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L-薄荷醇

CAS 2216-51-5C10H20OMW 156.26

L-薄荷醇(CAS 2216-51-5):分子式 C10H20O、分子量 156.26。

产品概览

CAS号2216-51-5
分子式C10H20O
分子量156.26
熔点100 °F (NTP, 1992)
沸点421 °F at 760 mmHg (NTP, 1992)
LogP3
应用领域Uses: Found in peppermint oil and other mint oils、Used as a flavor、fragrance in liqueurs、confectionary、perfumes、cigarettes、cough drops、and nasal inhalers、Also used as a topical antipruritic and veterinary local anesthetic、antiseptic、carminative、and gastric sedative、[Merck Index] Used in Canada to control mites and in Europe in paints and lacquers、adhesives、metal care products、cleaning products、shoe and leather care products、disinfectants、solvents、repellents、cosmetics、odor agents、and animal care products、[OECD SIDS]、Painting (Solvents) [Category: Paint]、Working with Glues and Adhesives [Category: Other]、Using Disinfectants or Biocides [Category: Clean]、Medication: topical antipruritic、medication (Vet): has been used as a mild local anesthetic、antiseptic & internally as a carminative & gastric sedative、Menthol、IN CHEWING GUM、CHEST RUBS、MENTHOL、AS AN INGREDIENT IN PREPARATIONS FOR THE NOSE & THROAT、IN OINTMENTS TO RELIEVE LOCAL IRRITATIONS OR FOR COUNTERIRRITANT PURPOSES、IN THROAT LOZENGES、ANTIPRURITIC、MEDICATION、Menthol has local anesthetic and counterirritant qualities、and it is widely used to relieve minor throat irritation. Menthol is also used to prepare menthyl esters to emphasize floral notes (especially rose) (L1263). Used to treat occasional minor irritation、pain、sore mouth、and sore throat as well as cough associated with a cold or inhaled irritants.、Use Classification: Fragrance Ingredients、Flavoring Agents -> JECFA Flavorings Index、Industry Uses: Flavoring and nutrient、Odor agents、Fragrance、Fixing agent (mordant)、Consumer Uses: Fragrance、Flavoring and nutrient、Household Products: Cosmetics product ingredient: Menthol (dl-menthol、l-menthol、d-menthol)、Menthol is a fragrance allergen. Fragrance allergens are hazardous only to individuals who suffer from fragrance allergies. The Cosmetic Fragrance and Flavor Ingredient Right to Know Act of 2020 requires fragrance allergens included in Annex III of the EU Cosmetics Regulation No. 1223、2009 be reported to the California Department of Public Health. Fragrance allergens are only required to be reported if present in a rinse-off cosmetic product at a concentration at or above 0.01 percent (100 parts per million) or in a leave-on cosmetic product at a concentration at or above 0.001 percent (10 parts per million).、For more information、you can visit the fragrance allergens webpage on the California Safe Cosmetics Program website:、https:、www.cdph.ca.gov、Programs、CCDPHP、DEODC、OHB、CSCP、Pages、FragranceAllergens.aspx、Product count: 1285、Information on 42 consumer products that contain Menthol、L- in the following categories is provided:、• Commercial、Institutional、• Inside the Home、• Personal Care、• Pet Care、Information on 35 consumer products that contain Menthol (Racementhol) in the following categories is provided:、Methods of Manufacturing: Obtained from peppermint oil or other mint oils、or prepared synthetically by hydrogenation of thymol.、A synthetic process for menthol involves the hydrogenation of thymol or 3-hydroxy-p-cymene which can be obtained from essential oils are produced synthetically from p-cymene (isopropypltoluene) or meta-cresol、Formulations、Preparations: GRADES: TECHNICAL、USP、FCC、Synthetic menthol is available as the optically active levo-menthol with a purity of 99.9%、Present in、cigarettes and pipe tobacco (0.1-0.45%) shaving creams、pre- and aftershave lotions (0.2-0.3%)、toothpastes (0.5%)、mouthwashes (1-2%)、chewing gums (0.5%)、cough drops (0.1%)、refreshing towels (1%)、rubbing alcohol (1-1.2%)、and shampoos (2-0.5%)、menthol primary (L)-isomer、Mentholatum Deep Heating Rub、contains、5.9% Menthol、Mentholatum ointment、1.35%、Mentholatum Deep Heating Lotion、6%、Consumption Patterns: Cigarettes and Tobacco、60%、Salves and lotions、15%、Oral products、12%、Shaving products、Confectionary products、3%、Misc 5% (1981)、U.S. Production: 2023: 10、000、000 - <25、000 lb、2022: 10、2021: 10、2020: 10、2023: 1、000 - <8、500、2022: 1、2021: 1、2020: 1、(1980) 2.63X10+8 g、U.S. Imports: (1984) 1.46x10+9 g、U.S. Exports: (1986) No Data、General Manufacturing Information: Soap、Cleaning Compound、and Toilet Preparation Manufacturing、All Other Chemical Product and Preparation Manufacturing、Not Known or Reasonably Ascertainable、Food、beverage、and tobacco product manufacturing、Other (requires additional information)、All Other Basic Organic Chemical Manufacturing、Soap、Cyclohexanol、5-methyl-2-(1-methylethyl)-、(1R、2S、5R)-rel-: ACTIVE、5R)-: ACTIVE、USP does not distinguish between L-menthol and DL-menthol.、Incompatibilities: butylchloral hydrate、camphor、phenol、chloral hydrate、exalgine、betanaphthol、resorcinol or thymol in triturations、potassium permanganate、chromium trioxide、pyrogallol.、INCOMPATIBILITIES: IT IS THROWN OUT OF AN ALCOHOLIC SOLUTION AS AN OILY LIQUID BY THE ADDITION OF WATER.、CONCENTRATION IN FINAL PRODUCT (%): SOAP: USUAL 0.02、MAX 0.2、DETERGENT: USUAL 0.002、MAX 0.02、CREAMS、LOTIONS: USUAL 0.01、MAX 0.05、PERFUME: USUAL 0.04、MAX 0.3.、FEMA NUMBER 2665

