Hydroxypropyl Methylcellulose Phthalate（CAS 99011-02-6）：分子式 C14H16N4、分子量 240.30；类别 医药中间体及原料药。
| CAS号 | 99011-02-6 |
|---|---|
| 分子式 | C14H16N4 |
| 分子量 | 240.30 |
| 熔点 | 292-294 °C |
| LogP | 2.7 |
| 应用领域 | Uses: MEDICATION、Adjuvants、Immunologic、Antineoplastic Agents、Use (kg、approx.) in Germany (2009): >10、Use (kg) in USA (2002): 680、Consumption (g per capita、approx.) in Germany (2009): 0.000122、Consumption (g per capita) in the USA (2002): 0.00241、Calculated removal (%): 31.5、Methods of Manufacturing: Preparation: J. F. Gerster、European Patent Office 145340、idem、United States of America 4689338 (1985、1987 both to Riker)、Formulations、Preparations: For topical use、imiquimod is commercially、available、as a 5% cream. Each gram of the cream contains 50 mg of imiquimod in an off-white、oil-in-water vanishing cream base. Imiquimod topical cream contains methylparaben and propylparaben as preservatives.、Topical: Cream 5%、Aldara (Graceway).、Zyclara、Beselna、General Manufacturing Information: Cellulose、hydrogen 1、2-benzenedicarboxylate、2-hydroxypropyl methyl ether: ACTIVE |
| 类别 | Pharma Excipients |
登记用途：Uses: MEDICATION、Adjuvants、Immunologic、Antineoplastic Agents、Use (kg、approx.) in Germany (2009): >10、Use (kg) in USA (2002): 680、Consumption (g per capita、approx.) in Germany (2009): 0.000122、Consumption (g per capita) in the USA (2002): 0.00241、Calculated removal (%): 31.5、Methods of Manufacturing: Preparation: J. F. Gerster、European Patent Office 145340、idem、United States of America 4689338 (1985、1987 both to Riker)、Formulations、Preparations: For topical use、imiquimod is commercially、available、as a 5% cream. Each gram of the cream contains 50 mg of imiquimod in an off-white、oil-in-water vanishing cream base. Imiquimod topical cream contains methylparaben and propylparaben as preservatives.、Topical: Cream 5%、Aldara (Graceway).、Zyclara、Beselna、General Manufacturing Information: Cellulose、hydrogen 1、2-benzenedicarboxylate、2-hydroxypropyl methyl ether: ACTIVE。
Hydroxypropyl Methylcellulose Phthalate 是一种医药中间体或原料药类化合物，登记 CAS 号为 99011-02-6，分子式 C14H16N4（分子量 240.30），归属于医药中间体及原料药大类化工原料。
登记 CAS 号：99011-02-6
其分子式 C14H16N4 由 14 个碳、16 个氢、4 个氮 组成。
别名/同义词：Hydroxypropyl Methylcellulose Phthalate · Hypromellose · Imiquimod
所属分类：医药中间体及原料药
Hydroxypropyl Methylcellulose Phthalate 的 CAS 登记号为 99011-02-6。
分子式 C14H16N4，分子量 240.30。
别名/同义词：Hydroxypropyl Methylcellulose Phthalate、Hypromellose、Imiquimod。
登记用途：Uses: MEDICATION、Adjuvants、Immunologic、Antineoplastic Agents、Use (kg、approx.) in Germany (2009): >10、Use (kg) in USA (2002): 680、Consumption (g per capita、approx.) in Germany (2009): 0.000122、Consumption (g per capita) in the USA (2002): 0.00241、Calculated removal (%): 31.5、Methods of Manufacturing: Preparation: J. F. Gerster、European Patent Office 145340、idem、United States of America 4689338 (1985、1987 both to Riker)、Formulations、Preparations: For topical use、imiquimod is commercially、available、as a 5% cream. Each gram of the cream contains 50 mg of imiquimod in an off-white、oil-in-water vanishing cream base. Imiquimod topical cream contains methylparaben and propylparaben as preservatives.、Topical: Cream 5%、Aldara (Graceway).、Zyclara、Beselna、General Manufacturing Information: Cellulose、hydrogen 1、2-benzenedicarboxylate、2-hydroxypropyl methyl ether: ACTIVE。
所属分类：Pharma Excipients。
Hydroxypropyl Methylcellulose Phthalate（CAS 99011-02-6）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 99011-02-6 |
|---|---|
| PubChem CID | 57469 |
| Molecular formula | C14H16N4 |
| IUPAC name | 1-(2-methylpropyl)imidazo[4,5-c]quinolin-4-amine |
| UNII (FDA) | P1QW714R7M |
| Molecular Weight | 240.30 |
|---|---|
| XLogP3 | 2.6 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 3 |
| Rotatable Bond Count | 2 |
| Exact Mass | 240.137496527 |
| Monoisotopic Mass | 240.137496527 |
| Topological Polar Surface Area | 56.7 |
| Heavy Atom Count | 18 |
| Melting Point | 292-294 °C |
|---|---|
| Melting Point | 292 - 294 °C |
| Solubility | 2.47e-01 g/L |
| LogP | 2.7 |
| LogP | 2.89 |
IMIQUIMOD; 99011-02-6; Aldara; 1-(2-methylpropyl)-1H-imidazo[4,5-c]quinolin-4-amine; Zyclara; 1-isobutyl-1H-imidazo[4,5-c]quinolin-4-amine; 4-Amino-1-isobutyl-1H-imidazo[4,5-c]quinoline; R-837; R 837; 4-Amino-1-isobutyl-1H-imidazo(4,5-c)quinoline; S-26308; DTXSID7041047; TMX-101; S 26308; Imiquimodum; S26308
| GHS notification summary | 2.1% (1 / 47) |
|---|
| GHS notification summary | 2.1% (1 / 47) |
|---|---|
| Reported hazard statements | H300 (83%), H315 (93.6%), H319 (91.5%), H335 (87.2%), H413 (50%) |
This chemical does not meet GHS hazard criteria for 2.1% (1 of 47) of reports.
H300 (83%): Fatal if swallowed [Danger Acute toxicity, oral]
Imiquimod · CAS 99011-02-6 · C14H16N4. UNII P1QW714R7M. Melting Point: 292-294 °C; Melting Point: 292 - 294 °C; Solubility: 2.47e-01 g/L.
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Hydroxypropyl Methylcellulose Phthalate