马斯科内（CAS 22460-48-6）：分子式 C16H30O、分子量 238.41。
| CAS号 | 22460-48-6 |
|---|---|
| 分子式 | C16H30O |
| 分子量 | 238.41 |
| 熔点 | 8.60 °C. @ 760.00 mm Hg |
| 沸点 | 329 °C; 130 °C @ 0.5 mm Hg |
| LogP | 6.2 |
| 应用领域 | Uses: Fragrant component of musk、[Merck Index] Used in perfumes and as a flavor ingredient、[HSDB]、FLAVOR INGREDIENT、DL-FORM、Used in perfumes over a wide range of concns、Aroma chemicals、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Consumer Uses: Fragrance、Methods of Manufacturing: INFUSIONS & TINCTURES...PREPD BY ALCOHOLIC EXTRACTION OF MUSK GRAINS. BY CONCENTRATING ALCOHOLIC EXTRACTS...POSSIBLE TO PREPARE A "MUSK RESINOID." TRUE RESINOID IS PREPD BY PETROLEUM ETHER EXTRACTION OF MUSK GRAINS. MUSK ABSOLUTE IS PREPARED BY ALCOHOLIC EXTRACTION FROM RESINOID.、MUSK、Synthesis of the +、- form: Ziegler、Weber、Ann 512、164 (1934)、Ruzicka、Stoll、Helv Chim Acta 17、1308 (1934)、Hunsdiecker、Ber 75B、1197 (1942). Recent syntheses: Stork、McDonald、J Am Chem Soc 97、1264 (1975): H.G. Fliri et al、Monatch Chem 110、245 (1979)、C. Fehr et al.、Helv Chim Acta 62、2655 (1979)、K. H. Schulte-Elte et al.、ibid 2673、G. Cantoni et al.、J Org Chem 45、1906 (1980).、(Natural) Secretion from preputial follicles of the musk deer. (Synthetic) (1) Ketones and lactones with 15- or 16-carbon rings、structurally resembling the odiferous principles of matural musk、civet、and musky-type plants. Among these are ambrettolide、civetone、muscone、exatolide. (2) Nitrated compounds、usually nitrated tert-butyl-toluenes or xylenes or related compounds.、FROM THE CONDENSATION OF DODECAMETHYLENE-ALPHA、OMEGA-DIMETHYLKETONE HEXADECANE... NATURAL OCCURRENCE: IN NATURAL MUSK. REGULATORY STATUS: FEMA NUMBER 3434.、Formulations、Preparations: THE DRIED、UNOPENED POUCHES OF COMMERCE ARE DISTINGUISHED BY THE FOLLOWING NAMES: TONQUIN、BLUE SKIN、YUNNANN、SAWKO、CABARDIN、NEPAL、& ASSAM. GOOD QUALITY POUCHES CONTAIN APPROX 70% MUSK、WHILE LESS VALUABLE ONES CONTAIN AS LITTLE AS 40% MUSK.、U.S. Production: 2020: 49 lb、General Manufacturing Information: Cyclopentadecanone、3-methyl-: ACTIVE、MUSK CONSISTS、...OF A GLANDULAR SECRETION OF THE、ADULT、MALE MUSK DEER OF TIBET、SOUTHERN CHINA、NORTHERN INDIA、& THROUGHOUT THE HIMALAYAN HIGHLANDS. SECRETION...IS A REDDISH-BROWN、PASTE-LIKE MASS WITH A VERY STRONG、PENETRATING ODOR.、Natural musks are macrocyclic ketones or lactones having approx 15 carbons in their ring structures. Synthetic musks are of greater industrial importance and incl nitro and non-nitro benzenes、indans、and tetralins、derivatives of hydrindacene、isochroman、naphthindan、and coumarin.、Musks、The three most commonly used in perfumery are musk ambrette、musk ketone、and musk xylene.、Synthetic musk、... Due to the many steps involved and poor yields、syntheses、are not widely used on an industrial scale.、For more General Manufacturing Information (Complete) data for MUSKONE (7 total)、please visit the HSDB record page. |