应用领域

登记用途:Uses: Found in peppermint oil and other mint oils、Used as a flavor、fragrance in liqueurs、confectionary、perfumes、cigarettes、cough drops、and nasal inhalers、Also used as a topical antipruritic and veterinary local anesthetic、antiseptic、carminative、and gastric sedative、[Merck Index] Used in Canada to control mites and in Europe in paints and lacquers、adhesives、metal care products、cleaning products、shoe and leather care products、disinfectants、solvents、repellents、cosmetics、odor agents、and animal care products、[OECD SIDS]、Painting (Solvents) [Category: Paint]、Working with Glues and Adhesives [Category: Other]、Using Disinfectants or Biocides [Category: Clean]、Medication: topical antipruritic、medication (Vet): has been used as a mild local anesthetic、antiseptic & internally as a carminative & gastric sedative、Menthol、IN CHEWING GUM、CHEST RUBS、MENTHOL、AS AN INGREDIENT IN PREPARATIONS FOR THE NOSE & THROAT、IN OINTMENTS TO RELIEVE LOCAL IRRITATIONS OR FOR COUNTERIRRITANT PURPOSES、IN THROAT LOZENGES、ANTIPRURITIC、MEDICATION、Menthol has local anesthetic and counterirritant qualities、and it is widely used to relieve minor throat irritation. Menthol is also used to prepare menthyl esters to emphasize floral notes (especially rose) (L1263). Used to treat occasional minor irritation、pain、sore mouth、and sore throat as well as cough associated with a cold or inhaled irritants.、Use Classification: Fragrance Ingredients、Flavoring Agents -> JECFA Flavorings Index、Industry Uses: Flavoring and nutrient、Odor agents、Fragrance、Fixing agent (mordant)、Consumer Uses: Fragrance、Flavoring and nutrient、Household Products: Cosmetics product ingredient: Menthol (dl-menthol、l-menthol、d-menthol)、Menthol is a fragrance allergen. Fragrance allergens are hazardous only to individuals who suffer from fragrance allergies. The Cosmetic Fragrance and Flavor Ingredient Right to Know Act of 2020 requires fragrance allergens included in Annex III of the EU Cosmetics Regulation No. 1223、2009 be reported to the California Department of Public Health. Fragrance allergens are only required to be reported if present in a rinse-off cosmetic product at a concentration at or above 0.01 percent (100 parts per million) or in a leave-on cosmetic product at a concentration at or above 0.001 percent (10 parts per million).、For more information、you can visit the fragrance allergens webpage on the California Safe Cosmetics Program website:、https:、www.cdph.ca.gov、Programs、CCDPHP、DEODC、OHB、CSCP、Pages、FragranceAllergens.aspx、Product count: 1285、Information on 42 consumer products that contain Menthol、L- in the following categories is provided:、• Commercial、Institutional、• Inside the Home、• Personal Care、• Pet Care、Information on 35 consumer products that contain Menthol (Racementhol) in the following categories is provided:、Methods of Manufacturing: Obtained from peppermint oil or other mint oils、or prepared synthetically by hydrogenation of thymol.