and as an additive in the cosmetics industry., ... Precursor and intermediate for process auxiliaries and additives. The main areas of use are the production of polyvinylpyrrolidone and copolymers, the preferred comonomers being vinyl acetate and methyl acrylate., For more Uses (Complete) data for 2-PYRROLIDINONE, 1-ETHENYL- (6 total), please visit the HSDB record page., Use Classification: Cosmetics -> Film forming, Binding, Antistatic, Emulsion stabilizing, Hair fixing, Industry Uses: Monomers, Adhesion, cohesion promoter, Intermediate, Not Known or Reasonably Ascertainable, Consumer Uses: Adhesion, Household Products: Information on 179 consumer products that contain Polyvinylpyrrolidone (PVP) in the following categories is provided:, • Commercial, Institutional, • Inside the Home, • Personal Care, • Pet Care, Methods of Manufacturing: Industrially, NVP is produced by reacting 2-pyrrolidone with acetylene in high-pressure autoclaves at 130-160 °C and pressures of up to 2.6 MPa. Vinylation proceeds in the liquid phase and is catalyzed by 2-pyrrolidone-potassium, which is obtained by dissolving 1-5% potassium hydroxide (the water formed is removed by distillation in vacuo) or potassium in 2-pyrrolidone. To avoid the danger of explosions acetylene-nitrogen mixtures are used instead of acetylene. The crude product obtained by continuous or batch production is purified by vacuum distillation., Formulations, Preparations: A typical commercial product has the following composition: NVP content, minimum 99 weight percent, 2-pyrrolidone, maximum 0.2 weight percent, water, maximum 0.1 weight percent, color index (freshly filled, APHA), 40 maximum, stabilizers: 10 ppm N, N'-bis(1-methylpropyl)-1, 4-benzenediamine or 0.1 weight percent sodium hydroxide., Polyquaternium-11 is a copolymer of vinylpyrrolidone and dimethylamine ethylmethacrylate, partially quaternized with diethyl sulfate....Industry specifications for Polyquaternium-11 allow residual vinylpyrrolidone to a maximum concentration of 1.0%. ...The principal use of Polyquaternium-11 in cosmetic products is in hair care preparations., Polyvinylpyrrolidone, Vinyl Acetate Copolymer (PVP, VA Copolymer) is the copolymer of vinyl pyrrolidone (VP) and vinyl acetate (VA) monomers. The copolymers vary in their ratio of VP to VA and range from 70:30 to 30:70 VP to VA., U.S. Production: 2023: 55, 000, 000 - <70, 000 lb, 2022: 55, 2021: 55, 2020: 55, General Manufacturing Information: Printing Ink Manufacturing, All Other Basic Organic Chemical Manufacturing, Adhesive Manufacturing, All Other Chemical Product and Preparation Manufacturing, 2-Pyrrolidinone, 1-ethenyl-: ACTIVE, PVP, VA Copolymer is used in tablet coating, spray bandages, protective masks, spray or rub-on gloves, plant leaf sprays, shoe polishes, and film production, it is also used as a dye medium in adhesive sticks and in the synthesis of peptides..

PubChem Public Data

Independent reference data for N-Vinyl-2-pyrrolidone (CAS 88-12-0), compiled from public chemistry databases.

Registry identifiers across databases

CAS 号88-12-0
PubChem CID6917
分子式C6H9NO
分子量111.07 g/mol
IUPAC 名称1-ethenylpyrrolidin-2-one
InChIKeyWHNWPMSKXPGLAX-UHFFFAOYSA-N
UNII(FDA)76H9G81541
ChEBI 编号CHEBI:82551

Computed descriptors

Molecular Weight111.14
XLogP30.4
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Exact Mass111.068413911
Monoisotopic Mass111.068413911
Topological Polar Surface Area20.3
Heavy Atom Count8

Physicochemical values on record

Boiling Point96 °C @ 14 mm Hg; 193 °C @ 400 mm Hg
Boiling Pointat 1.3kPa: 90-93 °C
Boiling Point194 °F
Melting Point13 °C
Melting Point57 °F
Flash Point95 °C
Flash Point100.5 °C (213 °F) open cup
Flash Point95 °C closed cup
Flash Point93 °C
Flash Point199.4 °F

Synonyms and trade names

88-12-0; N-VINYL-2-PYRROLIDONE; 1-Vinyl-2-pyrrolidone; 1-Vinyl-2-pyrrolidinone; Vinylpyrrolidone; 1-ethenylpyrrolidin-2-one; 2-Pyrrolidinone, 1-ethenyl-; Vinylbutyrolactam; Vinylpyrrolidinone; 1-Vinylpyrrolidinone; 1-Ethenyl-2-pyrrolidinone; DTXSID2021440; DTXCID101440; RefChem:1092137; 201-800-4; 1-vinylpyrrolidin-2-one

Regulatory listings held on file

法规与食品接触FDA Substance added to food: PROCESSING AID, SURFACE-FINISHING AGENT
FDA 21 CFR 中列出的食品接触物质清单:FCS
POLYVINYL POLYPYRROLIDONE
CIR / INCI: Antistatic; Film forming; Binding; Emulsion stabilizing; Hair fixing
GHS 通报统计0.1% (1 / 963)

GHS hazard classification

GHS 通报统计0.1% (1 / 963)
已通报的危害声明H302, H312, H318, H332, H335, H351, H373, H311

What the public record says

N-乙烯基吡咯烷酮 的 CAS 号为 88-12-0,分子式 C6H9NO,分子量 111.07 g/mol。 UNII 76H9G81541; ChEBI 82551; InChIKey WHNWPMSKXPGLAX-UHFFFAOYSA-N. Boiling Point: 96 °C @ 14 mm Hg; 193 °C @ 400 mm Hg; Boiling Point: at 1.3kPa: 90-93 °C; Boiling Point: 194 °F.

Source: PubChem / Wikidata; the batch COA governs where values differ.

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