登记用途：Uses: Fragrant component of musk、[Merck Index] Used in perfumes and as a flavor ingredient、[HSDB]、FLAVOR INGREDIENT、DL-FORM、Used in perfumes over a wide range of concns、Aroma chemicals、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Consumer Uses: Fragrance、Methods of Manufacturing: INFUSIONS & TINCTURES...PREPD BY ALCOHOLIC EXTRACTION OF MUSK GRAINS. BY CONCENTRATING ALCOHOLIC EXTRACTS...POSSIBLE TO PREPARE A "MUSK RESINOID." TRUE RESINOID IS PREPD BY PETROLEUM ETHER EXTRACTION OF MUSK GRAINS. MUSK ABSOLUTE IS PREPARED BY ALCOHOLIC EXTRACTION FROM RESINOID.、MUSK、Synthesis of the +、- form: Ziegler、Weber、Ann 512、164 (1934)、Ruzicka、Stoll、Helv Chim Acta 17、1308 (1934)、Hunsdiecker、Ber 75B、1197 (1942). Recent syntheses: Stork、McDonald、J Am Chem Soc 97、1264 (1975): H.G. Fliri et al、Monatch Chem 110、245 (1979)、C. Fehr et al.、Helv Chim Acta 62、2655 (1979)、K. H. Schulte-Elte et al.、ibid 2673、G. Cantoni et al.、J Org Chem 45、1906 (1980).、(Natural) Secretion from preputial follicles of the musk deer. (Synthetic) (1) Ketones and lactones with 15- or 16-carbon rings、structurally resembling the odiferous principles of matural musk、civet、and musky-type plants. Among these are ambrettolide、civetone、muscone、exatolide. (2) Nitrated compounds、usually nitrated tert-butyl-toluenes or xylenes or related compounds.、FROM THE CONDENSATION OF DODECAMETHYLENE-ALPHA、OMEGA-DIMETHYLKETONE HEXADECANE... NATURAL OCCURRENCE: IN NATURAL MUSK. REGULATORY STATUS: FEMA NUMBER 3434.、Formulations、Preparations: THE DRIED、UNOPENED POUCHES OF COMMERCE ARE DISTINGUISHED BY THE FOLLOWING NAMES: TONQUIN、BLUE SKIN、YUNNANN、SAWKO、CABARDIN、NEPAL、& ASSAM. GOOD QUALITY POUCHES CONTAIN APPROX 70% MUSK、WHILE LESS VALUABLE ONES CONTAIN AS LITTLE AS 40% MUSK.、U.S. Production: 2020: 49 lb、General Manufacturing Information: Cyclopentadecanone、3-methyl-: ACTIVE、MUSK CONSISTS、...OF A GLANDULAR SECRETION OF THE、ADULT、MALE MUSK DEER OF TIBET、SOUTHERN CHINA、NORTHERN INDIA、& THROUGHOUT THE HIMALAYAN HIGHLANDS. SECRETION...IS A REDDISH-BROWN、PASTE-LIKE MASS WITH A VERY STRONG、PENETRATING ODOR.、Natural musks are macrocyclic ketones or lactones having approx 15 carbons in their ring structures. Synthetic musks are of greater industrial importance and incl nitro and non-nitro benzenes、indans、and tetralins、derivatives of hydrindacene、isochroman、naphthindan、and coumarin.、Musks、The three most commonly used in perfumery are musk ambrette、musk ketone、and musk xylene.、Synthetic musk、... Due to the many steps involved and poor yields、syntheses、are not widely used on an industrial scale.、For more General Manufacturing Information (Complete) data for MUSKONE (7 total)、please visit the HSDB record page.。
马斯科内 是一种化工化合物，登记 CAS 号为 22460-48-6，分子式 C16H30O（分子量 238.41）。
登记 CAS 号：22460-48-6
其分子式 C16H30O 由 16 个碳、30 个氢、1 个氧 组成。
别名/同义词：马斯科内 · Muskone
马斯科内 的 CAS 登记号为 22460-48-6。
分子式 C16H30O，分子量 238.41。
别名/同义词：马斯科内、Muskone。
登记用途：Uses: Fragrant component of musk、[Merck Index] Used in perfumes and as a flavor ingredient、[HSDB]、FLAVOR INGREDIENT、DL-FORM、Used in perfumes over a wide range of concns、Aroma chemicals、Use Classification: Fragrance Ingredients、Flavouring Agent -> FLAVOURING_AGENT -> JECFA Functional Classes、Flavoring Agents -> JECFA Flavorings Index、Consumer Uses: Fragrance、Methods of Manufacturing: INFUSIONS & TINCTURES...PREPD BY ALCOHOLIC EXTRACTION OF MUSK GRAINS. BY CONCENTRATING ALCOHOLIC EXTRACTS...POSSIBLE TO PREPARE A "MUSK RESINOID." TRUE RESINOID IS PREPD BY PETROLEUM ETHER EXTRACTION OF MUSK GRAINS. MUSK ABSOLUTE IS PREPARED BY ALCOHOLIC EXTRACTION FROM RESINOID.、MUSK、Synthesis of the +、- form: Ziegler、Weber、Ann 512、164 (1934)、Ruzicka、Stoll、Helv Chim Acta 17、1308 (1934)、Hunsdiecker、Ber 75B、1197 (1942). Recent syntheses: Stork、McDonald、J Am Chem Soc 97、1264 (1975): H.G. Fliri et al、Monatch Chem 110、245 (1979)、C. Fehr et al.