拉贝洛尔（CAS 36894-69-6）：分子式 C19H24N2O3、分子量 328.4。
| CAS号 | 36894-69-6 |
|---|---|
| 分子式 | C19H24N2O3 |
| 分子量 | 328.4 |
| 熔点 | 188 |
| 沸点 | 552.7 |
| LogP | 2.7 |
| 应用领域 | Uses: MEDICATION、Use (kg) in USA (2002): 1980、Consumption (g per capita) in the USA (2002): 0.00702、Excretion rate: 0.04、Calculated removal (%): 32.1、For the management of hypertension (alone or in combination with other classes of antihypertensive agents)、as well as chronic stable angina pectoris and sympathetic overactivity syndrome associated with severe tetanus. Labetalol is used parenterally for immediate reduction in blood pressure in severe hypertension or in hypertensive crises when considered an emergency、for the control of blood pressure in patients with pheochromocytoma and pregnant women with preeclampsia、and to produce controlled hypotension during anesthesia to reduce bleeding resulting from surgical procedures.、Use Classification: Pharmaceuticals、Formulations、Preparations: Oral Tablets、film coated、100 mg、Normodyne (with parabens、scored)、Schering、Trandate (with parabens: scored)、Allen & Hanburys、200 mg、Normodyne (with parabens: scored)、Trandate (with parabens、300 mg、Normodyne (with parabens)、Trandate (with aprabens、Allen & Hanburys.、Labetalol hydrochloride、Parenteral Injection、for IV use、5 mg、ml、Normodyne (with anhydrous dextrose 15 mg、edetate disodium、and parabens)、Trandate (with anhydrous dextrosse 45 mg ml、edetate disodium and parabens)、Oral Tablets film coated、100 mg with Hydrochlorothiazide 25 mg、Normozide 100、25 (with parabens)、Trandate HCT 9 with parabens)、200 mg with Hydrochlorothiazide 25 mg、Normozide 200、Trandate HCT (with parabens)、300 mg withHydrochlorothiazide 25 mg、Normozide 300、Labetalol Hydrochloride Combinations |
登记用途：Uses: MEDICATION、Use (kg) in USA (2002): 1980、Consumption (g per capita) in the USA (2002): 0.00702、Excretion rate: 0.04、Calculated removal (%): 32.1、For the management of hypertension (alone or in combination with other classes of antihypertensive agents)、as well as chronic stable angina pectoris and sympathetic overactivity syndrome associated with severe tetanus. Labetalol is used parenterally for immediate reduction in blood pressure in severe hypertension or in hypertensive crises when considered an emergency、for the control of blood pressure in patients with pheochromocytoma and pregnant women with preeclampsia、and to produce controlled hypotension during anesthesia to reduce bleeding resulting from surgical procedures.、Use Classification: Pharmaceuticals、Formulations、Preparations: Oral Tablets、film coated、100 mg、Normodyne (with parabens、scored)、Schering、Trandate (with parabens: scored)、Allen & Hanburys、200 mg、Normodyne (with parabens: scored)、Trandate (with parabens、300 mg、Normodyne (with parabens)、Trandate (with aprabens、Allen & Hanburys.、Labetalol hydrochloride、Parenteral Injection、for IV use、5 mg、ml、Normodyne (with anhydrous dextrose 15 mg、edetate disodium、and parabens)、Trandate (with anhydrous dextrosse 45 mg ml、edetate disodium and parabens)、Oral Tablets film coated、100 mg with Hydrochlorothiazide 25 mg、Normozide 100、25 (with parabens)、Trandate HCT 9 with parabens)、200 mg with Hydrochlorothiazide 25 mg、Normozide 200、Trandate HCT (with parabens)、300 mg withHydrochlorothiazide 25 mg、Normozide 300、Labetalol Hydrochloride Combinations。
拉贝洛尔 是一种化工化合物，登记 CAS 号为 36894-69-6，分子式 C19H24N2O3（分子量 328.4）。
