异丙甲草胺（CAS 63150-68-5）：分子式 C15H22ClNO2、分子量 283.79。
| CAS号 | 63150-68-5 |
|---|---|
| 分子式 | C15H22ClNO2 |
| 分子量 | 283.79 |
| 熔点 | -62.1 °C |
| 沸点 | 212 °F at 0.001 mmHg (USCG, 1999) |
| LogP | log Kow = 3.13 |
| 应用领域 | Uses: Used to control weeds in crops of corn、soybeans、peanuts、sorghum、potatoes、peas、cotton、safflower、stone fruits、nut trees、and ornamentals、also used on roadways、[EXTOXNET] Used in corn、and soybeans、[Krieger、p. 1762]、Farming (Pesticides) [Category: Industry]、For metolachlor (USEPA、OPP Pesticide Code: 108801) ACTIVE products with label matches.、SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、Herbicide、Preemergence and preplant incorporated weed control、Control of annual grasses and some broad-leaved weeds ... Often used in combination with broad-leaved herbicides、to extend the spectrum of activity.、S-metolachlor is a chloroactanilide herbicide、classified as a seedling shoot growth inhibitor.、S-Metolachlor、Metolachlor is used for grass and broadleaf weed control in corn、soybean、and cotton. It is also used in combination with other herbicides. It been detected in ground and surface waters and concentrations ranging from 0.08 to 4.5 parts per billion (ppb) throughout the U.S. Evidence of the bioaccumulation of metolachlor in edible species of fish as well as its adverse effect on the growth and development raise concerns on its effects on human health. (L913).、Use Classification: Herbicides、Pesticides -> Herbicides -> Amide herbicides -> Anilide herbicides -> Chloroacetanilide herbicides、HERBICIDES、Methods of Manufacturing: (A) A mixture of 540 g (4.0 mols) of 2-ethyl-6-methylaniline and 306 g (2.0 moles) of 2-bromo-1-methoxypropane is heated for 40 hours at reduced pressure (10 mmHg) to 120 °C with stirring. After it has cooled、the light red、viscous solution is diluted with 200 mL of water and made alkaline with 210 mL of concentrated sodium hydroxide solution. The precipitated product is taken up in ether、and the ethereal solution is washed neutral with water、dried、and evaporated. Distillation of the residue yields pure-2-ethyl-6-methyl-N-[1'-methoxy-prop-2'-yl]-aniline which boils at 64 deg to 66 °C、0.07 Torr. (B) A solution of 9.7 g (0.047 mol) of the intermediate described under (A) and 5.05 g (0.05 mol) of triethylamine in 30 mL of benzene is treated dropwise with a solution of 5.65 g (0.05 mol) of chloroacetyl chloride in 10 mL of absolute benzene、and the mixture is further stirred for 2 hours at room temperature. The reaction mixture is diluted with ether、the solution repeatedly washed with water、and dried. The solvent mixture is evaporated off in vacuo to give pure-2-ethyl-6-methyl-N-[1'-methoxy-prop-2'-yl]-chloroacetanilide.、Preparation: C. Vogel、R. Aebi、DE 2328340、eidem、US 3937730 (1973、1976 both to Ciba-Geigy).、Formulations、Preparations: USEPA、OPP Pesticide Code 108801、Trade Names: Milocep、Dual、CGA-24705、Bicep、codal、Cotoran multi、Primagram、Primextra、Pennant、and Ontrack 8E.、Premix Partners: Atrazine、Chloridazon、Metribuzin.、Formulation types: Emulsifiable concentrate、granule、smoke pellet、suspension concentrate、Technical Metolachlor II (Agan Chem MFG、LTD): Metolachlor 96.8%.、For more Formulations、Preparations (Complete) data for METOLACHLOR (27 total)、please visit the HSDB record page.、Consumption Patterns: (1992) 6X10+7 lbs、General Manufacturing Information: The WHO Recommended Classification of Pesticides by Hazard identifies metolachlor (technical grade) as Class III: slightly hazardous、Main Use: herbicide. |
