富马酸伊布利特

富马酸伊布利特（CAS 122647-32-9）的独立参考数据，整理自公开化学数据库。

各数据库的登记标识

计算分子描述符

在册的理化数值

在册的记载用途

The synthesis starts with a Friedel-Crafts acylation of methanesulfonanilide with succinic anhydride in presence of AlCl3 yielding 4-[(methylsulfonyl)amino]-gamma-oxobenzenebutanoic acid, which is treated with N-ethylheptylamine and dicyclohexylcarbodiimide (DCC) in DMF to give the corresponding amide. Reduction with LiAlH4 in THF in the last step provides the desired drug substance.Indicated for the rapid conversion of atrial fibrillation or atrial flutter of recent onset to sinus rhythm.

同义词与商品名

Ibutilide; 122647-31-8; Ibutilida; Ibutilidum; n-(4-{4-[ethyl(heptyl)amino]-1-hydroxybutyl}phenyl)methanesulfonamide; N-(4-(4-(ethyl(heptyl)amino)-1-hydroxybutyl)phenyl)methanesulfonamide; N-[4-[4-[ethyl(heptyl)amino]-1-hydroxybutyl]phenyl]methanesulfonamide; 2436VX1U9B; DTXSID20861271; N-[4-[4-(ethylheptylamino)-1-hydroxybutyl]phenyl]methanesulfonamide; N-(4-(4-(ethylheptylamino)-1-hydroxybutyl)phenyl)methanesulfonamide; RefChem:56518; C01BD05; DTXCID30197270; Ibutilidum [INN-Latin]; Ibutilida [INN-Spanish]

公开数据库对它的描述

Ibutilide fumarate · CAS 122647-32-9 · C20H36N2O3S. UNII 2436VX1U9B. Solubility: 100; Solubility: 4.73e-03 g/L; LogP: 4.6.

物理形态与操作说明

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。