、Helv Chim Acta 62、2655 (1979)、K. H. Schulte-Elte et al.、ibid 2673、G. Cantoni et al.、J Org Chem 45、1906 (1980).、(Natural) Secretion from preputial follicles of the musk deer. (Synthetic) (1) Ketones and lactones with 15- or 16-carbon rings、structurally resembling the odiferous principles of matural musk、civet、and musky-type plants. Among these are ambrettolide、civetone、muscone、exatolide. (2) Nitrated compounds、usually nitrated tert-butyl-toluenes or xylenes or related compounds.、FROM THE CONDENSATION OF DODECAMETHYLENE-ALPHA、OMEGA-DIMETHYLKETONE HEXADECANE... NATURAL OCCURRENCE: IN NATURAL MUSK. REGULATORY STATUS: FEMA NUMBER 3434.、Formulations、Preparations: THE DRIED、UNOPENED POUCHES OF COMMERCE ARE DISTINGUISHED BY THE FOLLOWING NAMES: TONQUIN、BLUE SKIN、YUNNANN、SAWKO、CABARDIN、NEPAL、& ASSAM. GOOD QUALITY POUCHES CONTAIN APPROX 70% MUSK、WHILE LESS VALUABLE ONES CONTAIN AS LITTLE AS 40% MUSK.、U.S. Production: 2020: 49 lb、General Manufacturing Information: Cyclopentadecanone、3-methyl-: ACTIVE、MUSK CONSISTS、...OF A GLANDULAR SECRETION OF THE、ADULT、MALE MUSK DEER OF TIBET、SOUTHERN CHINA、NORTHERN INDIA、& THROUGHOUT THE HIMALAYAN HIGHLANDS. SECRETION...IS A REDDISH-BROWN、PASTE-LIKE MASS WITH A VERY STRONG、PENETRATING ODOR.、Natural musks are macrocyclic ketones or lactones having approx 15 carbons in their ring structures. Synthetic musks are of greater industrial importance and incl nitro and non-nitro benzenes、indans、and tetralins、derivatives of hydrindacene、isochroman、naphthindan、and coumarin.、Musks、The three most commonly used in perfumery are musk ambrette、musk ketone、and musk xylene.、Synthetic musk、... Due to the many steps involved and poor yields、syntheses、are not widely used on an industrial scale.、For more General Manufacturing Information (Complete) data for MUSKONE (7 total)、please visit the HSDB record page.。
马斯科内（CAS 22460-48-6）的独立参考数据，整理自公开化学数据库。
| CAS 号 | 22460-48-6 |
|---|---|
| PubChem CID | 10947 |
| 分子式 | C16H30O |
| IUPAC 名称 | 3-methylcyclopentadecan-1-one |
| UNII（FDA） | 5JO79R7S9R |
| FEMA 编号 | 3434 |
| JECFA 编号 | 1402 |
| Molecular Weight | 238.41 |
|---|---|
| XLogP3 | 6.2 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 238.229665576 |
| Monoisotopic Mass | 238.229665576 |
| Topological Polar Surface Area | 17.1 |
| Heavy Atom Count | 17 |
| Boiling Point | 329 °C; 130 °C @ 0.5 mm Hg |
|---|---|
| Boiling Point | 320.00 to 329.00 °C. @ 760.00 mm Hg |
| Melting Point | 8.60 °C. @ 760.00 mm Hg |
| Density | 0.9921 g/cu cm @ 17 °C |
3-Methylcyclopentadecanone; 541-91-3; 3-Methylcyclopentadecan-1-one; MUSKONE; Cyclopentadecanone, 3-methyl-; Methylexaltone; Moschus ketone; dl-muscone; 3-Methyl-1-cyclopentadecanone; 5-Methyl-1-cyclopentadecanone; FEMA No. 3434; dextro,laevo-muscone; HSDB 1219; EINECS 208-795-8; 5JO79R7S9R; AI3-38746
| 法规与食品接触 | FDA Substance added to food: FLAVORING AGENT OR ADJUVANT FLAVOURING_AGENT: Flavouring Agent Flavoring Agents Floral No safety concern at current levels of intake when used as a flavouring agent TRS 928-JECFA 63/86 |
|---|---|
| GHS 通报统计 | 99.7% (1559 / 1564) |
| GHS 通报统计 | 99.7% (1559 / 1564) |
|---|
马斯科内 · CAS 22460-48-6 · C16H30O. UNII 5JO79R7S9R. Boiling Point: 329 °C; 130 °C @ 0.5 mm Hg; Boiling Point: 320.00 to 329.00 °C. @ 760.00 mm Hg; Melting Point: 8.60 °C. @ 760.00 mm Hg.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Muskone