甲地孕酮(CAS 3562-63-8):分子式 C22H30O3、分子量 342.5。
| CAS号 | 3562-63-8 |
|---|---|
| 分子式 | C22H30O3 |
| 分子量 | 342.5 |
| LogP | 2.6 |
| 应用领域 | Uses: MEDICATION、MEDICATION (VET)、Use (kg、approx.) in Germany (2009): >25、Use (kg) in USA (2002): 5360、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Consumption (g per capita) in the USA (2002): 0.019、Calculated removal (%): 22.5、Methods of Manufacturing: ... Prepared by oxidation of 17alpha-acetoxy-3beta-hydroxy-6-methylpregn-5-en-20-one with aluminium tert-butoxide and para-quinone in dry benzene.、Megestrol acetate、Impurities: Reported impurities include: 6、17a-dimethyl-3、17-dioxo-D-homoandrosta-4、6-dien-17aalpha-yl acetate (D-homo megestrol acetate)、6alpha-methyl-3、20-dioxopregn-4-en-17-yl acetate (medroxyprogesterone acetate)、6-methyl-3、20-dioxopregna-1、4、6-trien-17-yl acetate、6-methylene-3、20-dioxopregn-4-en-17-yl acetate (6-methylene hydroxyprogesterone acetate) and 6-methyl-17-hydroxypregna-4、6-diene-3、20-dione (megestrol).、Formulations、Preparations: Megestrol acetate is commercially available as oral tablets and as oral suspensions、the 2 concentrations of the oral suspensions differ in formulation and are not bioequivalent.、NIAGESTIN、OVABAN. MIXT WITH ETHYNYLESTRADIOL: CO-ERVONUM、KOMBIQUENS、NOVAL、NUVACON、OVEX、PLANOVIN、TRI-ERVONUM、VOLIDAN、WERADYS、MIXT WITH MESTRANOL: DELPREGNIN.、MEGESTROL ACETATE、MEGESTROL ACETATE (MEGACE) IS AVAIL IN 20-MG TABLETS.、ACETATE、Oral: Suspension: 40 mg of micronized megestrol acetate per mL、Megestrol (STAT RX USA LLC)、Oral: Tablets: 20 mg or 40 mg megestrol acetate、Megestrol Acetate (Barr Laboratories Inc).、General Manufacturing Information: Megestrol acetate is a synthetic progestin which differs structurally from progesterone only in the addition of a 6-methyl group on the B ring、a 17-acetoxy group on the D ring of the steroid nucleus、and the addition of a 6-7 double bond. |
登记用途:Uses: MEDICATION、MEDICATION (VET)、Use (kg、approx.) in Germany (2009): >25、Use (kg) in USA (2002): 5360、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Consumption (g per capita) in the USA (2002): 0.019、Calculated removal (%): 22.5、Methods of Manufacturing: ... Prepared by oxidation of 17alpha-acetoxy-3beta-hydroxy-6-methylpregn-5-en-20-one with aluminium tert-butoxide and para-quinone in dry benzene.、Megestrol acetate、Impurities: Reported impurities include: 6、17a-dimethyl-3、17-dioxo-D-homoandrosta-4、6-dien-17aalpha-yl acetate (D-homo megestrol acetate)、6alpha-methyl-3、20-dioxopregn-4-en-17-yl acetate (medroxyprogesterone acetate)、6-methyl-3、20-dioxopregna-1、4、6-trien-17-yl acetate、6-methylene-3、20-dioxopregn-4-en-17-yl acetate (6-methylene hydroxyprogesterone acetate) and 6-methyl-17-hydroxypregna-4、6-diene-3、20-dione (megestrol).、Formulations、Preparations: Megestrol acetate is commercially available as oral tablets and as oral suspensions、the 2 concentrations of the oral suspensions differ in formulation and are not bioequivalent.、NIAGESTIN、OVABAN. MIXT WITH ETHYNYLESTRADIOL: CO-ERVONUM、KOMBIQUENS、NOVAL、NUVACON、OVEX、PLANOVIN、TRI-ERVONUM、VOLIDAN、WERADYS、MIXT WITH MESTRANOL: DELPREGNIN.、MEGESTROL ACETATE、MEGESTROL ACETATE (MEGACE) IS AVAIL IN 20-MG TABLETS.、ACETATE、Oral: Suspension: 40 mg of micronized megestrol acetate per mL、Megestrol (STAT RX USA LLC)、Oral: Tablets: 20 mg or 40 mg megestrol acetate、Megestrol Acetate (Barr Laboratories Inc).、General Manufacturing Information: Megestrol acetate is a synthetic progestin which differs structurally from progesterone only in the addition of a 6-methyl group on the B ring、a 17-acetoxy group on the D ring of the steroid nucleus、and the addition of a 6-7 double bond.。