、A synthetic process for menthol involves the hydrogenation of thymol or 3-hydroxy-p-cymene which can be obtained from essential oils are produced synthetically from p-cymene (isopropypltoluene) or meta-cresol、Formulations、Preparations: GRADES: TECHNICAL、USP、FCC、Synthetic menthol is available as the optically active levo-menthol with a purity of 99.9%、Present in、cigarettes and pipe tobacco (0.1-0.45%) shaving creams、pre- and aftershave lotions (0.2-0.3%)、toothpastes (0.5%)、mouthwashes (1-2%)、chewing gums (0.5%)、cough drops (0.1%)、refreshing towels (1%)、rubbing alcohol (1-1.2%)、and shampoos (2-0.5%)、menthol primary (L)-isomer、Mentholatum Deep Heating Rub、contains、5.9% Menthol、Mentholatum ointment、1.35%、Mentholatum Deep Heating Lotion、6%、Consumption Patterns: Cigarettes and Tobacco、60%、Salves and lotions、15%、Oral products、12%、Shaving products、Confectionary products、3%、Misc 5% (1981)、U.S. Production: 2023: 10、000、000 - <25、000 lb、2022: 10、2021: 10、2020: 10、2023: 1、000 - <8、500、2022: 1、2021: 1、2020: 1、(1980) 2.63X10+8 g、U.S. Imports: (1984) 1.46x10+9 g、U.S. Exports: (1986) No Data、General Manufacturing Information: Soap、Cleaning Compound、and Toilet Preparation Manufacturing、All Other Chemical Product and Preparation Manufacturing、Not Known or Reasonably Ascertainable、Food、beverage、and tobacco product manufacturing、Other (requires additional information)、All Other Basic Organic Chemical Manufacturing、Soap、Cyclohexanol、5-methyl-2-(1-methylethyl)-、(1R、2S、5R)-rel-: ACTIVE、5R)-: ACTIVE、USP does not distinguish between L-menthol and DL-menthol.、Incompatibilities: butylchloral hydrate、camphor、phenol、chloral hydrate、exalgine、betanaphthol、resorcinol or thymol in triturations、potassium permanganate、chromium trioxide、pyrogallol.、INCOMPATIBILITIES: IT IS THROWN OUT OF AN ALCOHOLIC SOLUTION AS AN OILY LIQUID BY THE ADDITION OF WATER.、CONCENTRATION IN FINAL PRODUCT (%): SOAP: USUAL 0.02、MAX 0.2、DETERGENT: USUAL 0.002、MAX 0.02、CREAMS、LOTIONS: USUAL 0.01、MAX 0.05、PERFUME: USUAL 0.04、MAX 0.3.、FEMA NUMBER 2665。

技术档案

这个产品是什么

L-薄荷醇 是一种化工化合物,登记 CAS 号为 2216-51-5,分子式 C10H20O(分子量 156.26)。

识别信息

登记 CAS 号:2216-51-5

其分子式 C10H20O 由 10 个碳、20 个氢、1 个氧 组成。

别名/同义词:L-薄荷醇 · L-MENTHOL

常见问题

L-薄荷醇 的 CAS 号是多少?

L-薄荷醇 的 CAS 登记号为 2216-51-5。

L-薄荷醇 的分子式与分子量是多少?

分子式 C10H20O,分子量 156.26。

L-薄荷醇 还有哪些别名?

别名/同义词:L-薄荷醇、L-MENTHOL。

L-薄荷醇 的登记用途是什么?

