乙酰丙酸钙盐二水合物

Description

levulinic acid calcium salt dihydrate · CAS 5743-49-7 · C10H18CaO8. UNII T6133SO781. European Pharmacopoeia monograph.

Identification

CAS Registry Number	5743-49-7
PubChem CID	68651
Molecular formula	C10H18CaO8
IUPAC name	calcium;bis(4-oxopentanoate);dihydrate
UNII (FDA)	T6133SO781
Pharmacopoeial monograph	European Pharmacopoeia monograph

Computed Descriptors

Molecular Weight	306.32
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	8
Rotatable Bond Count	4
Exact Mass	306.0627584
Monoisotopic Mass	306.0627584
Topological Polar Surface Area	116
Heavy Atom Count	19
Formal Charge	0
Complexity	101

Physical description & handling notes

• Dihydrate: Solid; [Merck Index] Solid; [TCI America MSDS]

Documented Uses

• Used as a calcium supplement; May be used in veterinary medicine in hypocalcemic states; [Merck Index]
• This new application of calcium is intended for use as a food fortifier, to fortify foods like sauces, condiments, beer, beverages, soft drinks, milk and milk products, soy milk and soy products with calcium nutrition. Calcium levulinate can be used alone, or with calcium lactate, calcium chloride, and other compounds, either for pharmaceutical tablets, capsules, or injections preparation. In essence, calcium levulinate is ultimately a relatively new calcium supplementation option.
• Calcium leaves the body mainly in urine and feces, but also in other body tissues and fluids, like sweat. Overall, a typical daily calcium loss for a healthy adult man or woman via renal excretion is approximately 5 mmol/day while endogenous fecal calcium losses are about 2.1 mg/kg per day in adults and about 1.4 mg/kg per day in children.
• 99% of the body's calcium supply is stored in the bones and teeth where it supports their structure and function. Elsewhere, 1% or less of this calcium supply is used for essential metabolic functions like vascular contraction and vasodilation, muscle function, nerve transmission, intracellular signaling, and hormonal secretion, among other activities.
• Despite inter-individual differences, general clinical lab tests list some reference calcium clearance values as being considered a 'normal range', like urine calcium as approximately < 250 mg/24 h.
• Readily accessible data regarding the protein binding of calcium levulinate is not available, although many different calcium-binding proteins exist, with different cellular and tissue distribution and involvement in specific biological function. Some of these proteins include calmodulin, calsequestrin, calretinin, and calcineurin, among others.

Synonyms

Calcium levulinate dihydrate; 5743-49-7; DTXSID8046539; T6133SO781; DTXCID6026539; RefChem:1080692; Calcium Levulinate; calcium;4-oxopentanoate;dihydrate; Calcium levulinate (1:2) dihydrate; Pentanoic acid, 4-oxo-,calcium salt, hydrate (2:1:2); Pentanoic acid, 4-oxo-, calcium salt (2:1), dihydrate; CAS-5743-49-7; NCGC00166102-01; UNII-T6133SO781; calcium 4-oxopentanoate dihydrate; Calcium levulinate [USP:INN:BAN]

Frequently Asked Questions

What are the CAS number and molecular formula of levulinic acid calcium salt dihydrate?

CAS 5743-49-7; molecular formula C10H18CaO8; molecular weight — g/mol.

What other names is levulinic acid calcium salt dihydrate known by?

Calcium levulinate dihydrate, 5743-49-7, DTXSID8046539, T6133SO781, DTXCID6026539, RefChem:1080692.

Does levulinic acid calcium salt dihydrate have a pharmacopoeial monograph?

Yes — a monograph exists in the European Pharmacopoeia (Ph. Eur.).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.