登记用途：Uses: Used to control weeds in crops of corn、soybeans、peanuts、sorghum、potatoes、peas、cotton、safflower、stone fruits、nut trees、and ornamentals、also used on roadways、[EXTOXNET] Used in corn、and soybeans、[Krieger、p. 1762]、Farming (Pesticides) [Category: Industry]、For metolachlor (USEPA、OPP Pesticide Code: 108801) ACTIVE products with label matches.、SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、Herbicide、Preemergence and preplant incorporated weed control、Control of annual grasses and some broad-leaved weeds ... Often used in combination with broad-leaved herbicides、to extend the spectrum of activity.、S-metolachlor is a chloroactanilide herbicide、classified as a seedling shoot growth inhibitor.、S-Metolachlor、Metolachlor is used for grass and broadleaf weed control in corn、soybean、and cotton. It is also used in combination with other herbicides. It been detected in ground and surface waters and concentrations ranging from 0.08 to 4.5 parts per billion (ppb) throughout the U.S. Evidence of the bioaccumulation of metolachlor in edible species of fish as well as its adverse effect on the growth and development raise concerns on its effects on human health. (L913).、Use Classification: Herbicides、Pesticides -> Herbicides -> Amide herbicides -> Anilide herbicides -> Chloroacetanilide herbicides、HERBICIDES、Methods of Manufacturing: (A) A mixture of 540 g (4.0 mols) of 2-ethyl-6-methylaniline and 306 g (2.0 moles) of 2-bromo-1-methoxypropane is heated for 40 hours at reduced pressure (10 mmHg) to 120 °C with stirring. After it has cooled、the light red、viscous solution is diluted with 200 mL of water and made alkaline with 210 mL of concentrated sodium hydroxide solution. The precipitated product is taken up in ether、and the ethereal solution is washed neutral with water、dried、and evaporated. Distillation of the residue yields pure-2-ethyl-6-methyl-N-[1'-methoxy-prop-2'-yl]-aniline which boils at 64 deg to 66 °C、0.07 Torr. (B) A solution of 9.7 g (0.047 mol) of the intermediate described under (A) and 5.05 g (0.05 mol) of triethylamine in 30 mL of benzene is treated dropwise with a solution of 5.65 g (0.05 mol) of chloroacetyl chloride in 10 mL of absolute benzene、and the mixture is further stirred for 2 hours at room temperature. The reaction mixture is diluted with ether、the solution repeatedly washed with water、and dried. The solvent mixture is evaporated off in vacuo to give pure-2-ethyl-6-methyl-N-[1'-methoxy-prop-2'-yl]-chloroacetanilide.、Preparation: C. Vogel、R. Aebi、DE 2328340、eidem、US 3937730 (1973、1976 both to Ciba-Geigy).、Formulations、Preparations: USEPA、OPP Pesticide Code 108801、Trade Names: Milocep、Dual、CGA-24705、Bicep、codal、Cotoran multi、Primagram、Primextra、Pennant、and Ontrack 8E.、Premix Partners: Atrazine、Chloridazon、Metribuzin.、Formulation types: Emulsifiable concentrate、granule、smoke pellet、suspension concentrate、Technical Metolachlor II (Agan Chem MFG、LTD): Metolachlor 96.8%.、For more Formulations、Preparations (Complete) data for METOLACHLOR (27 total)、please visit the HSDB record page.、Consumption Patterns: (1992) 6X10+7 lbs、General Manufacturing Information: The WHO Recommended Classification of Pesticides by Hazard identifies metolachlor (technical grade) as Class III: slightly hazardous、Main Use: herbicide.。
异丙甲草胺 是一种化工化合物，登记 CAS 号为 63150-68-5，分子式 C15H22ClNO2（分子量 283.79）。
登记 CAS 号：63150-68-5
其分子式 C15H22ClNO2 由 15 个碳、22 个氢、1 个氯、1 个氮、2 个氧 组成。
别名/同义词：异丙甲草胺 · Metolachlor
异丙甲草胺 的 CAS 登记号为 63150-68-5。
分子式 C15H22ClNO2，分子量 283.79。
别名/同义词：异丙甲草胺、Metolachlor。
登记用途：Uses: Used to control weeds in crops of corn、soybeans、peanuts、sorghum、potatoes、peas、cotton、safflower、stone fruits、nut trees、and ornamentals、also used on roadways、[EXTOXNET] Used in corn、and soybeans、[Krieger、p. 1762]、Farming (Pesticides) [Category: Industry]、For metolachlor (USEPA、OPP Pesticide Code: 108801) ACTIVE products with label matches.、SRP: Registered for use in the U.S. but approved pesticide uses may change periodically and so federal、state and local authorities must be consulted for currently approved uses.、Herbicide、Preemergence and preplant incorporated weed control、Control of annual grasses and some broad-leaved weeds ... Often used in combination with broad-leaved herbicides、to extend the spectrum of activity.、S-metolachlor is a chloroactanilide herbicide、classified as a seedling shoot growth inhibitor.、S-Metolachlor、Metolachlor is used for grass and broadleaf weed control in corn、soybean、and cotton. It is also used in combination with other herbicides. It been detected in ground and surface waters and concentrations ranging from 0.08 to 4.5 parts per billion (ppb) throughout the U.S. Evidence of the bioaccumulation of metolachlor in edible species of fish as well as its adverse effect on the growth and development raise concerns on its effects on human health. (L913).