登记用途:Uses: Found in peppermint oil and other mint oils、Used as a flavor、fragrance in liqueurs、confectionary、perfumes、cigarettes、cough drops、and nasal inhalers、Also used as a topical antipruritic and veterinary local anesthetic、antiseptic、carminative、and gastric sedative、[Merck Index] Used in Canada to control mites and in Europe in paints and lacquers、adhesives、metal care products、cleaning products、shoe and leather care products、disinfectants、solvents、repellents、cosmetics、odor agents、and animal care products、[OECD SIDS]、Painting (Solvents) [Category: Paint]、Working with Glues and Adhesives [Category: Other]、Using Disinfectants or Biocides [Category: Clean]、Medication: topical antipruritic、medication (Vet): has been used as a mild local anesthetic、antiseptic & internally as a carminative & gastric sedative、Menthol、IN CHEWING GUM、CHEST RUBS、MENTHOL、AS AN INGREDIENT IN PREPARATIONS FOR THE NOSE & THROAT、IN OINTMENTS TO RELIEVE LOCAL IRRITATIONS OR FOR COUNTERIRRITANT PURPOSES、IN THROAT LOZENGES、ANTIPRURITIC、MEDICATION、Menthol has local anesthetic and counterirritant qualities、and it is widely used to relieve minor throat irritation. Menthol is also used to prepare menthyl esters to emphasize floral notes (especially rose) (L1263). Used to treat occasional minor irritation、pain、sore mouth、and sore throat as well as cough associated with a cold or inhaled irritants.、Use Classification: Fragrance Ingredients、Flavoring Agents -> JECFA Flavorings Index、Industry Uses: Flavoring and nutrient、Odor agents、Fragrance、Fixing agent (mordant)、Consumer Uses: Fragrance、Flavoring and nutrient、Household Products: Cosmetics product ingredient: Menthol (dl-menthol、l-menthol、d-menthol)、Menthol is a fragrance allergen. Fragrance allergens are hazardous only to individuals who suffer from fragrance allergies. The Cosmetic Fragrance and Flavor Ingredient Right to Know Act of 2020 requires fragrance allergens included in Annex III of the EU Cosmetics Regulation No. 1223、2009 be reported to the California Department of Public Health. Fragrance allergens are only required to be reported if present in a rinse-off cosmetic product at a concentration at or above 0.01 percent (100 parts per million) or in a leave-on cosmetic product at a concentration at or above 0.001 percent (10 parts per million).、For more information、you can visit the fragrance allergens webpage on the California Safe Cosmetics Program website:、https:、www.cdph.ca.gov、Programs、CCDPHP、DEODC、OHB、CSCP、Pages、FragranceAllergens.aspx、Product count: 1285、Information on 42 consumer products that contain Menthol、L- in the following categories is provided:、• Commercial、Institutional、• Inside the Home、• Personal Care、• Pet Care、Information on 35 consumer products that contain Menthol (Racementhol) in the following categories is provided:、Methods of Manufacturing: Obtained from peppermint oil or other mint oils、or prepared synthetically by hydrogenation of thymol.、A synthetic process for menthol involves the hydrogenation of thymol or 3-hydroxy-p-cymene which can be obtained from essential oils are produced synthetically from p-cymene (isopropypltoluene) or meta-cresol、Formulations、Preparations: GRADES: TECHNICAL、USP、FCC、Synthetic menthol is available as the optically active levo-menthol with a purity of 99.9%、Present in、cigarettes and pipe tobacco (0.1-0.45%) shaving creams、pre- and aftershave lotions (0.2-0.3%)、toothpastes (0.5%)、mouthwashes (1-2%)、chewing gums (0.5%)、cough drops (0.1%)、refreshing towels (1%)、rubbing alcohol (1-1.2%)、and shampoos (2-0.5%)、menthol primary (L)-isomer、Mentholatum Deep Heating Rub、contains、5.9% Menthol、Mentholatum ointment、1.35%、Mentholatum Deep Heating Lotion、6%、Consumption Patterns: Cigarettes and Tobacco、60%、Salves and lotions、15%、Oral products、12%、Shaving products、Confectionary products、3%、Misc 5% (1981)、U.S. Production: 2023: 10、000、000 - <25、000 lb、2022: 10、2021: 10、2020: 10、2023: 1、000 - <8、500、2022: 1、2021: 1、2020: 1、(1980) 2.63X10+8 g、U.S. Imports: (1984) 1.46x10+9 g、U.S. Exports: (1986) No Data、General Manufacturing Information: Soap、Cleaning Compound、and Toilet Preparation Manufacturing、All Other Chemical Product and Preparation Manufacturing、Not Known or Reasonably Ascertainable、Food、beverage、and tobacco product manufacturing、Other (requires additional information)、All Other Basic Organic Chemical Manufacturing、Soap、Cyclohexanol、5-methyl-2-(1-methylethyl)-、(1R、2S、5R)-rel-: ACTIVE、5R)-: ACTIVE、USP does not distinguish between L-menthol and DL-menthol.、Incompatibilities: butylchloral hydrate、camphor、phenol、chloral hydrate、exalgine、betanaphthol、resorcinol or thymol in triturations、potassium permanganate、chromium trioxide、pyrogallol.、INCOMPATIBILITIES: IT IS THROWN OUT OF AN ALCOHOLIC SOLUTION AS AN OILY LIQUID BY THE ADDITION OF WATER.、CONCENTRATION IN FINAL PRODUCT (%): SOAP: USUAL 0.02、MAX 0.2、DETERGENT: USUAL 0.002、MAX 0.02、CREAMS、LOTIONS: USUAL 0.01、MAX 0.05、PERFUME: USUAL 0.04、MAX 0.3.、FEMA NUMBER 2665。

