盐酸氟奋乃静（CAS 146-56-5）：分子式 C22H26F3N3OS、分子量 437.5。
| CAS号 | 146-56-5 |
|---|---|
| 分子式 | C22H26F3N3OS |
| 分子量 | 437.5 |
| 熔点 | 224-226 (Salt) |
| 沸点 | 268-274 °C at 5.00E-01 mm Hg |
| LogP | 4.36 |
| 应用领域 | Uses: A phenothiazine used in the treatment of psychoses、Tranquilizer、THERAPEUTIC CATEGORY: Antipsychotic、MEDICATION、Use (kg、approx.) in Germany (2009): >25、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Calculated removal (%): 48.5、For management of manifestations of psychotic disorders.、Use Classification: Pharmaceuticals、Methods of Manufacturing: Fluphenazine may be prepared by condensing 2-(trifluoromethyl)-10-(3-chloropropyl)phenothiazine with 1-piperazineethanol in toluene with the aid of sodamide. ... The starting phenothiazine compound may be prepared by heating 3-(trifluoromethyl)diphenylamine with sulfur and condensing the resulting 2-(trifluoromethyl)phenothiazine with 1-bromo-3-chloropropane.、Fluphenazine may be prepared by condensing 2-(trifluoromethyl)-10-(3-chloropropyl)phenothiazine with 1-piperazineethanol in toluene with the aid of sodamide. Reaction of the purified base with a double molar quantity of hydrogen chloride yields ...、the hydrochloride salt、. ... The starting phenothiazine compound may be prepared by heating 3-(trifluoromethyl)diphenylamine with sulfur and condensing the resulting 2-(trifluoromethyl)phenothiazine with 1-bromo-3-chloropropane.、Fluphenazine hydrochloride、Fluphenazine is esterified with decanoyl chloride in the presence of pyridine.、Fluphenazine decanoate、Fluphenazine is esterified through reaction with enanthoyl chloride in the presnece of pyridine.、Fluphenazine enanthate、Formulations、Preparations: Fluphenazine Decanoate Preparations: (AHFS、2010):、Table: Fluphenazine Decanoate Preparations: (AHFS、2010): [Table#4536]、Fluphenazine Hydrochloride Preparations: (AHFS、Table: Fluphenazine Hydrochloride Preparations: (AHFS、2010): [Table#4537]、Anatensol、Dapotum、Lyogen、Moditen、Omca、Pacinol、Permitil、Prolixin、Siqualone、Tensofin、Valamina.、Fluphenazine dihydrochloride |
登记用途：Uses: A phenothiazine used in the treatment of psychoses、Tranquilizer、THERAPEUTIC CATEGORY: Antipsychotic、MEDICATION、Use (kg、approx.) in Germany (2009): >25、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Calculated removal (%): 48.5、For management of manifestations of psychotic disorders.、Use Classification: Pharmaceuticals、Methods of Manufacturing: Fluphenazine may be prepared by condensing 2-(trifluoromethyl)-10-(3-chloropropyl)phenothiazine with 1-piperazineethanol in toluene with the aid of sodamide. ... The starting phenothiazine compound may be prepared by heating 3-(trifluoromethyl)diphenylamine with sulfur and condensing the resulting 2-(trifluoromethyl)phenothiazine with 1-bromo-3-chloropropane.、Fluphenazine may be prepared by condensing 2-(trifluoromethyl)-10-(3-chloropropyl)phenothiazine with 1-piperazineethanol in toluene with the aid of sodamide. Reaction of the purified base with a double molar quantity of hydrogen chloride yields ...、the hydrochloride salt、. ... The starting phenothiazine compound may be prepared by heating 3-(trifluoromethyl)diphenylamine with sulfur and condensing the resulting 2-(trifluoromethyl)phenothiazine with 1-bromo-3-chloropropane.、Fluphenazine hydrochloride、Fluphenazine is esterified with decanoyl chloride in the presence of pyridine.、Fluphenazine decanoate、Fluphenazine is esterified through reaction with enanthoyl chloride in the presnece of pyridine.、Fluphenazine enanthate、Formulations、Preparations: Fluphenazine Decanoate Preparations: (AHFS、2010):、Table: Fluphenazine Decanoate Preparations: (AHFS、2010): [Table#4536]、Fluphenazine Hydrochloride Preparations: (AHFS、Table: Fluphenazine Hydrochloride Preparations: (AHFS、2010): [Table#4537]、Anatensol、Dapotum、Lyogen、Moditen、Omca、Pacinol、Permitil、Prolixin、Siqualone、Tensofin、Valamina.、Fluphenazine dihydrochloride。
