Imidazole (CAS 288-32-4) — formula C3H4N2, molecular weight 68.04 g/mol.
| CAS Number | 288-32-4 |
|---|---|
| Molecular Formula | C3H4N2 |
| Molecular Weight | 68.04 g/mol |
| Melting Point | 90.5 |
| Boiling Point | 257 |
| LogP | -0.1 |
| Applications | Uses: Used as an intermediate (pharmaceuticals, pesticides, dye intermediates, auxiliaries for textile dyeing and finishing, photographic chemicals, and corrosion inhibitors) and hardener for epoxy resins, Also used in process regulators, anti-freeze agents, photographic applications, laboratory applications, glues, adhesives, cement fillers or sealing compounds, paints, varnishes, lacquers, consumer cleaning and washing agents, swimming pool applications, and in publishing, printing, and reproduction of recorded media, [OECD SIDS], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Painting (Pigments, Binders, and Biocides) [Category: Paint], Plastic Composites Manufacturing [Category: Industry], Photographic Processing [Category: Other], Karl Fischer reagent in analytical chemistry. Reagent in synthetic organic chemistry., ... the bulk of imidazole produced is used in the preparation of biologically active compounds., Biological control of pests, especially fabric-feeding insects, often in combination with dl-p-fluorophenylalanine, an amino-acid inhibitor, also as a contact insecticide in an oil spray., In the chemical industry as an intermediate in the production of pharmaceuticals, photographic chemicals and corrosion inhibitors., Used in cosmetics as a buffering agent, Use Classification: Cosmetics -> Buffering, Environmental transformation -> Pesticide transformation products (metabolite, successor), Industry Uses: Intermediate, Methods of Manufacturing: In the generally applicable Radziszewski reaction, a 1, 2-dicarbonyl compound is condensed with an aldehyde and ammonia ... in a molar ratio of 1:1: 2, respectively. Replacement of a molar equivalent of ammonia with a primary amine ... leads to the corresponding 1-substituted imidazoles. ... The reaction is usually carried out in water or a water-alcohol mixture at 50-100 °C. Work-up may involve the usual processes (e.g., distillation, extraction, and crystallization). Distillation leads to imidazole with a purity > 99%. The yield is generally 60-85%., Prepared by the action of ammonia on glyoxal, ... from glyoxal, ammonia, and formaldehyde, ... vapor phase synthesis from formamide and ethylenediamine in the presence of a dehydrogenation catalyst., U.S. Production: 2023: 50, 000 - <250, 000 lb, 2022: 50, 2021: 50, 2020: 50, Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Imidazole:, Table: National Aggregate Production Volume (pounds) [Table#8542], General Manufacturing Information: All Other Basic Organic Chemical Manufacturing, 1H-Imidazole: ACTIVE |
Documented applications: Uses: Used as an intermediate (pharmaceuticals, pesticides, dye intermediates, auxiliaries for textile dyeing and finishing, photographic chemicals, and corrosion inhibitors) and hardener for epoxy resins, Also used in process regulators, anti-freeze agents, photographic applications, laboratory applications, glues, adhesives, cement fillers or sealing compounds, paints, varnishes, lacquers, consumer cleaning and washing agents, swimming pool applications, and in publishing, printing, and reproduction of recorded media, [OECD SIDS], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Painting (Pigments, Binders, and Biocides) [Category: Paint], Plastic Composites Manufacturing [Category: Industry], Photographic Processing [Category: Other], Karl Fischer reagent in analytical chemistry. Reagent in synthetic organic chemistry., ... the bulk of imidazole produced is used in the preparation of biologically active compounds., Biological control of pests, especially fabric-feeding insects, often in combination with dl-p-fluorophenylalanine, an amino-acid inhibitor, also as a contact insecticide in an oil spray., In the chemical industry as an intermediate in the production of pharmaceuticals, photographic chemicals and corrosion inhibitors., Used in cosmetics as a buffering agent, Use Classification: Cosmetics -> Buffering, Environmental transformation -> Pesticide transformation products (metabolite, successor), Industry Uses: Intermediate, Methods of Manufacturing: In the generally applicable Radziszewski reaction, a 1, 2-dicarbonyl compound is condensed with an aldehyde and ammonia ... in a molar ratio of 1:1: 2, respectively. Replacement of a molar equivalent of ammonia with a primary amine ... leads to the corresponding 1-substituted imidazoles. ... The reaction is usually carried out in water or a water-alcohol mixture at 50-100 °C. Work-up may involve the usual processes (e.g., distillation, extraction, and crystallization). Distillation leads to imidazole with a purity > 99%. The yield is generally 60-85%., Prepared by the action of ammonia on glyoxal, ... from glyoxal, ammonia, and formaldehyde, ... vapor phase synthesis from formamide and ethylenediamine in the presence of a dehydrogenation catalyst., U.S. Production: 2023: 50, 000 - <250, 000 lb, 2022: 50, 2021: 50, 2020: 50, Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Imidazole:, Table: National Aggregate Production Volume (pounds) [Table#8542], General Manufacturing Information: All Other Basic Organic Chemical Manufacturing, 1H-Imidazole: ACTIVE.
Imidazole is a chemical compound with CAS registry number 288-32-4 and molecular formula C3H4N2 (molecular weight 68.04 g/mol).
