丙咪嗪

CAS 50-49-7C19H24N2MW 280.4

丙咪嗪（CAS 50-49-7）：分子式 C19H24N2、分子量 280.4。

产品概览

CAS号	50-49-7
分子式	C19H24N2
分子量	280.4
熔点	174-175
沸点	160
LogP	4.8
应用领域	Uses: MEDICATION、Medication: antidepressant agent、hydrochloride、Use (kg、approx.) in Germany (2009): >250、Use (kg) in USA (2002): 4110、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Consumption (g per capita) in the USA (2002): 0.0146、Calculated removal (%): 84.3、For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older. May also be used to manage panic disorders、with or without agoraphobia、as a second line agent in ADHD、management of eating disorders、for short-term management of acute depressive episodes in bipolar disorder and schizophrenia、and for symptomatic treatment of postherpetic neuralgia.、Use Classification: Pharmaceuticals、Methods of Manufacturing: HAEFLIGER、SCHINDLER、US PATENT 2、554、736 (1951 TO GEIGY)、HAEFLIGER、SCHINDLER HELV CHIM ACTA 37、472 (1954).、Formulations、Preparations: INJECTION: 25 MG、2 ML、TABLETS: 10、25、& 50 MG.、HYDROCHLORIDE

应用领域

登记用途：Uses: MEDICATION、Medication: antidepressant agent、hydrochloride、Use (kg、approx.) in Germany (2009): >250、Use (kg) in USA (2002): 4110、Consumption (g per capita、approx.) in Germany (2009): 0.00305、Consumption (g per capita) in the USA (2002): 0.0146、Calculated removal (%): 84.3、For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older. May also be used to manage panic disorders、with or without agoraphobia、as a second line agent in ADHD、management of eating disorders、for short-term management of acute depressive episodes in bipolar disorder and schizophrenia、and for symptomatic treatment of postherpetic neuralgia.、Use Classification: Pharmaceuticals、Methods of Manufacturing: HAEFLIGER、SCHINDLER、US PATENT 2、554、736 (1951 TO GEIGY)、HAEFLIGER、SCHINDLER HELV CHIM ACTA 37、472 (1954).、Formulations、Preparations: INJECTION: 25 MG、2 ML、TABLETS: 10、25、& 50 MG.、HYDROCHLORIDE。

技术档案

这个产品是什么

丙咪嗪是一种化工化合物，登记 CAS 号为 50-49-7，分子式 C19H24N2（分子量 280.4）。

识别信息

登记 CAS 号：50-49-7

其分子式 C19H24N2 由 19 个碳、24 个氢、2 个氮组成。

别名/同义词：丙咪嗪 · imipramine

常见问题

丙咪嗪的 CAS 号是多少？

丙咪嗪的 CAS 登记号为 50-49-7。

丙咪嗪的分子式与分子量是多少？

分子式 C19H24N2，分子量 280.4。

丙咪嗪还有哪些别名？

别名/同义词：丙咪嗪、imipramine。

丙咪嗪的登记用途是什么？

PubChem 公开数据

丙咪嗪（CAS 50-49-7）的独立参考数据，整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number	50-49-7
PubChem CID	3696
Molecular formula	C19H24N2
IUPAC name	3-(5,6-dihydrobenzo[b][1]benzazepin-11-yl)-N,N-dimethylpropan-1-amine
UNII (FDA)	OGG85SX4E4

计算分子描述符

Molecular Weight	280.4
XLogP3	4.8
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	2
Rotatable Bond Count	4
Exact Mass	280.193948774
Monoisotopic Mass	280.193948774
Topological Polar Surface Area	6.5
Heavy Atom Count	21

在册的理化数值

Boiling Point	160
Boiling Point	160 °C @ 0.1 MM HG
Melting Point	174-175
Melting Point	174.5 °C
Solubility	18.2
Solubility	In water, 18.2 mg/l @ 24 °C.
Solubility	18.2 mg/L at 24 °C
LogP	4.8
LogP	log Kow = 4.80
LogP	4.80

在册的记载用途

同义词与商品名

imipramine; 50-49-7; Melipramine; Antideprin; Berkomine; Imidobenzyle; Dimipressin; Melipramin; Dynaprin; Intalpram; Nelipramin; Timolet; Irmin; Dpid; Dyna-zina; Impramine

已收录的法规名录

GHS notification summary	75% (6 / 8)

GHS 危害分类

GHS notification summary	75% (6 / 8)
Reported hazard statements	H302 (12.5%), H400 (12.5%)

This chemical does not meet GHS hazard criteria for 75% (6 of 8) of all reports.

H302 (12.5%): Harmful if swallowed [Warning Acute toxicity, oral]

公开数据库对它的描述

imipramine · CAS 50-49-7 · C19H24N2. UNII OGG85SX4E4. Boiling Point: 160; Boiling Point: 160 °C @ 0.1 MM HG; Melting Point: 174-175.

物理形态与操作说明

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。

丙咪嗪