Gentamycin

Description

Gentamycin · CAS 1403-66-3 · C21H43N5O7. UNII GENTAMYCIN. Melting Point: 105; Melting Point: 102-108 °C; Melting Point: 105 °C (decomposition).

Identification

CAS Registry Number	1403-66-3
PubChem CID	3467
Molecular formula	C21H43N5O7
IUPAC name	2-[4,6-diamino-3-[3-amino-6-[1-(methylamino)ethyl]oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol
UNII (FDA)	GENTAMYCIN

Computed Descriptors

Molecular Weight	477.6
XLogP3	-4.1
Hydrogen Bond Donor Count	8
Hydrogen Bond Acceptor Count	12
Rotatable Bond Count	7
Exact Mass	477.31624873
Monoisotopic Mass	477.31624873
Topological Polar Surface Area	200
Heavy Atom Count	33
Formal Charge	0

Physical & Chemical Properties

Melting Point	105
Melting Point	102-108 °C
Melting Point	105 °C (decomposition)
Solubility	1.26e+01 g/L
LogP	-3.1

Physical description & handling notes

• Solid
• White amorphous powder
• Freely soluble in water
• Soluble in pyridine, dimethylformamide, in acidic media with salt formation; moderately soluble in methanol, ethanol, acetone; practically insoluble in benzene, halogenated hydrocarbons
• Stable in light, air, and heat /Gentamycin sulfate/
• Specific optical rotation: +146 deg at 25 °C/D

Regulatory Status

Regulatory & Food Contact	ANTIMICROBIAL_AGENT: Veterinary Drug BIGENTAL JECFA ADI: 0-0.02 mg/kg bw TRS 888-JECFA 50/22 FAS 41-JECFA 50/29 UTEROGEN

GHS Hazard Classification

Reported hazard statements	H317 (47.6%), H334 (46.6%), H360 (35.9%), H372 (52.4%), H400 (52.4%), H410 (52.4%)

Documented Uses

• Anti-Bacterial Agents; Protein Synthesis Inhibitors
• Use (kg; approx.) in Germany (2009): >250
• Use (kg; exact) in Germany (2009): 447
• Consumption (g per capita; approx.) in Germany (2009): 0.00305
• Consumption (g per capita; exact) in Germany (2009): 0.00546
• Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients

Synonyms

gentamicin; Uromycine; Cidomycin; Gentamycinum; 1403-66-3; Gentamicina; Gentamicine; Gentamycin-creme; GENTAMYCIN; Oksitselanim; Lyramycin; Septigen; Gentamycins; T6Z9V48IKG; Garamicin; Gentamycin Complex

Frequently Asked Questions

What are the CAS number and molecular formula of Gentamycin?

CAS 1403-66-3; molecular formula C21H43N5O7; molecular weight — g/mol.

What other names is Gentamycin known by?

gentamicin, Uromycine, Cidomycin, Gentamycinum, 1403-66-3, Gentamicina.

What is the regulatory status of Gentamycin?

Documented regulatory listings: ANTIMICROBIAL_AGENT: Veterinary Drug; BIGENTAL; JECFA ADI: 0-0.02 mg/kg bw.

Is Gentamycin classified as hazardous?

Hazard statements reported: H317, H334, H360, H372, H400.

What are the key physical properties of Gentamycin?

Melting Point: 105; Melting Point: 102-108 °C; Melting Point: 105 °C (decomposition); Solubility: 1.26e+01 g/L.

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.