盐酸氟西汀

CAS 59333-67-4C17H19ClF3NOMW 345.8

盐酸氟西汀（CAS 59333-67-4）：分子式 C17H19ClF3NO、分子量 345.8。

产品概览

CAS号	59333-67-4
分子式	C17H19ClF3NO
分子量	345.8
熔点	158.4-158.9 °C
应用领域	Uses: MEDICATION: Antidepressant、antiobessional、antibulimic、Labeled indication include: major depressive disorder (MDD)、moderate to severe bulimia nervosa、obsessive-compulsive disorder (OCD)、premenstrual dysphoric disorder (PMDD)、panic disorder with or without agoraphobia、and combination treatment with olanzapine for treatment-resistant or bipolar I depression. Unlabeled indications include: selective mutism、mild dementia-associated agitation in nonpsychotic patients、post-traumatic stress disorder (PTSD)、social anxiety disorder、chronic neuropathic pain、fibromyalgia、and Raynaud's phenomenon.、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Formulations、Preparations: Oral: Capsules: 10 mg (of fluoxetine)、Prozac Pulvules (Dista)、Sarafem Pulvules (Lilly)、20 mg (of fluoxetine)、40 mg (of fluoxetine)、Prozac Pulvules (Dista). Capsules、delayed-release (containing enteric-coated pellets): 90 mg (of Fluoxetine) Prozac Weekly (Dista). Solution: 20 mg (of fluoxetine) per 5 ml、Prozac (with alcohol 0.23%) (Dista). Tablets: 10 mg (of fluoxetine) Prozac (scored) (Dista)、Fluoxetine Hydrochloride Tablets (Par).、General Manufacturing Information: Commercially available as the hydrochloride salt.、(S)-Fluoxetine was synthesized from (S)-(-)-3-chloro-1-phenylpropanol by sequential reaction with sodium iodide、methylamine、sodium hydride、and 4-fluorobenzotrifluoride、(S)-Fluoxetine is dextrorotatory (+1.60) in methanol、but is levorotatory (-10.85) in water.、Preparation: ...B. B. Malloy、K. K. Schmiegel、DE 2500110、B. B. Malloy、US 4314081 (1975、1982 both to Lilly)

应用领域

登记用途：Uses: MEDICATION: Antidepressant、antiobessional、antibulimic、Labeled indication include: major depressive disorder (MDD)、moderate to severe bulimia nervosa、obsessive-compulsive disorder (OCD)、premenstrual dysphoric disorder (PMDD)、panic disorder with or without agoraphobia、and combination treatment with olanzapine for treatment-resistant or bipolar I depression. Unlabeled indications include: selective mutism、mild dementia-associated agitation in nonpsychotic patients、post-traumatic stress disorder (PTSD)、social anxiety disorder、chronic neuropathic pain、fibromyalgia、and Raynaud's phenomenon.、Use Classification: Animal Drugs -> FDA Approved Animal Drug Products (Green Book) -> Active Ingredients、Formulations、Preparations: Oral: Capsules: 10 mg (of fluoxetine)、Prozac Pulvules (Dista)、Sarafem Pulvules (Lilly)、20 mg (of fluoxetine)、40 mg (of fluoxetine)、Prozac Pulvules (Dista). Capsules、delayed-release (containing enteric-coated pellets): 90 mg (of Fluoxetine) Prozac Weekly (Dista). Solution: 20 mg (of fluoxetine) per 5 ml、Prozac (with alcohol 0.23%) (Dista). Tablets: 10 mg (of fluoxetine) Prozac (scored) (Dista)、Fluoxetine Hydrochloride Tablets (Par).、General Manufacturing Information: Commercially available as the hydrochloride salt.、(S)-Fluoxetine was synthesized from (S)-(-)-3-chloro-1-phenylpropanol by sequential reaction with sodium iodide、methylamine、sodium hydride、and 4-fluorobenzotrifluoride、(S)-Fluoxetine is dextrorotatory (+1.60) in methanol、but is levorotatory (-10.85) in water.、Preparation: ...B. B. Malloy、K. K. Schmiegel、DE 2500110、B. B. Malloy、US 4314081 (1975、1982 both to Lilly)。

技术档案

这个产品是什么

盐酸氟西汀是一种化工化合物，登记 CAS 号为 59333-67-4，分子式 C17H19ClF3NO（分子量 345.8）。

识别信息

登记 CAS 号：59333-67-4

其分子式 C17H19ClF3NO 由 17 个碳、19 个氢、1 个氯、3 个氟、1 个氮、1 个氧组成。

别名/同义词：盐酸氟西汀 · fluoxetine hydrochloride

常见问题

盐酸氟西汀的 CAS 号是多少？

盐酸氟西汀的 CAS 登记号为 59333-67-4。

盐酸氟西汀的分子式与分子量是多少？

分子式 C17H19ClF3NO，分子量 345.8。

盐酸氟西汀还有哪些别名？

别名/同义词：盐酸氟西汀、fluoxetine hydrochloride。

盐酸氟西汀的登记用途是什么？

PubChem 公开数据

盐酸氟西汀（CAS 59333-67-4）的独立参考数据，整理自公开化学数据库。

各数据库的登记标识

CAS Registry Number	59333-67-4
PubChem CID	62857
Molecular formula	C17H19ClF3NO
IUPAC name	N-methyl-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine;hydrochloride
UNII (FDA)	I9W7N6B1KJ

计算分子描述符

Molecular Weight	345.8
Hydrogen Bond Donor Count	2
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	345.1107264
Monoisotopic Mass	345.1107264
Topological Polar Surface Area	21.3
Heavy Atom Count	23

在册的理化数值

Melting Point	158.4-158.9 °C

在册的记载用途

同义词与商品名

FLUOXETINE HYDROCHLORIDE; 56296-78-7; Fluoxetine Hcl; Adofen; Fluctin; Fluoxeren; Lovan; Fontex; Foxetin; Fluox-Puren; Fluneurin; Reconcile; Flusol; Affectine; Deproxin; Digassim

已收录的法规名录

GHS notification summary	0.8% (1 / 131)

GHS 危害分类

GHS notification summary	0.8% (1 / 131)
Reported hazard statements	H302 (97.7%), H312 (13.7%), H318 (81.7%), H332 (14.5%), H361 (16.8%), H400 (93.1%)

This chemical does not meet GHS hazard criteria for 0.8% (1 of 131) of reports.

H302 (97.7%): Harmful if swallowed [Warning Acute toxicity, oral]

公开数据库对它的描述

fluoxetine hydrochloride · CAS 59333-67-4 · C17H19ClF3NO. UNII I9W7N6B1KJ. Melting Point: 158.4-158.9 °C.

物理形态与操作说明

数据来源：PubChem / Wikidata；与随货 COA 不一致时以 COA 为准。