盐酸米托蒽醌（CAS 70476-82-3）：分子式 C22H30Cl2N4O6、分子量 517.4。
| CAS号 | 70476-82-3 |
|---|---|
| 分子式 | C22H30Cl2N4O6 |
| 分子量 | 517.4 |
| 熔点 | 203-5 °C |
| 应用领域 | Uses: Used as an antineoplastic drug、[Merck Index]、DNA binding or cleaving agent used to treat acute nonlymphocytic leukemia、including myclogenous、promyclocytic、monocytic、and erythroid acute leukemias、Mitoxantrone's、range of antitumor activity is confined to leukemias、breast cancer、and prostate cancer. ... It also is used as a component of experimental high-dose chemotherapy regimens、with uncertain efficacy.、Use (kg) in USA (2002): 1、Consumption (g per capita) in the USA (2002): 2.34e-06、Calculated removal (%): 23.7 |
登记用途：Uses: Used as an antineoplastic drug、[Merck Index]、DNA binding or cleaving agent used to treat acute nonlymphocytic leukemia、including myclogenous、promyclocytic、monocytic、and erythroid acute leukemias、Mitoxantrone's、range of antitumor activity is confined to leukemias、breast cancer、and prostate cancer. ... It also is used as a component of experimental high-dose chemotherapy regimens、with uncertain efficacy.、Use (kg) in USA (2002): 1、Consumption (g per capita) in the USA (2002): 2.34e-06、Calculated removal (%): 23.7。
盐酸米托蒽醌 是一种化工化合物，登记 CAS 号为 70476-82-3，分子式 C22H30Cl2N4O6（分子量 517.4）。
登记 CAS 号：70476-82-3
其分子式 C22H30Cl2N4O6 由 22 个碳、30 个氢、2 个氯、4 个氮、6 个氧 组成。
别名/同义词：盐酸米托蒽醌 · Mitoxantrone hydrochloride
盐酸米托蒽醌 的 CAS 登记号为 70476-82-3。
分子式 C22H30Cl2N4O6，分子量 517.4。
别名/同义词：盐酸米托蒽醌、Mitoxantrone hydrochloride。
登记用途：Uses: Used as an antineoplastic drug、[Merck Index]、DNA binding or cleaving agent used to treat acute nonlymphocytic leukemia、including myclogenous、promyclocytic、monocytic、and erythroid acute leukemias、Mitoxantrone's、range of antitumor activity is confined to leukemias、breast cancer、and prostate cancer. ... It also is used as a component of experimental high-dose chemotherapy regimens、with uncertain efficacy.、Use (kg) in USA (2002): 1、Consumption (g per capita) in the USA (2002): 2.34e-06、Calculated removal (%): 23.7。
盐酸米托蒽醌（CAS 70476-82-3）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 70476-82-3 |
|---|---|
| PubChem CID | 51082 |
| Molecular formula | C22H30Cl2N4O6 |
| IUPAC name | 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;dihydrochloride |
| UNII (FDA) | U6USW86RD0 |
| Molecular Weight | 517.4 |
|---|---|
| Hydrogen Bond Donor Count | 10 |
| Hydrogen Bond Acceptor Count | 10 |
| Rotatable Bond Count | 12 |
| Exact Mass | 516.1542401 |
| Monoisotopic Mass | 516.1542401 |
| Topological Polar Surface Area | 163 |
| Heavy Atom Count | 34 |
| Melting Point | 203-5 °C |
|---|---|
| Solubility | H2O 5- 10 (mg/mL) |
| Solubility | 0.1NHCl 1 - 3 (mg/mL) |
| Solubility | 10% Ethanol 3 - 5 (mg/mL) |
| Solubility | 95% Ethanol < 1 (mg/mL) |
| Solubility | Methanol < 1 (mg/mL) |
70476-82-3; Mitoxantrone hydrochloride; Mitoxantrone dihydrochloride; CL-232315; Onkotrone; DTXSID0045173; Mitozantrone hydrochloride; CL 232,315; U6USW86RD0; NSC-301739; CL 232315; DTXCID8025173; CHEBI:50727; 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthraquinone dihydrochloride; 9,10-Anthracenedione, 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)-, dihydrochloride; 1,4-Dihydroxy-5,8-bis[[2-[(2-hydroxyethyl)amino]ethyl]amino]anthraquinone dihydrochloride
| Reported hazard statements | H340 (92.9%), H360 (92.9%), H302, H310, H341, H351, H370, H372 |
|---|
H340 (92.9%): May cause genetic defects [Danger Germ cell mutagenicity]
H360 (92.9%): May damage fertility or the unborn child [Danger Reproductive toxicity]
Mitoxantrone hydrochloride · CAS 70476-82-3 · C22H30Cl2N4O6. UNII U6USW86RD0. Melting Point: 203-5 °C; Solubility: H2O 5- 10 (mg/mL); Solubility: 0.1NHCl 1 - 3 (mg/mL).
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Mitoxantrone hydrochloride