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Methotrexate sodium

CAS 15475-56-6C20H20N8Na2O5MW 498.4

Methotrexate sodium (CAS 15475-56-6) — formula C20H20N8Na2O5, molecular weight 498.4; category inorganic chemicals.

Product Description

Methotrexate sodium (CAS 15475-56-6) is a chemical raw material in the inorganic chemicals category. Its molecular formula C20H20N8Na2O5 comprises 20 C, 20 H, 8 N, 2 Na, 5 O atoms. Its molecular weight is about 498.4. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.

Product Overview

CAS Number15475-56-6
Molecular FormulaC20H20N8Na2O5
Molecular Weight498.4
ApplicationsMethotrexate is indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens and hydatidiform mole. In acute lymphocytic leukemia, methotrexate is indicated in the prophylaxis of meningeal leukemia and is used in maintenance therapy in combination with other chemotherapeutic agents. Methotrexate is also indicated in the treatment of meningeal leukemia. Methotrexate is used alone or in combination with other anticancer agents in the treatment of breast cancer, epidermoid cancers of the head and neck, advanced mycosis fungoides (cutaneous T cell lymphoma), and lung cancer
CategoryInorganic Chemicals

Applications

Documented applications: Methotrexate is indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens and hydatidiform mole. In acute lymphocytic leukemia, methotrexate is indicated in the prophylaxis of meningeal leukemia and is used in maintenance therapy in combination with other chemotherapeutic agents. Methotrexate is also indicated in the treatment of meningeal leukemia. Methotrexate is used alone or in combination with other anticancer agents in the treatment of breast cancer, epidermoid cancers of the head and neck, advanced mycosis fungoides (cutaneous T cell lymphoma), and lung cancer.

Technical Profile

What this product is

Methotrexate sodium is an inorganic compound with CAS registry number 15475-56-6 and molecular formula C20H20N8Na2O5 (molecular weight 498.4), belonging to the inorganic chemicals segment of chemical raw materials.

Identification

CAS number: 15475-56-6

Its molecular formula C20H20N8Na2O5 comprises 20 C, 20 H, 8 N, 2 Na, 5 O atoms.

Also known as: Methotrexate sodium · 甲氨蝶呤钠

Category: inorganic chemicals

Frequently Asked Questions

What is the CAS number of Methotrexate sodium?

The CAS registry number of Methotrexate sodium is 15475-56-6.

What is the molecular formula and molecular weight of Methotrexate sodium?

Molecular formula C20H20N8Na2O5, molecular weight 498.4.

What other names is Methotrexate sodium known by?

It is also registered under: Methotrexate sodium, 甲氨蝶呤钠.

What are the documented applications of Methotrexate sodium?

Recorded applications: Methotrexate is indicated in the treatment of gestational choriocarcinoma, chorioadenoma destruens and hydatidiform mole. In acute lymphocytic leukemia, methotrexate is indicated in the prophylaxis of meningeal leukemia and is used in maintenance therapy in combination with other chemotherapeutic agents. Methotrexate is also indicated in the treatment of meningeal leukemia. Methotrexate is used alone or in combination with other anticancer agents in the treatment of breast cancer, epidermoid cancers of the head and neck, advanced mycosis fungoides (cutaneous T cell lymphoma), and lung cancer.

Which category does Methotrexate sodium belong to?

Category: Inorganic Chemicals.

Packaging & documentation

Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.

PubChem Public Data

Independent reference data for Methotrexate sodium (CAS 15475-56-6), compiled from public chemistry databases.

Registry identifiers across databases

CAS Registry Number15475-56-6
PubChem CID11329481
Molecular formulaC20H20N8Na2O5
IUPAC namedisodium;(2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioate
UNII (FDA)3IG1E710ZN

Computed descriptors

Molecular Weight498.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count12
Rotatable Bond Count7
Exact Mass498.13520433
Monoisotopic Mass498.13520433
Topological Polar Surface Area216
Heavy Atom Count35

Documented uses on record

    Breast Feeding; Lactation; Milk, Human; Abortifacient Agents, Nonsteroidal; Antimetabolites, Antineoplastic; Antirheumatic Agents; Folic Acid Antagonists; Immunosuppressive AgentsMethotrexate sodium is approved to be used alone or with other drugs to treat:

    Synonyms and trade names

    Methotrexate disodium salt; 7413-34-5; METHOTREXATE SODIUM; Sodium methotrexate; Disodium methotrexate; Abitrexate; Trexall; Methotrexate Lpf; Folex Pfs; Mexate-Aq Preserved; Mexate-Aq; Methotrexate sodium salt; Methotrexate, Sodium Salt; Methotrexate (as disodium); ADX-2191 SODIUM; Methotrexate Preservative Free

    GHS hazard classification

    Reported hazard statementsH301 (100%), H311 (98.1%), H315 (100%), H319 (100%), H331 (98.1%), H335 (98.1%), H340 (98.1%), H360 (100%)

    H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

    H311 (98.1%): Toxic in contact with skin [Danger Acute toxicity, dermal]

    What the public record says

    Methotrexate sodium · CAS 15475-56-6 · C20H20N8Na2O5. UNII 3IG1E710ZN.

    Source: PubChem / Wikidata; the batch COA governs where values differ.

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