美洛昔康（CAS 71125-38-7）：分子式 C14H13N3O4S2、分子量 351.4。
| CAS号 | 71125-38-7 |
|---|---|
| 分子式 | C14H13N3O4S2 |
| 分子量 | 351.4 |
| 熔点 | 256 |
| 沸点 | 581.3±60.0 |
| LogP | 0.1 |
| 应用领域 | Uses: Nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis、primary dysmenorrhea、fever、and as an analgesic ...、THERAP CAT: Anti-inflammatory、THERAP CAT (VET): Anti-inflammatory、Medication、Use (kg、approx.) in Germany (2009): >250、Use (kg) in USA (2002): 809、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Consumption (g per capita) in the USA (2002): 0.00287、Calculated removal (%): 22.6、Used to relieve the symptoms of arthritis、and as an analgesic、especially where there is an inflammatory component.、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Pharmaceuticals -> Animal Drugs -> Approved in Taiwan、Methods of Manufacturing: Reaction of benzothiazolo-3(2H)-one-1、1-dioxide with methyl chloroacetate gives the methyl 2(3H)-acetate derivative、which is isomerized with sodium methoxide in toluene-tert-butanol yielding methyl 4-hydroxy-2H-1、2-benzothiazine-3-carboxylate-1、1-dioxide. Subsequent methylation with methyl iodide in methanol yields the 2-methyl compound. Finally this compound is treated with 2-amino-5-methylthiazole in xylene.、Preparation: G. Trummlitz et al.、DE 2756113 (1979 to Thomae)、eidem、US 4233299 (1980 to Boehringer Ingelheim).、Formulations、Preparations: Formulations: (AHFS、2009) [Table#7407] |
登记用途：Uses: Nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis、primary dysmenorrhea、fever、and as an analgesic ...、THERAP CAT: Anti-inflammatory、THERAP CAT (VET): Anti-inflammatory、Medication、Use (kg、approx.) in Germany (2009): >250、Use (kg) in USA (2002): 809、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Consumption (g per capita) in the USA (2002): 0.00287、Calculated removal (%): 22.6、Used to relieve the symptoms of arthritis、and as an analgesic、especially where there is an inflammatory component.、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Pharmaceuticals -> Animal Drugs -> Approved in Taiwan、Methods of Manufacturing: Reaction of benzothiazolo-3(2H)-one-1、1-dioxide with methyl chloroacetate gives the methyl 2(3H)-acetate derivative、which is isomerized with sodium methoxide in toluene-tert-butanol yielding methyl 4-hydroxy-2H-1、2-benzothiazine-3-carboxylate-1、1-dioxide. Subsequent methylation with methyl iodide in methanol yields the 2-methyl compound. Finally this compound is treated with 2-amino-5-methylthiazole in xylene.、Preparation: G. Trummlitz et al.、DE 2756113 (1979 to Thomae)、eidem、US 4233299 (1980 to Boehringer Ingelheim).、Formulations、Preparations: Formulations: (AHFS、2009) [Table#7407]。
美洛昔康 是一种化工化合物，登记 CAS 号为 71125-38-7，分子式 C14H13N3O4S2（分子量 351.4）。
登记 CAS 号：71125-38-7
其分子式 C14H13N3O4S2 由 14 个碳、13 个氢、3 个氮、4 个氧、2 个硫 组成。
别名/同义词：美洛昔康 · Meloxicam
美洛昔康 的 CAS 登记号为 71125-38-7。
分子式 C14H13N3O4S2，分子量 351.4。
别名/同义词：美洛昔康、Meloxicam。
登记用途：Uses: Nonsteroidal anti-inflammatory drug used to relieve the symptoms of arthritis、primary dysmenorrhea、fever、and as an analgesic ...、THERAP CAT: Anti-inflammatory、THERAP CAT (VET): Anti-inflammatory、Medication、Use (kg、approx.) in Germany (2009): >250、Use (kg) in USA (2002): 809、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Consumption (g per capita) in the USA (2002): 0.00287、Calculated removal (%): 22.6、Used to relieve the symptoms of arthritis、and as an analgesic、especially where there is an inflammatory component.、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Pharmaceuticals -> Animal Drugs -> Approved in Taiwan、Methods of Manufacturing: Reaction of benzothiazolo-3(2H)-one-1、1-dioxide with methyl chloroacetate gives the methyl 2(3H)-acetate derivative、which is isomerized with sodium methoxide in toluene-tert-butanol yielding methyl 4-hydroxy-2H-1、2-benzothiazine-3-carboxylate-1、1-dioxide. Subsequent methylation with methyl iodide in methanol yields the 2-methyl compound. Finally this compound is treated with 2-amino-5-methylthiazole in xylene.、Preparation: G. Trummlitz et al.、DE 2756113 (1979 to Thomae)、eidem、US 4233299 (1980 to Boehringer Ingelheim).、Formulations、Preparations: Formulations: (AHFS、2009) [Table#7407]。
美洛昔康（CAS 71125-38-7）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 71125-38-7 |
|---|---|
| PubChem CID | 54677470 |
| Molecular formula | C14H13N3O4S2 |
| IUPAC name | 4-hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-1,1-dioxo-1λ6,2-benzothiazine-3-carboxamide |
| UNII (FDA) | VG2QF83CGL |
| Molecular Weight | 351.4 |
|---|---|
| XLogP3 | 3 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 7 |
| Rotatable Bond Count | 2 |
| Exact Mass | 351.03474825 |
| Monoisotopic Mass | 351.03474825 |
| Topological Polar Surface Area | 136 |
| Heavy Atom Count | 23 |
| Boiling Point | 581.3±60.0 |
|---|---|
| Melting Point | 256 |
| Melting Point | 254 °C (decomposes) |
| Melting Point | 254 °C |
| Solubility | 22 |
| Solubility | 1.54e-01 g/L |
| LogP | 0.1 |
| LogP | log Kow = 3.54 |
| LogP | 1.9 |
| LogP | 2.34 |
meloxicam; 71125-38-7; Mobic; Metacam; Mobicox; Movalis; Movatec; Mobec; Coxicam; Meloxivet; Melfax; UH-AC 62XX; Meloxicamum; Meloxidolor; Meloxoral; Rheumocam
| GHS notification summary | 0.8% (1 / 118) |
|---|
| GHS notification summary | 0.8% (1 / 118) |
|---|---|
| Reported hazard statements | H301 (95.8%), H360 (50.8%), H412 (56.8%), H372 |
This chemical does not meet GHS hazard criteria for 0.8% (1 of 118) of reports.
H301 (95.8%): Toxic if swallowed [Danger Acute toxicity, oral]
Meloxicam · CAS 71125-38-7 · C14H13N3O4S2. UNII VG2QF83CGL. Boiling Point: 581.3±60.0; Melting Point: 256; Melting Point: 254 °C (decomposes).
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Meloxicam