甲地孕酮 是一种化工化合物,登记 CAS 号为 3562-63-8,分子式 C22H30O3(分子量 342.5)。
登记 CAS 号:3562-63-8
其分子式 C22H30O3 由 22 个碳、30 个氢、3 个氧 组成。
别名/同义词:甲地孕酮 · megestrol
甲地孕酮 的 CAS 登记号为 3562-63-8。
分子式 C22H30O3,分子量 342.5。
别名/同义词:甲地孕酮、megestrol。
登记用途:Uses: MEDICATION、MEDICATION (VET)、Use (kg、approx.) in Germany (2009): >25、Use (kg) in USA (2002): 5360、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Consumption (g per capita) in the USA (2002): 0.019、Calculated removal (%): 22.5、Methods of Manufacturing: ... Prepared by oxidation of 17alpha-acetoxy-3beta-hydroxy-6-methylpregn-5-en-20-one with aluminium tert-butoxide and para-quinone in dry benzene.、Megestrol acetate、Impurities: Reported impurities include: 6、17a-dimethyl-3、17-dioxo-D-homoandrosta-4、6-dien-17aalpha-yl acetate (D-homo megestrol acetate)、6alpha-methyl-3、20-dioxopregn-4-en-17-yl acetate (medroxyprogesterone acetate)、6-methyl-3、20-dioxopregna-1、4、6-trien-17-yl acetate、6-methylene-3、20-dioxopregn-4-en-17-yl acetate (6-methylene hydroxyprogesterone acetate) and 6-methyl-17-hydroxypregna-4、6-diene-3、20-dione (megestrol).、Formulations、Preparations: Megestrol acetate is commercially available as oral tablets and as oral suspensions、the 2 concentrations of the oral suspensions differ in formulation and are not bioequivalent.、NIAGESTIN、OVABAN. MIXT WITH ETHYNYLESTRADIOL: CO-ERVONUM、KOMBIQUENS、NOVAL、NUVACON、OVEX、PLANOVIN、TRI-ERVONUM、VOLIDAN、WERADYS、MIXT WITH MESTRANOL: DELPREGNIN.、MEGESTROL ACETATE、MEGESTROL ACETATE (MEGACE) IS AVAIL IN 20-MG TABLETS.、ACETATE、Oral: Suspension: 40 mg of micronized megestrol acetate per mL、Megestrol (STAT RX USA LLC)、Oral: Tablets: 20 mg or 40 mg megestrol acetate、Megestrol Acetate (Barr Laboratories Inc).、General Manufacturing Information: Megestrol acetate is a synthetic progestin which differs structurally from progesterone only in the addition of a 6-methyl group on the B ring、a 17-acetoxy group on the D ring of the steroid nucleus、and the addition of a 6-7 double bond.。
甲地孕酮(CAS 3562-63-8)的独立参考数据,整理自公开化学数据库。
| CAS Registry Number | 3562-63-8 |
|---|---|
| PubChem CID | 19090 |
| Molecular formula | C22H30O3 |
| IUPAC name | (8R,9S,10R,13S,14S,17R)-17-acetyl-17-hydroxy-6,10,13-trimethyl-2,8,9,11,12,14,15,16-octahydro-1H-cyclopenta[a]phenanthren-3-one |
| UNII (FDA) | EA6LD1M70M |
| Molecular Weight | 342.5 |
|---|---|
| XLogP3 | 2.6 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 1 |
| Exact Mass | 342.21949481 |
| Monoisotopic Mass | 342.21949481 |
| Topological Polar Surface Area | 54.4 |
| Heavy Atom Count | 25 |
| Collision Cross Section | 198.71 Ų [M+H]+ |
|---|---|
| Collision Cross Section | 202.21 Ų [M+Cl]- |
megestrol; 3562-63-8; Megestrolo; Pregna-4,6-diene-3,20-dione, 17-hydroxy-6-methyl-; Chronopil; Megestrolum; EA6LD1M70M; DTXSID001009330; CHEBI:6722; Compound 5071; RefChem:55564; G03AC05; G03DB02; L02AB01; DTXCID001436159; 222-628-6
megestrol · CAS 3562-63-8 · C22H30O3. UNII EA6LD1M70M. Collision Cross Section: 198.71 Ų [M+H]+; Collision Cross Section: 202.21 Ų [M+Cl]-.
数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。
English page: megestrol