PubChem 公开数据

L-薄荷醇(CAS 2216-51-5)的独立参考数据,整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number2216-51-5
PubChem CID16666
Molecular formulaC10H20O
IUPAC name(1R,2S,5R)-5-methyl-2-propan-2-ylcyclohexan-1-ol
UNII (FDA)YS08XHA860
FEMA number2665
JECFA number427

计算分子描述符

Molecular Weight156.26
XLogP33
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count1
Rotatable Bond Count1
Exact Mass156.151415257
Monoisotopic Mass156.151415257
Topological Polar Surface Area20.2
Heavy Atom Count11

在册的理化数值

Boiling Point421 °F at 760 mmHg (NTP, 1992)
Boiling Point212
Boiling Point212 °C
Boiling Point212 °C ((-)-isomer 216.5)
Melting Point100 °F (NTP, 1992)
Melting Point43
Melting Point41-43 °C
Melting Point43 °C
Flash Point196 °F (NTP, 1992)
Solubility490

在册的记载用途

    Painting (Solvents) [Category: Paint]Working with Glues and Adhesives [Category: Other]

    同义词与商品名

    l-Menthol; (-)-menthol; 2216-51-5; Levomenthol; l-(-)-Menthol; (-)-Menthyl alcohol; Levomentholum; U.S.P. Menthol; (1R)-(-)-Menthol; (-)-(1R,3R,4S)-Menthol; D-(-)-Menthol; (-)-trans-p-Menthan-cis-ol; levomentol; (1R,2S,5R)-5-methyl-2-(propan-2-yl)cyclohexan-1-ol; Menthol, (1R,3R,4S)-(-)-; (1R,3R,4S)-(-)-MENTHOL

    已收录的法规名录

    Regulatory & Food ContactFlavoring Agents
    Mint, Cool
    CIR / INCI: Cosmetics ingredient -> Buffering/pH Adjusting; Conditioning/Emollient; Flavor; Fragrance; Other (Specify)
    GHS notification summary0.3% (7 / 2060)

    GHS 危害分类

    GHS notification summary0.3% (7 / 2060)
    Reported hazard statementsH315 (97.6%), H319 (31.9%), H320, H336, H402

    This chemical does not meet GHS hazard criteria for 0.3% (7 of 2060) of reports.

    H315 (97.6%): Causes skin irritation [Warning Skin corrosion/irritation]

    公开数据库对它的描述

    L-MENTHOL · CAS 2216-51-5 · C10H20O. UNII YS08XHA860. Boiling Point: 421 °F at 760 mmHg (NTP, 1992); Boiling Point: 212; Boiling Point: 212 °C.

    物理形态与操作说明

    数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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