十六烷基磷酸胆碱

十六烷基磷酸胆碱（CAS 58066-85-6）的独立参考数据，整理自公开化学数据库。

各数据库的登记标识

计算分子描述符

在册的理化数值

在册的记载用途

For the treatment of mucosal (caused by Leishmania braziliensis), cutaneous (caused by L. braziliensis, L. guyanensis, and L. panamensis), and visceral leishmaniasis (caused by L. donovani). In comparing Leishmania drug susceptibility, it has been found that L. donovani is the most susceptible to miltefosine while L. major is the least susceptible. Off-label use includes treatment of free-living amebae (FLA) infections (unlabeled use; CDC, 2013).Miltefosine is an orally available, alkyl phospholipid that is used in the treatment of both cutaneous and visceral leishmaniasis. Miltefosine therapy is often accompanied by transient mild-to-moderate serum aminotransferase elevations during the first 1 or 2 weeks of treatment, but has not been implicated in cases of clinically apparent liver injury with jaundice.

同义词与商品名

Miltefosine; 58066-85-6; Hexadecylphosphocholine; Impavido; Miltex; HDPC; Hexadecylphosphorylcholine; Miltefosina; Miltefosinum; n-Hexadecylphosphorylcholine; hexadecyl 2-(trimethylazaniumyl)ethyl phosphate; D-18506; miltefosin; 53EY29W7EC; NSC-605583; DTXSID7045942

GHS 危害分类

Reported hazard statements	H301 (100%), H319 (11.4%), H334 (84.8%), H361 (12.7%), H372 (11.4%)

H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]

H319 (11.4%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]

公开数据库对它的描述

hexadecylphosphocholine · CAS 58066-85-6 · C21H46NO4P. UNII 53EY29W7EC. Dissociation Constants: ~2.

物理形态与操作说明

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。