酮替芬

CAS 34580-13-7C19H19NOSMW 309.4

酮替芬（CAS 34580-13-7）：分子式 C19H19NOS、分子量 309.4。

产品概览

CAS号	34580-13-7
分子式	C19H19NOS
分子量	309.4
熔点	304 to 307 °F (NTP, 1992)
LogP	2.2
应用领域	Uses: MEDICATION: Antiasthmatic、Use Classification: Pharmaceuticals、Formulations、Preparations: Ophthalmic: Solution 0.025% Zaditor (with benzalkonium chloride)、(Novartis).、Each mL of Zaditor contains: 0.345 mg ketotifen fumarate equivalent to 0.25 mg ketotifen.、Ketotifen Fumarate、General Manufacturing Information: Preparation: J.P. Bourquin、DE 2111071 coresponding to US 3682930 (1971、1972 both to Sandoz)、Information available in 2004 indicated that Ketotifen was used in the manufacture of pharmaceutical preparations in the following countries: Algeria、Argentina、Bahrain、Brazil、Chile、Colombia、Dominican Republic、Ecuador、Egypt、Iraq、Jordan、Kuwait、Lebanon、Libyan Arab Jamahiriya、Luxembourg、New Zealand、Oman、Poland、Qatar、Romania、Saudi Arabia、Singapore、Spain、Sudan、Syrian Arab Republic、Thailand、Tunisia、Turkey、United Arab Emirates、Yemen、Yugoslavia、Information available in 2004 indicated that Ketotifen fumarate was used in the manufacture of pharmaceutical preparations in the following countries: Algeria、Austria、Bahamas、Bangladesh、Barbados、Belgium、Bermuda、Bulgaria、Canada、Cayman Islands、Costa Rica、Cyprus、Czech Republic、Denmark、El Salvador、Ethiopia、Finland、France、Germany、Ghana、Greece、Guatemala、Guyana、Haiti、Honduras、Hong Kong、Hungary、India、Indonesia、Ireland、Israel、Italy、Jamaica、Kenya、Malaysia、Malta、Mexico、Netherlands、Netherlands Antilles、Nicaragua、Nigeria、Norway、Panama、Portugal、Russian Federation、Slovenia、South Africa、Sweden、Switzerland、United Kingdom、United Republic of Tanzania、USA、Zimbabwe (1、2)、Ketotifen fumarate

应用领域

登记用途：Uses: MEDICATION: Antiasthmatic、Use Classification: Pharmaceuticals、Formulations、Preparations: Ophthalmic: Solution 0.025% Zaditor (with benzalkonium chloride)、(Novartis).、Each mL of Zaditor contains: 0.345 mg ketotifen fumarate equivalent to 0.25 mg ketotifen.、Ketotifen Fumarate、General Manufacturing Information: Preparation: J.P. Bourquin、DE 2111071 coresponding to US 3682930 (1971、1972 both to Sandoz)、Information available in 2004 indicated that Ketotifen was used in the manufacture of pharmaceutical preparations in the following countries: Algeria、Argentina、Bahrain、Brazil、Chile、Colombia、Dominican Republic、Ecuador、Egypt、Iraq、Jordan、Kuwait、Lebanon、Libyan Arab Jamahiriya、Luxembourg、New Zealand、Oman、Poland、Qatar、Romania、Saudi Arabia、Singapore、Spain、Sudan、Syrian Arab Republic、Thailand、Tunisia、Turkey、United Arab Emirates、Yemen、Yugoslavia、Information available in 2004 indicated that Ketotifen fumarate was used in the manufacture of pharmaceutical preparations in the following countries: Algeria、Austria、Bahamas、Bangladesh、Barbados、Belgium、Bermuda、Bulgaria、Canada、Cayman Islands、Costa Rica、Cyprus、Czech Republic、Denmark、El Salvador、Ethiopia、Finland、France、Germany、Ghana、Greece、Guatemala、Guyana、Haiti、Honduras、Hong Kong、Hungary、India、Indonesia、Ireland、Israel、Italy、Jamaica、Kenya、Malaysia、Malta、Mexico、Netherlands、Netherlands Antilles、Nicaragua、Nigeria、Norway、Panama、Portugal、Russian Federation、Slovenia、South Africa、Sweden、Switzerland、United Kingdom、United Republic of Tanzania、USA、Zimbabwe (1、2)、Ketotifen fumarate。

技术档案

这个产品是什么

酮替芬是一种化工化合物，登记 CAS 号为 34580-13-7，分子式 C19H19NOS（分子量 309.4）。

识别信息

登记 CAS 号：34580-13-7

其分子式 C19H19NOS 由 19 个碳、19 个氢、1 个氮、1 个氧、1 个硫组成。

别名/同义词：酮替芬 · Ketotifen

常见问题

酮替芬的 CAS 号是多少？

酮替芬的 CAS 登记号为 34580-13-7。

酮替芬的分子式与分子量是多少？

分子式 C19H19NOS，分子量 309.4。

酮替芬还有哪些别名？

别名/同义词：酮替芬、Ketotifen。

酮替芬的登记用途是什么？

PubChem 公开数据

酮替芬（CAS 34580-13-7）的独立参考数据，整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number	34580-13-7
PubChem CID	3827
Molecular formula	C19H19NOS
IUPAC name	2-(1-methylpiperidin-4-ylidene)-6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-8-one
UNII (FDA)	X49220T18G

计算分子描述符

Molecular Weight	309.4
XLogP3	3.2
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	0
Exact Mass	309.11873540
Monoisotopic Mass	309.11873540
Topological Polar Surface Area	48.6
Heavy Atom Count	22

在册的理化数值

Melting Point	304 to 307 °F (NTP, 1992)
Melting Point	190
Melting Point	152-153 °C
Melting Point	191 °C (fumarate salt)
Solubility	7.87e-03 g/L
LogP	2.2
Dissociation Constants	8.43 ± 0.11

在册的记载用途

同义词与商品名

ketotifen; 34580-13-7; Ketotifene; Ketotifeno; Ketotifenum; HC 20-511; DTXSID7023190; 4,9-Dihydro-4-(1-methyl-4-piperidinylidene)-10H-benzo(4,5)cyclohepta(1,2-b)thiophen-10-one; X49220T18G; DTXCID203190; CHEBI:92511; 10H-Benzo[4,5]cyclohepta[1,2-b]thiophen-10-one, 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-; 4,9-dihydro-4-(1-methyl-4-piperidinylidene)-10h-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one; Ketotiphene; Ketotiphen; 10-(1-methylpiperidin-4-ylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one

已收录的法规名录

GHS notification summary	50% (1 / 2)

GHS 危害分类

GHS notification summary	50% (1 / 2)
Reported hazard statements	H302 (50%)

This chemical does not meet GHS hazard criteria for 50% (1 of 2) of reports.

H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral]

公开数据库对它的描述

Ketotifen · CAS 34580-13-7 · C19H19NOS. UNII X49220T18G. Melting Point: 304 to 307 °F (NTP, 1992); Melting Point: 190; Melting Point: 152-153 °C.

物理形态与操作说明

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。

酮替芬