CAS number: 288-32-4
Its molecular formula C3H4N2 comprises 3 C, 4 H, 2 N atoms.
Also known as: Imidazole · 咪唑
The CAS registry number of Imidazole is 288-32-4.
Molecular formula C3H4N2, molecular weight 68.04 g/mol.
It is also registered under: Imidazole, 咪唑.
Recorded applications: Uses: Used as an intermediate (pharmaceuticals, pesticides, dye intermediates, auxiliaries for textile dyeing and finishing, photographic chemicals, and corrosion inhibitors) and hardener for epoxy resins, Also used in process regulators, anti-freeze agents, photographic applications, laboratory applications, glues, adhesives, cement fillers or sealing compounds, paints, varnishes, lacquers, consumer cleaning and washing agents, swimming pool applications, and in publishing, printing, and reproduction of recorded media, [OECD SIDS], Textiles (Fiber & Fabric Manufacturing) [Category: Industry], Painting (Pigments, Binders, and Biocides) [Category: Paint], Plastic Composites Manufacturing [Category: Industry], Photographic Processing [Category: Other], Karl Fischer reagent in analytical chemistry. Reagent in synthetic organic chemistry., ... the bulk of imidazole produced is used in the preparation of biologically active compounds., Biological control of pests, especially fabric-feeding insects, often in combination with dl-p-fluorophenylalanine, an amino-acid inhibitor, also as a contact insecticide in an oil spray., In the chemical industry as an intermediate in the production of pharmaceuticals, photographic chemicals and corrosion inhibitors., Used in cosmetics as a buffering agent, Use Classification: Cosmetics -> Buffering, Environmental transformation -> Pesticide transformation products (metabolite, successor), Industry Uses: Intermediate, Methods of Manufacturing: In the generally applicable Radziszewski reaction, a 1, 2-dicarbonyl compound is condensed with an aldehyde and ammonia ... in a molar ratio of 1:1: 2, respectively. Replacement of a molar equivalent of ammonia with a primary amine ... leads to the corresponding 1-substituted imidazoles. ... The reaction is usually carried out in water or a water-alcohol mixture at 50-100 °C. Work-up may involve the usual processes (e.g., distillation, extraction, and crystallization). Distillation leads to imidazole with a purity > 99%. The yield is generally 60-85%., Prepared by the action of ammonia on glyoxal, ... from glyoxal, ammonia, and formaldehyde, ... vapor phase synthesis from formamide and ethylenediamine in the presence of a dehydrogenation catalyst., U.S. Production: 2023: 50, 000 - <250, 000 lb, 2022: 50, 2021: 50, 2020: 50, Non-confidential 2016 Chemical Data Reporting (CDR) information on the production and use of chemicals manufactured or imported into the United States. Chemical: Imidazole:, Table: National Aggregate Production Volume (pounds) [Table#8542], General Manufacturing Information: All Other Basic Organic Chemical Manufacturing, 1H-Imidazole: ACTIVE.
Independent reference data for Imidazole (CAS 288-32-4), compiled from public chemistry databases.
| CAS 号 | 288-32-4 |
|---|---|
| PubChem CID | 795 |
| 分子式 | C3H4N2 |
| 分子量 | 68.04 g/mol |
| IUPAC 名称 | 1H-imidazole |
| InChIKey | RAXXELZNTBOGNW-UHFFFAOYSA-N |
| UNII（FDA） | 7GBN705NH1 |
| ChEBI 编号 | CHEBI:16069 |
| Molecular Weight | 68.08 |
|---|---|
| XLogP3 | -0.1 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 1 |
| Rotatable Bond Count | 0 |
| Exact Mass | 68.037448136 |
| Monoisotopic Mass | 68.037448136 |
| Topological Polar Surface Area | 28.7 |
| Heavy Atom Count | 5 |
| Boiling Point | 257 |
|---|---|
| Boiling Point | 257 °C |
| Boiling Point | 268 °C |
| Boiling Point | 257 °C @760 [mm Hg] |
| Melting Point | 90.5 |
| Melting Point | 89.52 °C |
| Melting Point | 90.5 °C |
| Melting Point | 89 °C |
| Flash Point | 145 °C (293 °F) - closed cup |
| Flash Point | 145 °C c.c. |
imidazole; 1H-Imidazole; 288-32-4; Glyoxaline; Imidazol; Iminazole; Miazole; 1,3-Diazole; Imutex; Glyoxalin; 1,3-Diaza-2,4-cyclopentadiene; Pyrro(b)monazole; Glioksal; Formamidine, N,N'-vinylene-; Pyrro[b]monazole; Methanimidamide, N,N'-1,2-ethenediyl-
| GHS 通报统计 | 0.2% (2 / 945) |
|---|
| GHS 通报统计 | 0.2% (2 / 945) |
|---|---|
| 已通报的危害声明 | H302, H314, H318 (47.3%), H360 (56.1%), H361 (28.6%), H319, H371 |
咪唑 的 CAS 号为 288-32-4，分子式 C3H4N2，分子量 68.04 g/mol。 UNII 7GBN705NH1; ChEBI 16069; InChIKey RAXXELZNTBOGNW-UHFFFAOYSA-N. Boiling Point: 257; Boiling Point: 257 °C; Boiling Point: 268 °C.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 咪唑