衣康酸（CAS 97-65-4）：分子式 C5H6O4、分子量 130.10。
| CAS号 | 97-65-4 |
|---|---|
| 分子式 | C5H6O4 |
| 分子量 | 130.10 |
| 熔点 | 175 °C |
| 沸点 | 268 °C, SUBLIMES |
| LogP | -0.1 |
| 应用领域 | Uses: Used in copolymerization and to make resins、plasticizers、and lube oil additives、[HSDB] Used as a comonomer in the production of acrylic fibers and latex、[eChemPortal: SIDSUNEP]、COPOLYMERIZATIONS、RESINS、PLASTICIZERS、LUBE OIL ADDITIVES、INTERMEDIATE、Industry Uses: Surface modifier、Intermediate、Not Known or Reasonably Ascertainable、Monomers、Consumer Uses: Not Known or Reasonably Ascertainable、Household Products: Information on 1 consumer products that contain Methylenesuccinic acid in the following categories is provided:、• Auto Products、Methods of Manufacturing: OBTAINED BY DRY DISTILLATION OF CITRIC ACID AND SUBSEQUENT TREATMENT OF THE ANHYDRIDE WITH WATER. PRODUCED ON A LARGE SCALE BY SUBMERGED AEROBIC FERMENTATION USING ASPERGILLUS TERREUS AND LOW COST CARBOHYDRATES FROM BEET OR CANE: KANE ET AL、US PATENT 2、385、283 (1945 TO PFIZER).、SYNTHESIS FROM PROPARGYL CHLORIDE、CARBON MONOXIDE、NICKEL CARBONYL & WATER: CHIUSOLI、US PATENT 3、025、320 (1962 TO MONTECATINI).、U.S. Production: 2023: 2、500、000 - <4、000、000 lb、2022: 7、000 - <8、2021: 8、000 - <10、2020: 5、000 - <7、General Manufacturing Information: Petrochemical Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Plastics Product Manufacturing、Pesticide、Fertilizer、and Other Agricultural Chemical Manufacturing、Butanedioic acid、2-methylene-: ACTIVE |
登记用途：Uses: Used in copolymerization and to make resins、plasticizers、and lube oil additives、[HSDB] Used as a comonomer in the production of acrylic fibers and latex、[eChemPortal: SIDSUNEP]、COPOLYMERIZATIONS、RESINS、PLASTICIZERS、LUBE OIL ADDITIVES、INTERMEDIATE、Industry Uses: Surface modifier、Intermediate、Not Known or Reasonably Ascertainable、Monomers、Consumer Uses: Not Known or Reasonably Ascertainable、Household Products: Information on 1 consumer products that contain Methylenesuccinic acid in the following categories is provided:、• Auto Products、Methods of Manufacturing: OBTAINED BY DRY DISTILLATION OF CITRIC ACID AND SUBSEQUENT TREATMENT OF THE ANHYDRIDE WITH WATER. PRODUCED ON A LARGE SCALE BY SUBMERGED AEROBIC FERMENTATION USING ASPERGILLUS TERREUS AND LOW COST CARBOHYDRATES FROM BEET OR CANE: KANE ET AL、US PATENT 2、385、283 (1945 TO PFIZER).、SYNTHESIS FROM PROPARGYL CHLORIDE、CARBON MONOXIDE、NICKEL CARBONYL & WATER: CHIUSOLI、US PATENT 3、025、320 (1962 TO MONTECATINI).、U.S. Production: 2023: 2、500、000 - <4、000、000 lb、2022: 7、000 - <8、2021: 8、000 - <10、2020: 5、000 - <7、General Manufacturing Information: Petrochemical Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Plastics Product Manufacturing、Pesticide、Fertilizer、and Other Agricultural Chemical Manufacturing、Butanedioic acid、2-methylene-: ACTIVE。
衣康酸 是一种化工化合物，登记 CAS 号为 97-65-4，分子式 C5H6O4（分子量 130.10）。
登记 CAS 号：97-65-4
其分子式 C5H6O4 由 5 个碳、6 个氢、4 个氧 组成。
别名/同义词：衣康酸 · Itaconic Acid
衣康酸 的 CAS 登记号为 97-65-4。
分子式 C5H6O4，分子量 130.10。
别名/同义词：衣康酸、Itaconic Acid。
