孟鲁司特（CAS 1124196-02-6）：分子式 C35H36ClNO3S、分子量 586.2。
| CAS号 | 1124196-02-6 |
|---|---|
| 分子式 | C35H36ClNO3S |
| 分子量 | 586.2 |
| 熔点 | 275.9 |
| LogP | 7.9 |
| 应用领域 | Uses: MEDICATION、Therapeutic Category: Antiasthmatic、Use (kg、approx.) in Germany (2009): >250、Use (kg) in USA (2002): 2720、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Consumption (g per capita) in the USA (2002): 0.00964、Calculated removal (%): 94、Use Classification: Pharmaceuticals、Methods of Manufacturing: Preparation: ML Belley et al、EP 480717、eidem、US 5565473 (1992、1996 both to Merck Frosst)、Formulations、Preparations: Montelukast oral formulations: Granules 4 mg (of Montelukast) Singulair、Merck、Tablets、chewable 4 and 5 mg (of Montelukast) Singulair、film-coated 10 mg (of Montelukast) Singulair、General Manufacturing Information: Montelukast sodium、the active ingredient in Singulair、is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotrience CysLT、receptor.、Montelukast sodium |
登记用途：Uses: MEDICATION、Therapeutic Category: Antiasthmatic、Use (kg、approx.) in Germany (2009): >250、Use (kg) in USA (2002): 2720、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Consumption (g per capita) in the USA (2002): 0.00964、Calculated removal (%): 94、Use Classification: Pharmaceuticals、Methods of Manufacturing: Preparation: ML Belley et al、EP 480717、eidem、US 5565473 (1992、1996 both to Merck Frosst)、Formulations、Preparations: Montelukast oral formulations: Granules 4 mg (of Montelukast) Singulair、Merck、Tablets、chewable 4 and 5 mg (of Montelukast) Singulair、film-coated 10 mg (of Montelukast) Singulair、General Manufacturing Information: Montelukast sodium、the active ingredient in Singulair、is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotrience CysLT、receptor.、Montelukast sodium。
孟鲁司特 是一种化工化合物，登记 CAS 号为 1124196-02-6，分子式 C35H36ClNO3S（分子量 586.2）。
登记 CAS 号：1124196-02-6
其分子式 C35H36ClNO3S 由 35 个碳、36 个氢、1 个氯、1 个氮、3 个氧、1 个硫 组成。
别名/同义词：孟鲁司特 · Montelukast
孟鲁司特 的 CAS 登记号为 1124196-02-6。
分子式 C35H36ClNO3S，分子量 586.2。
别名/同义词：孟鲁司特、Montelukast。
登记用途：Uses: MEDICATION、Therapeutic Category: Antiasthmatic、Use (kg、approx.) in Germany (2009): >250、Use (kg) in USA (2002): 2720、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Consumption (g per capita) in the USA (2002): 0.00964、Calculated removal (%): 94、Use Classification: Pharmaceuticals、Methods of Manufacturing: Preparation: ML Belley et al、EP 480717、eidem、US 5565473 (1992、1996 both to Merck Frosst)、Formulations、Preparations: Montelukast oral formulations: Granules 4 mg (of Montelukast) Singulair、Merck、Tablets、chewable 4 and 5 mg (of Montelukast) Singulair、film-coated 10 mg (of Montelukast) Singulair、General Manufacturing Information: Montelukast sodium、the active ingredient in Singulair、is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotrience CysLT、receptor.、Montelukast sodium。
孟鲁司特（CAS 1124196-02-6）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 1124196-02-6 |
|---|---|
| PubChem CID | 5281040 |
| Molecular formula | C35H36ClNO3S |
| IUPAC name | 2-[1-[[(1R)-1-[3-[(E)-2-(7-chloroquinolin-2-yl)ethenyl]phenyl]-3-[2-(2-hydroxypropan-2-yl)phenyl]propyl]sulfanylmethyl]cyclopropyl]acetic acid |
| UNII (FDA) | MHM278SD3E |
| Molecular Weight | 586.2 |
|---|---|
| XLogP3 | 7.7 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 12 |
| Exact Mass | 585.2104429 |
| Monoisotopic Mass | 585.2104429 |
| Topological Polar Surface Area | 95.7 |
| Heavy Atom Count | 41 |
| Melting Point | 275.9 |
|---|---|
| Solubility | 8.20e-06 g/L |
| LogP | 7.9 |
montelukast; 158966-92-8; Brondilat; MHM278SD3E; DTXSID9023334; CHEBI:50730; Montelukastum; RefChem:6040; DTXCID403334; R03DC03; MK-0476; Singulair; 142522-28-9; MFCD05662278; cis-Montelukast; Montelukast (INN)
| GHS notification summary | 50% (1 / 2) |
|---|
| GHS notification summary | 50% (1 / 2) |
|---|---|
| Reported hazard statements | H302 (50%), H312 (50%), H332 (50%) |
This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.
H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]
Montelukast · CAS 1124196-02-6 · C35H36ClNO3S. UNII MHM278SD3E. Melting Point: 275.9; Solubility: 8.20e-06 g/L; LogP: 7.9.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Montelukast