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米拉贝隆

CAS 223673-61-8C21H24N4O2SMW 396.5

米拉贝隆(CAS 223673-61-8):分子式 C21H24N4O2S、分子量 396.5。

产品概览

CAS号223673-61-8
分子式C21H24N4O2S
分子量396.5
LogP2.1

技术档案

这个产品是什么

米拉贝隆 是一种化工化合物,登记 CAS 号为 223673-61-8,分子式 C21H24N4O2S(分子量 396.5)。

识别信息

登记 CAS 号:223673-61-8

其分子式 C21H24N4O2S 由 21 个碳、24 个氢、4 个氮、2 个氧、1 个硫 组成。

别名/同义词:米拉贝隆 · Mirabegron

常见问题

米拉贝隆 的 CAS 号是多少?

米拉贝隆 的 CAS 登记号为 223673-61-8。

米拉贝隆 的分子式与分子量是多少?

分子式 C21H24N4O2S,分子量 396.5。

米拉贝隆 还有哪些别名?

别名/同义词:米拉贝隆、Mirabegron。

PubChem 公开数据

米拉贝隆(CAS 223673-61-8)的独立参考数据,整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number223673-61-8
PubChem CID9865528
Molecular formulaC21H24N4O2S
IUPAC name2-(2-amino-1,3-thiazol-4-yl)-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]acetamide
UNII (FDA)MVR3JL3B2V
Pharmacopoeial monographEuropean Pharmacopoeia monograph

计算分子描述符

Molecular Weight396.5
XLogP32.1
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count6
Rotatable Bond Count9
Exact Mass396.16199719
Monoisotopic Mass396.16199719
Topological Polar Surface Area129
Heavy Atom Count28

在册的理化数值

Solubility0.082

在册的记载用途

    Mirabegron is indicated for the treatment of overactive bladder (OAB) - with symptoms of urge urinary incontinence, urgency, and urinary frequency - either alone or in combination with [solifenacin]. It is also indicated for the treatment of neurogenic detrusor overactivity (NDO) in pediatric patients 3 years of age and older and weighing 35kg or more.Mirabegron is a beta-3 adrenergic agonist that is used for treatment of overactive bladder syndrome. Mirabegron has not been implicated in causing liver enzyme elevations or clinically apparent acute liver injury.

    同义词与商品名

    Mirabegron; 223673-61-8; Myrbetriq; Betanis; Betmiga; YM-178; YM178; MVR3JL3B2V; 2-(2-amino-1,3-thiazol-4-yl)-N-[4-(2-{[(2R)-2-hydroxy-2-phenylethyl]amino}ethyl)phenyl]acetamide; CHEBI:65349; DTXSID101021648; 2-(2-amino-1,3-thiazol-4-yl)-N-[4-[2-[[(2R)-2-hydroxy-2-phenylethyl]amino]ethyl]phenyl]acetamide; 2-(2-Aminothiazol-4-yl)-4'-(2-((2-hydroxy-2-phenylethyl)amino)ethyl)acetanilide; 4-Thiazoleacetamide, 2-amino-N-(4-(2-(((2R)-2-hydroxy-2-phenylethyl)amino)ethyl)phenyl)-; 2-(2-AMINO-1,3-THIAZOL-4-YL)-N-(4-(2-(((2R)-2-HYDROXY-2-PHENYLETHYL)AMINO)ETHYL)PHENYL)ACETAMIDE; mirabegronum

    GHS 危害分类

    Reported hazard statementsH302 (72.7%), H317 (54.5%), H319 (27.3%), H361 (45.5%), H373 (45.5%), H410 (36.4%)

    H302 (72.7%): Harmful if swallowed [Warning Acute toxicity, oral]

    H317 (54.5%): May cause an allergic skin reaction [Warning Sensitization, Skin]

    公开数据库对它的描述

    Mirabegron · CAS 223673-61-8 · C21H24N4O2S. UNII MVR3JL3B2V. European Pharmacopoeia monograph. Solubility: 0.082.

    数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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