framycetin sulphate (CAS 4146-30-9) — formula C23H46N6O13, molecular weight 614.6; category inorganic chemicals.
| CAS Number | 4146-30-9 |
|---|---|
| Molecular Formula | C23H46N6O13 |
| Molecular Weight | 614.6 |
| Melting Point | 6 °C (sulfate form) |
| LogP | -7.8 |
| Applications | Uses: For neomycin (USEPA, OPP Pesticide Code: 006303) there are 0 labels match., SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., Broad-spectrum antibiotic, ... Used for bladder irrigation ... to prevent bacteriuria and bacteremia associated with the use of indwelling catheters., Veterinary bactericidal drug, For more Uses (Complete) data for Neomycin (7 total), please visit the HSDB record page., Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 92.1, Topical uses include treatment for superficial eye infections caused by susceptible bacteria (used in combination with other antiinfectives), treatment of otitis externa caused by susceptible bacteria, treatment or prevention of bacterial infections in skin lesions, and use as a continuous short-term irrigant or rinse to prevent bacteriuria and gram negative rod bacteremia in abacteriuric patients with indwelling catheters. May be used orally to treat hepatic encephalopathy, as a perioperative prophylactic agent, and as an adjunct to fluid and electrolyte replacement in the treatment of diarrhea caused to enteropathogenic E. coli (EPEC)., Use Classification: Veterinary Drug -> ANTIMICROBIAL_AGENT -> JECFA Functional Classes, Methods of Manufacturing: Produced by Streptomyces fradiae., Antibiotics can broadly be classified into the following categories: aminoglycosides, beta-lactams, macrolides, and tetracyclines, of which only the tetracylines do not use ion-exchange resins in their recovery from fermentation broths., Ion-exchange resins, Formulations, Preparations: Table: Neomycin Sulfate Preparations [Table#4505], Table: Neomycin Sulfate Combinations Preparations [Table#4506], Bulk: Powder: Neo-Rx Micronized Antibiotic Powder for Prescription Compounding (Pharma-Tek)., Neomycin sulfate, Urogenital: For irrigation, concentrate, sterile: 57 mg Neosporin Sulfate (40 mg of neomycin) per mL and Polymyxin B Sulfate 200, 000 units (of polymyxin B) per mL, Neosporin G.U. Irrigant (Monarch)., For more Formulations, Preparations (Complete) data for Neomycin (12 total), General Manufacturing Information: Antibiotic complex composed of of neomycins A, B, and C., Neomycin is a mixture of neomycin B (119-04-0) ... and neomycin C (66-86-4) ... Neomycin B is the main component. |
| Category | Inorganic Chemicals |
Documented applications: Uses: For neomycin (USEPA, OPP Pesticide Code: 006303) there are 0 labels match., SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., Broad-spectrum antibiotic, ... Used for bladder irrigation ... to prevent bacteriuria and bacteremia associated with the use of indwelling catheters., Veterinary bactericidal drug, For more Uses (Complete) data for Neomycin (7 total), please visit the HSDB record page., Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 92.1, Topical uses include treatment for superficial eye infections caused by susceptible bacteria (used in combination with other antiinfectives), treatment of otitis externa caused by susceptible bacteria, treatment or prevention of bacterial infections in skin lesions, and use as a continuous short-term irrigant or rinse to prevent bacteriuria and gram negative rod bacteremia in abacteriuric patients with indwelling catheters. May be used orally to treat hepatic encephalopathy, as a perioperative prophylactic agent, and as an adjunct to fluid and electrolyte replacement in the treatment of diarrhea caused to enteropathogenic E. coli (EPEC)., Use Classification: Veterinary Drug -> ANTIMICROBIAL_AGENT -> JECFA Functional Classes, Methods of Manufacturing: Produced by Streptomyces fradiae., Antibiotics can broadly be classified into the following categories: aminoglycosides, beta-lactams, macrolides, and tetracyclines, of which only the tetracylines do not use ion-exchange resins in their recovery from fermentation broths., Ion-exchange resins, Formulations, Preparations: Table: Neomycin Sulfate Preparations [Table#4505], Table: Neomycin Sulfate Combinations Preparations [Table#4506], Bulk: Powder: Neo-Rx Micronized Antibiotic Powder for Prescription Compounding (Pharma-Tek)., Neomycin sulfate, Urogenital: For irrigation, concentrate, sterile: 57 mg Neosporin Sulfate (40 mg of neomycin) per mL and Polymyxin B Sulfate 200, 000 units (of polymyxin B) per mL, Neosporin G.U. Irrigant (Monarch)., For more Formulations, Preparations (Complete) data for Neomycin (12 total), General Manufacturing Information: Antibiotic complex composed of of neomycins A, B, and C., Neomycin is a mixture of neomycin B (119-04-0) ... and neomycin C (66-86-4) ... Neomycin B is the main component..
framycetin sulphate is an inorganic compound with CAS registry number 4146-30-9 and molecular formula C23H46N6O13 (molecular weight 614.6), belonging to the inorganic chemicals segment of chemical raw materials.
CAS number: 4146-30-9
Its molecular formula C23H46N6O13 comprises 23 C, 46 H, 6 N, 13 O atoms.
