Imazethapyr

Description

Imazethapyr · CAS 81335-77-5 · C15H19N3O3. UNII 72T2IN94I4. Boiling Point: 180 °C (decomposes); Melting Point: 173 °C; Solubility: In water, 1415 ppm at 25 °C.

Identification

CAS Registry Number	81335-77-5
PubChem CID	54740
Molecular formula	C15H19N3O3
IUPAC name	5-ethyl-2-(4-methyl-5-oxo-4-propan-2-yl-1H-imidazol-2-yl)pyridine-3-carboxylic acid
UNII (FDA)	72T2IN94I4

Computed Descriptors

Molecular Weight	289.33
XLogP3	2
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	4
Exact Mass	289.14264148
Monoisotopic Mass	289.14264148
Topological Polar Surface Area	91.7
Heavy Atom Count	21
Formal Charge	0

Physical & Chemical Properties

Boiling Point	180 °C (decomposes)
Melting Point	173 °C
Solubility	In water, 1415 ppm at 25 °C
Density	1.10 to 1.12 at 21 °C
LogP	1.09
Dissociation Constants	pK1 = 2.1; pK2 = 3.9

Physical description & handling notes

• White to off-white solid; [Merck Index] Colorless solid; [HSDB]
• White to off-white crystalline solid
• Off-white to tan solid
• In acetone 48.2, methanol 105, tolulene 5, dichloromethane 185, isopropanol 17, heptane 0.9 (all in g/L, 25 °C)
• log Kow = 1.49 (pH 7); 1.04 (pH 5): 1.20 (pH 9), all at 25 °C
• Rapidly degraded in sunlight, DT50 about 2.1 days (pH 7, 22-24 °C)

Regulatory Status

GHS notification summary	2.2% (3 / 135)

GHS Hazard Classification

GHS notification summary	2.2% (3 / 135)
Reported hazard statements	H312 (20.7%), H400 (97.8%), H410 (97.8%)

Documented Uses

• Selective imidazolinone herbicide; [Merck Index] Used to control annual and perennial grasses and broad-leaved weeds in soy beans; [HSDB]
• Control of many major annual and perennial grass and broad leaved weeds in most major crops ... Applied pre-plant incorporated, pre-emergence, or post-emergence.
• Imazethapyr is produced by reaction of 2,3- dicarboxymethyl-5-ethylpyridine with 2-aminoamide- 3-methylbutane in the presence of two equivalents of tert-butoxide.
• In rats, following oral administration, 92% was excreted in the urine and 5% in the feces within 24 hr. Residue levels in blood, liver, kidney, muscle, and fat tissues were <0.01 ppm after 48 hr.
• Rapidly metabolized in non-susceptible plants (50% loss in soyabeans in 1.6 days).
• Absorbed by plant roots and foliage, being translocated to meristematic regions where it inhibits the biosynthesis of valine, leucine and isoleucine preventing cell division.

Synonyms

IMAZETHAPYR; 81335-77-5; Pursuit; Pivot; DTXSID3024287; FABIAN; CL 263499; 72T2IN94I4; AC 263,499; AC-263499; DTXCID004287; 3-Pyridinecarboxylic acid, 2-[4,5-dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl]-5-ethyl-; (RS)-5-Ethyl-2(4-isopropyl-4-methyl-5-oxo-2-imidazolin-2-yl)nicotinic acid; (+-)-2-(4,5-Dihydro-4-methyl-4(1-methylethyl)-5-oxo-1H-imidazol-2yl)-5-ethyl-3-pyridinecarboxylic acid; 2-(4,5-Dihydro-4-methyl-4-(1-methylethyl)-5-oxo-1H-imidazol-2-yl)-5-ethyl-3-pyridinecarboxylic acid; CL-263499

Frequently Asked Questions

What are the CAS number and molecular formula of Imazethapyr?

CAS 81335-77-5; molecular formula C15H19N3O3; molecular weight — g/mol.

What other names is Imazethapyr known by?

IMAZETHAPYR, 81335-77-5, Pursuit, Pivot, DTXSID3024287, FABIAN.

Is Imazethapyr classified as hazardous?

2.2% of GHS notifications report no hazard classification (3 of 135).

What are the key physical properties of Imazethapyr?

Boiling Point: 180 °C (decomposes); Melting Point: 173 °C; Solubility: In water, 1415 ppm at 25 °C; Density: 1.10 to 1.12 at 21 °C.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.