盐酸氟奋乃静 是一种化工化合物，登记 CAS 号为 146-56-5，分子式 C22H26F3N3OS（分子量 437.5）。
登记 CAS 号：146-56-5
其分子式 C22H26F3N3OS 由 22 个碳、26 个氢、3 个氟、3 个氮、1 个氧、1 个硫 组成。
别名/同义词：盐酸氟奋乃静 · Fluphenazine HCL
盐酸氟奋乃静 的 CAS 登记号为 146-56-5。
分子式 C22H26F3N3OS，分子量 437.5。
别名/同义词：盐酸氟奋乃静、Fluphenazine HCL。
登记用途：Uses: A phenothiazine used in the treatment of psychoses、Tranquilizer、THERAPEUTIC CATEGORY: Antipsychotic、MEDICATION、Use (kg、approx.) in Germany (2009): >25、Consumption (g per capita、approx.) in Germany (2009): 0.000305、Calculated removal (%): 48.5、For management of manifestations of psychotic disorders.、Use Classification: Pharmaceuticals、Methods of Manufacturing: Fluphenazine may be prepared by condensing 2-(trifluoromethyl)-10-(3-chloropropyl)phenothiazine with 1-piperazineethanol in toluene with the aid of sodamide. ... The starting phenothiazine compound may be prepared by heating 3-(trifluoromethyl)diphenylamine with sulfur and condensing the resulting 2-(trifluoromethyl)phenothiazine with 1-bromo-3-chloropropane.、Fluphenazine may be prepared by condensing 2-(trifluoromethyl)-10-(3-chloropropyl)phenothiazine with 1-piperazineethanol in toluene with the aid of sodamide. Reaction of the purified base with a double molar quantity of hydrogen chloride yields ...、the hydrochloride salt、. ... The starting phenothiazine compound may be prepared by heating 3-(trifluoromethyl)diphenylamine with sulfur and condensing the resulting 2-(trifluoromethyl)phenothiazine with 1-bromo-3-chloropropane.、Fluphenazine hydrochloride、Fluphenazine is esterified with decanoyl chloride in the presence of pyridine.、Fluphenazine decanoate、Fluphenazine is esterified through reaction with enanthoyl chloride in the presnece of pyridine.、Fluphenazine enanthate、Formulations、Preparations: Fluphenazine Decanoate Preparations: (AHFS、2010):、Table: Fluphenazine Decanoate Preparations: (AHFS、2010): [Table#4536]、Fluphenazine Hydrochloride Preparations: (AHFS、Table: Fluphenazine Hydrochloride Preparations: (AHFS、2010): [Table#4537]、Anatensol、Dapotum、Lyogen、Moditen、Omca、Pacinol、Permitil、Prolixin、Siqualone、Tensofin、Valamina.、Fluphenazine dihydrochloride。
盐酸氟奋乃静（CAS 146-56-5）的独立参考数据，整理自公开化学数据库。
| CAS Registry Number | 146-56-5 |
|---|---|
| PubChem CID | 3372 |
| Molecular formula | C22H26F3N3OS |
| IUPAC name | 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol |
| UNII (FDA) | S79426A41Z |
| Molecular Weight | 437.5 |
|---|---|
| XLogP3 | 4.4 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 8 |
| Rotatable Bond Count | 6 |
| Exact Mass | 437.17486812 |
| Monoisotopic Mass | 437.17486812 |
| Topological Polar Surface Area | 55.3 |
| Heavy Atom Count | 30 |
| Boiling Point | 268-274 °C at 5.00E-01 mm Hg |
|---|---|
| Boiling Point | BP: 250-252 °C at 0.3 mm Hg; 268-274 °C at 0.5 mm Hg |
| Melting Point | 224-226 (Salt) |
| Melting Point | < 25 °C |
| Solubility | 31.1 |
| Solubility | In water, 31.1 g/L (31.3 mg/L) at 37 °C |
| Solubility | 1.90e-02 g/L |
| LogP | 4.36 |
| LogP | log Kow = 4.36 |
| LogP | 4.2 |
FLUPHENAZINE; 69-23-8; Triflumethazine; Fluorfenazine; Fluorophenazine; Fluorphenazine; Siqualine; Sevinol; Flufenazina; Fluphenazinum; SQ 4918; Flufenazin; 2-[4-[3-[2-(trifluoromethyl)phenothiazin-10-yl]propyl]piperazin-1-yl]ethanol; Moditen; 10-(3-(2-Hydroxyethyl)piperazinopropyl)-2-(trifluoromethyl)phenothiazine; DTXSID2023068
| Reported hazard statements | H301 (100%), H315 (100%), H318 (100%), H330 (100%), H370 (20.8%) |
|---|
H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Fluphenazine HCL · CAS 146-56-5 · C22H26F3N3OS. UNII S79426A41Z. Boiling Point: 268-274 °C at 5.00E-01 mm Hg; Boiling Point: BP: 250-252 °C at 0.3 mm Hg; 268-274 °C at 0.5 mm Hg; Melting Point: 224-226 (Salt).
数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。
English page: Fluphenazine HCL