登记用途：Uses: Used in copolymerization and to make resins、plasticizers、and lube oil additives、[HSDB] Used as a comonomer in the production of acrylic fibers and latex、[eChemPortal: SIDSUNEP]、COPOLYMERIZATIONS、RESINS、PLASTICIZERS、LUBE OIL ADDITIVES、INTERMEDIATE、Industry Uses: Surface modifier、Intermediate、Not Known or Reasonably Ascertainable、Monomers、Consumer Uses: Not Known or Reasonably Ascertainable、Household Products: Information on 1 consumer products that contain Methylenesuccinic acid in the following categories is provided:、• Auto Products、Methods of Manufacturing: OBTAINED BY DRY DISTILLATION OF CITRIC ACID AND SUBSEQUENT TREATMENT OF THE ANHYDRIDE WITH WATER. PRODUCED ON A LARGE SCALE BY SUBMERGED AEROBIC FERMENTATION USING ASPERGILLUS TERREUS AND LOW COST CARBOHYDRATES FROM BEET OR CANE: KANE ET AL、US PATENT 2、385、283 (1945 TO PFIZER).、SYNTHESIS FROM PROPARGYL CHLORIDE、CARBON MONOXIDE、NICKEL CARBONYL & WATER: CHIUSOLI、US PATENT 3、025、320 (1962 TO MONTECATINI).、U.S. Production: 2023: 2、500、000 - <4、000、000 lb、2022: 7、000 - <8、2021: 8、000 - <10、2020: 5、000 - <7、General Manufacturing Information: Petrochemical Manufacturing、Adhesive Manufacturing、Paint and Coating Manufacturing、Plastics Product Manufacturing、Pesticide、Fertilizer、and Other Agricultural Chemical Manufacturing、Butanedioic acid、2-methylene-: ACTIVE。
衣康酸（CAS 97-65-4）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 97-65-4 |
|---|---|
| PubChem CID | 811 |
| Molecular formula | C5H6O4 |
| IUPAC name | 2-methylidenebutanedioic acid |
| UNII (FDA) | Q4516562YH |
| Molecular Weight | 130.10 |
|---|---|
| XLogP3 | -0.1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 130.02660867 |
| Monoisotopic Mass | 130.02660867 |
| Topological Polar Surface Area | 74.6 |
| Heavy Atom Count | 9 |
| Boiling Point | 268 °C, SUBLIMES |
|---|---|
| Melting Point | 175 °C |
| Solubility | 76.8 mg/mL at 20 °C |
| Density | 1.632 |
| Collision Cross Section | 131.9 Ų [M+Na]+ |
| Collision Cross Section | 119.1 Ų [M-H]- |
Itaconic acid; 97-65-4; 2-Methylenesuccinic acid; 2-methylidenebutanedioic acid; METHYLENESUCCINIC ACID; Methylenebutanedioic acid; Propylenedicarboxylic acid; itaconate; Butanedioic acid, methylene-; 2-Propene-1,2-dicarboxylic acid; Succinic acid, methylene-; 2-methylenebutanedioic acid; DTXSID2026608; NSC-3357; Q4516562YH; DTXCID006608
| Regulatory & Food Contact | FDA Cumulative Estimated Daily Intake (CEDI): FCS FDA Inventory of Food Contact Substances Listed in 21 CFR: FCS POLYITACONIC ACID |
|---|---|
| GHS notification summary | 5.9% (33 / 555) |
| GHS notification summary | 5.9% (33 / 555) |
|---|---|
| Reported hazard statements | H315 (14.8%), H318 (77.7%), H319 (14.1%), H335 (16%), H402 |
This chemical does not meet GHS hazard criteria for 5.9% (33 of 555) of reports.
H315 (14.8%): Causes skin irritation [Warning Skin corrosion/irritation]
Itaconic Acid · CAS 97-65-4 · C5H6O4. UNII Q4516562YH. Boiling Point: 268 °C, SUBLIMES; Melting Point: 175 °C; Solubility: 76.8 mg/mL at 20 °C.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Itaconic Acid