登记 CAS 号：36894-69-6
其分子式 C19H24N2O3 由 19 个碳、24 个氢、2 个氮、3 个氧 组成。
别名/同义词：拉贝洛尔 · Labetalol
拉贝洛尔 的 CAS 登记号为 36894-69-6。
分子式 C19H24N2O3，分子量 328.4。
别名/同义词：拉贝洛尔、Labetalol。
登记用途：Uses: MEDICATION、Use (kg) in USA (2002): 1980、Consumption (g per capita) in the USA (2002): 0.00702、Excretion rate: 0.04、Calculated removal (%): 32.1、For the management of hypertension (alone or in combination with other classes of antihypertensive agents)、as well as chronic stable angina pectoris and sympathetic overactivity syndrome associated with severe tetanus. Labetalol is used parenterally for immediate reduction in blood pressure in severe hypertension or in hypertensive crises when considered an emergency、for the control of blood pressure in patients with pheochromocytoma and pregnant women with preeclampsia、and to produce controlled hypotension during anesthesia to reduce bleeding resulting from surgical procedures.、Use Classification: Pharmaceuticals、Formulations、Preparations: Oral Tablets、film coated、100 mg、Normodyne (with parabens、scored)、Schering、Trandate (with parabens: scored)、Allen & Hanburys、200 mg、Normodyne (with parabens: scored)、Trandate (with parabens、300 mg、Normodyne (with parabens)、Trandate (with aprabens、Allen & Hanburys.、Labetalol hydrochloride、Parenteral Injection、for IV use、5 mg、ml、Normodyne (with anhydrous dextrose 15 mg、edetate disodium、and parabens)、Trandate (with anhydrous dextrosse 45 mg ml、edetate disodium and parabens)、Oral Tablets film coated、100 mg with Hydrochlorothiazide 25 mg、Normozide 100、25 (with parabens)、Trandate HCT 9 with parabens)、200 mg with Hydrochlorothiazide 25 mg、Normozide 200、Trandate HCT (with parabens)、300 mg withHydrochlorothiazide 25 mg、Normozide 300、Labetalol Hydrochloride Combinations。
拉贝洛尔（CAS 36894-69-6）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 36894-69-6 |
|---|---|
| PubChem CID | 3869 |
| Molecular formula | C19H24N2O3 |
| IUPAC name | 2-hydroxy-5-[1-hydroxy-2-(4-phenylbutan-2-ylamino)ethyl]benzamide |
| UNII (FDA) | R5H8897N95 |
| Molecular Weight | 328.4 |
|---|---|
| XLogP3 | 3.1 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 8 |
| Exact Mass | 328.17869263 |
| Monoisotopic Mass | 328.17869263 |
| Topological Polar Surface Area | 95.6 |
| Heavy Atom Count | 24 |
| Boiling Point | 552.7 |
|---|---|
| Melting Point | 188 |
| Melting Point | 195 - 196 °C |
| Solubility | 5.78e-03 g/L |
| LogP | 2.7 |
| LogP | 1.89 |
| Dissociation Constants | 7.4 |
| Dissociation Constants | 9.3 |
| Dissociation Constants | pKa = 9.3 |
labetalol; 36894-69-6; Labetolol; Ibidomide; Albetol; Labetalolum; 2-Hydroxy-5-(1-hydroxy-2-((4-phenylbutan-2-yl)amino)ethyl)benzamide; AH 5158; 5-(1-Hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl)salicylamide; 2-hydroxy-5-{1-hydroxy-2-[(4-phenylbutan-2-yl)amino]ethyl}benzamide; 3-Carboxamido-4-hydroxy-alpha-((1-methyl-3-phenylpropylamino)methyl)benzyl alcohol; AH-5158A FREE BASE; CHEBI:6343; SCH-15719W FREE BASE; 2-Hydroxy-5-(1-hydroxy-2-((1-methyl-3-phenylpropyl)amino)ethyl)benzamide; R5H8897N95
| Reported hazard statements | H315 (100%), H319 (100%), H335 (100%), H361 (100%), H411 (66.7%) |
|---|
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
Labetalol · CAS 36894-69-6 · C19H24N2O3. UNII R5H8897N95. Boiling Point: 552.7; Melting Point: 188; Melting Point: 195 - 196 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Labetalol