、Use Classification: Herbicides、Pesticides -> Herbicides -> Amide herbicides -> Anilide herbicides -> Chloroacetanilide herbicides、HERBICIDES、Methods of Manufacturing: (A) A mixture of 540 g (4.0 mols) of 2-ethyl-6-methylaniline and 306 g (2.0 moles) of 2-bromo-1-methoxypropane is heated for 40 hours at reduced pressure (10 mmHg) to 120 °C with stirring. After it has cooled、the light red、viscous solution is diluted with 200 mL of water and made alkaline with 210 mL of concentrated sodium hydroxide solution. The precipitated product is taken up in ether、and the ethereal solution is washed neutral with water、dried、and evaporated. Distillation of the residue yields pure-2-ethyl-6-methyl-N-[1'-methoxy-prop-2'-yl]-aniline which boils at 64 deg to 66 °C、0.07 Torr. (B) A solution of 9.7 g (0.047 mol) of the intermediate described under (A) and 5.05 g (0.05 mol) of triethylamine in 30 mL of benzene is treated dropwise with a solution of 5.65 g (0.05 mol) of chloroacetyl chloride in 10 mL of absolute benzene、and the mixture is further stirred for 2 hours at room temperature. The reaction mixture is diluted with ether、the solution repeatedly washed with water、and dried. The solvent mixture is evaporated off in vacuo to give pure-2-ethyl-6-methyl-N-[1'-methoxy-prop-2'-yl]-chloroacetanilide.、Preparation: C. Vogel、R. Aebi、DE 2328340、eidem、US 3937730 (1973、1976 both to Ciba-Geigy).、Formulations、Preparations: USEPA、OPP Pesticide Code 108801、Trade Names: Milocep、Dual、CGA-24705、Bicep、codal、Cotoran multi、Primagram、Primextra、Pennant、and Ontrack 8E.、Premix Partners: Atrazine、Chloridazon、Metribuzin.、Formulation types: Emulsifiable concentrate、granule、smoke pellet、suspension concentrate、Technical Metolachlor II (Agan Chem MFG、LTD): Metolachlor 96.8%.、For more Formulations、Preparations (Complete) data for METOLACHLOR (27 total)、please visit the HSDB record page.、Consumption Patterns: (1992) 6X10+7 lbs、General Manufacturing Information: The WHO Recommended Classification of Pesticides by Hazard identifies metolachlor (technical grade) as Class III: slightly hazardous、Main Use: herbicide.。
异丙甲草胺（CAS 63150-68-5）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 63150-68-5 |
|---|---|
| PubChem CID | 4169 |
| Molecular formula | C15H22ClNO2 |
| IUPAC name | 2-chloro-N-(2-ethyl-6-methylphenyl)-N-(1-methoxypropan-2-yl)acetamide |
| UNII (FDA) | X0I01K05X2 |
| Molecular Weight | 283.79 |
|---|---|
| XLogP3 | 3.1 |
| Hydrogen Bond Donor Count | 0 |
| Hydrogen Bond Acceptor Count | 2 |
| Rotatable Bond Count | 6 |
| Exact Mass | 283.1339066 |
| Monoisotopic Mass | 283.1339066 |
| Topological Polar Surface Area | 29.5 |
| Heavy Atom Count | 19 |
| Boiling Point | 212 °F at 0.001 mmHg (USCG, 1999) |
|---|---|
| Boiling Point | BP: 100 °C at 0.001 mm Hg |
| Melting Point | -62.1 °C |
| Flash Point | 190 °C |
| Solubility | In water, 530 mg/L at 20 °C |
| Density | 1.12 g/cu cm at 20 °C |
| Density | 1.12 g/cm³ |
| Vapor Pressure | 0.0000314 [mmHg] |
| Vapor Pressure | 3.14X10-5 mm Hg at 25 °C |
| LogP | log Kow = 3.13 |
metolachlor; 51218-45-2; Pennant; Codal; Dual; Yibingjiacaoan; Dual Magnum; Dual Triple; Metelilachlor; Dual II; Humextra; Ontrack 8E; Dual 720EC; Dual 8E; Dual 960 EC; Metolachlor technical
| GHS notification summary | 4.2% (3 / 71) |
|---|
| GHS notification summary | 4.2% (3 / 71) |
|---|---|
| Reported hazard statements | H317 (94.4%), H330 (53.5%), H400 (42.3%), H410 (42.3%), H370, H303 |
This chemical does not meet GHS hazard criteria for 4.2% (3 of 71) of reports.
H317 (94.4%): May cause an allergic skin reaction [Warning Sensitization, Skin]
Metolachlor · CAS 63150-68-5 · C15H22ClNO2. UNII X0I01K05X2. Boiling Point: 212 °F at 0.001 mmHg (USCG, 1999); Boiling Point: BP: 100 °C at 0.001 mm Hg; Melting Point: -62.1 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Metolachlor