Also known as: framycetin sulphate · 硫酸新霉素
Category: inorganic chemicals
The CAS registry number of framycetin sulphate is 4146-30-9.
Molecular formula C23H46N6O13, molecular weight 614.6.
It is also registered under: framycetin sulphate, 硫酸新霉素.
Recorded applications: Uses: For neomycin (USEPA, OPP Pesticide Code: 006303) there are 0 labels match., SRP: Not registered for current use in the U.S., but approved pesticide uses may change periodically and so federal, state and local authorities must be consulted for currently approved uses., Broad-spectrum antibiotic, ... Used for bladder irrigation ... to prevent bacteriuria and bacteremia associated with the use of indwelling catheters., Veterinary bactericidal drug, For more Uses (Complete) data for Neomycin (7 total), please visit the HSDB record page., Use (kg, approx.) in Germany (2009): >25, Consumption (g per capita, approx.) in Germany (2009): 0.000305, Calculated removal (%): 92.1, Topical uses include treatment for superficial eye infections caused by susceptible bacteria (used in combination with other antiinfectives), treatment of otitis externa caused by susceptible bacteria, treatment or prevention of bacterial infections in skin lesions, and use as a continuous short-term irrigant or rinse to prevent bacteriuria and gram negative rod bacteremia in abacteriuric patients with indwelling catheters. May be used orally to treat hepatic encephalopathy, as a perioperative prophylactic agent, and as an adjunct to fluid and electrolyte replacement in the treatment of diarrhea caused to enteropathogenic E. coli (EPEC)., Use Classification: Veterinary Drug -> ANTIMICROBIAL_AGENT -> JECFA Functional Classes, Methods of Manufacturing: Produced by Streptomyces fradiae., Antibiotics can broadly be classified into the following categories: aminoglycosides, beta-lactams, macrolides, and tetracyclines, of which only the tetracylines do not use ion-exchange resins in their recovery from fermentation broths., Ion-exchange resins, Formulations, Preparations: Table: Neomycin Sulfate Preparations [Table#4505], Table: Neomycin Sulfate Combinations Preparations [Table#4506], Bulk: Powder: Neo-Rx Micronized Antibiotic Powder for Prescription Compounding (Pharma-Tek)., Neomycin sulfate, Urogenital: For irrigation, concentrate, sterile: 57 mg Neosporin Sulfate (40 mg of neomycin) per mL and Polymyxin B Sulfate 200, 000 units (of polymyxin B) per mL, Neosporin G.U. Irrigant (Monarch)., For more Formulations, Preparations (Complete) data for Neomycin (12 total), General Manufacturing Information: Antibiotic complex composed of of neomycins A, B, and C., Neomycin is a mixture of neomycin B (119-04-0) ... and neomycin C (66-86-4) ... Neomycin B is the main component..
Category: Inorganic Chemicals.
Independent reference data for framycetin sulphate (CAS 4146-30-9), compiled from public chemistry databases.
| CAS Registry Number | 4146-30-9 |
|---|---|
| PubChem CID | 8378 |
| Molecular formula | C23H46N6O13 |
| IUPAC name | (2R,3S,4R,5R,6R)-5-amino-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-2-[(2S,3R,4S,5R)-4-[(2R,3R,4R,5S,6S)-3-amino-6-(aminomethyl)-4,5-dihydroxyoxan-2-yl]oxy-3-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-3-hydroxycyclohexyl]oxyoxane-3,4-diol |
| UNII (FDA) | 4BOC774388 |
| Molecular Weight | 614.6 |
|---|---|
| XLogP3 | -9 |
| Hydrogen Bond Donor Count | 13 |
| Hydrogen Bond Acceptor Count | 19 |
| Rotatable Bond Count | 9 |
| Exact Mass | 614.31228554 |
| Monoisotopic Mass | 614.31228554 |
| Topological Polar Surface Area | 353 |
| Heavy Atom Count | 42 |
| Melting Point | 6 °C (sulfate form) |
|---|---|
| Solubility | 6.47e+01 g/L |
| LogP | -7.8 |
| LogP | log Kow = -3.70 |
| Dissociation Constants | pKa = 12.9; pKb = 9.52 (25 °C) |
neomycin; Fradiomycin; Neomas; Nivemycin; Myacyne; Neolate; Caswell No. 595; Vonamycin powder V; Neomin; Neomicina; Neomycine; Neomycinum; 1404-04-2; PIMAVECORT; I16QD7X297; VONAMYCIN
| Regulatory & Food Contact | ANTIMICROBIAL_AGENT: Veterinary Drug 0â60 μg/kg bw TRS 918-JECFA 60/5 FAS 51-JECFA 60/3 |
|---|
| Reported hazard statements | H302 (100%), H317 (100%), H334 (100%), H332 (15.4%), H361 (84.6%), H373 (76.9%) |
|---|
H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
H317 (100%): May cause an allergic skin reaction [Warning Sensitization, Skin]
framycetin sulphate · CAS 4146-30-9 · C23H46N6O13. UNII 4BOC774388. Melting Point: 6 °C (sulfate form); Solubility: 6.47e+01 g/L; LogP: -7.8.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 硫酸新霉素