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荧光素

CAS 2321-07-5C20H12O5MW 332.3

荧光素(CAS 2321-07-5):分子式 C20H12O5、分子量 332.3。

产品概览

CAS号2321-07-5
分子式C20H12O5
分子量332.3
熔点315
LogP3.4
应用领域Uses: Used as dye for cosmetics、cleansers、other household products、and vascular and ophthalmic diagnosis (may be in form of sodium salt)、Used as water indicator (detect leaks、pollution sources、and for sea rescues)、adsorption indicator、and dye intermediate、[HSDB] Used as analytical and clinical reagent、[Merck Index]、A presumptive reagent for dilute blood detection other than luminol is fluorescein.、Yellow dye for cosmetics、and other household products、tracing agent for water leaks、dye to detect water pollution sources、stic agent in ophthalmology (sodium salt)、chem int for dyes、As a marker for life saving at sea ...、and、detecting water leaks.、Dyeing seawater for spotting purposes、tracer to locate impurities in wells、dyeing silk and wool、indicator and reagent for bromine.、For more Uses (Complete) data for FLUORESCEIN (7 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >75、Consumption (g per capita、approx.) in Germany (2009): 0.000916、Calculated removal (%): 47.4、For diagnostic imaging. Primarily indicated in diagnostic fluorescein angiography or angioscopy of the fundus and of the iris vasculature.、Methods of Manufacturing: Condensation of resorcinol with phthalic anhydride in the presence of zinc chloride、By heating phthalic anhydride and resorcinol.、Impurities: 2-(2-4、dihydroxybenzoyl)benzoic acid、Phthalic acid、Resorcinol、U.S. Production: (1986) No Data、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#3868]、[US EPA、Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Spiro[isobenzofuran-1(3H)、9'-、U.S. Imports: (1983) 2.07X10+6、Acid Yellow 73、U.S. Exports: (1986) No Data、General Manufacturing Information: Spiro[isobenzofuran-1(3H)、9'-[9H]xanthen]-3-one、3'、6'-dihydroxy-: ACTIVE、Its diagnostic usefulness rests upon its fluorescence ... Appears readily in extracellular fluid and gains access only to viable cells ... Ulcerated areas ... stained green、foreign bodies ... surrounded by green ring、and loss of substance in conjunctiva ... indicated by yellow stain.、Color additives were initially regulated in the United States under the U.S. Department of Agriculture's (USDA) Bureau of Chemistry. In 1906、the Food and Drugs Act was passed by Congress、which prohibited the use of poisonous or deleterious colors in confectionery and the coloring or staining of food to conceal damage or inferiority. In 1927、responsibility of the Food and Drugs Act was transferred to FDA. Increasing government oversight、the Federal Food、Drug、and Cosmetic Act (FFDCA) was passed in 1938 and established the three following categories for colors: FD&C: colors used in foods、drugs and cosmetics、D&C: colors used in drugs and cosmetics when in contact with mucous membranes or ingested、and Ext. D&C: colors used in products applied externally.

应用领域

登记用途:Uses: Used as dye for cosmetics、cleansers、other household products、and vascular and ophthalmic diagnosis (may be in form of sodium salt)、Used as water indicator (detect leaks、pollution sources、and for sea rescues)、adsorption indicator、and dye intermediate、[HSDB] Used as analytical and clinical reagent、[Merck Index]、A presumptive reagent for dilute blood detection other than luminol is fluorescein.、Yellow dye for cosmetics、and other household products、tracing agent for water leaks、dye to detect water pollution sources、stic agent in ophthalmology (sodium salt)、chem int for dyes、As a marker for life saving at sea ...、and、detecting water leaks.、Dyeing seawater for spotting purposes、tracer to locate impurities in wells、dyeing silk and wool、indicator and reagent for bromine.、For more Uses (Complete) data for FLUORESCEIN (7 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >75、Consumption (g per capita、approx.) in Germany (2009): 0.000916、Calculated removal (%): 47.4、For diagnostic imaging. Primarily indicated in diagnostic fluorescein angiography or angioscopy of the fundus and of the iris vasculature.、Methods of Manufacturing: Condensation of resorcinol with phthalic anhydride in the presence of zinc chloride、By heating phthalic anhydride and resorcinol.、Impurities: 2-(2-4、dihydroxybenzoyl)benzoic acid、Phthalic acid、Resorcinol、U.S. Production: (1986) No Data、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#3868]、[US EPA、Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Spiro[isobenzofuran-1(3H)、9'-、U.S. Imports: (1983) 2.07X10+6、Acid Yellow 73、U.S. Exports: (1986) No Data、General Manufacturing Information: Spiro[isobenzofuran-1(3H)、9'-[9H]xanthen]-3-one、3'、6'-dihydroxy-: ACTIVE、Its diagnostic usefulness rests upon its fluorescence ... Appears readily in extracellular fluid and gains access only to viable cells ... Ulcerated areas ... stained green、foreign bodies ... surrounded by green ring、and loss of substance in conjunctiva ... indicated by yellow stain.、Color additives were initially regulated in the United States under the U.S. Department of Agriculture's (USDA) Bureau of Chemistry. In 1906、the Food and Drugs Act was passed by Congress、which prohibited the use of poisonous or deleterious colors in confectionery and the coloring or staining of food to conceal damage or inferiority. In 1927、responsibility of the Food and Drugs Act was transferred to FDA. Increasing government oversight、the Federal Food、Drug、and Cosmetic Act (FFDCA) was passed in 1938 and established the three following categories for colors: FD&C: colors used in foods、drugs and cosmetics、D&C: colors used in drugs and cosmetics when in contact with mucous membranes or ingested、and Ext. D&C: colors used in products applied externally.。

技术档案

这个产品是什么

荧光素 是一种化工化合物,登记 CAS 号为 2321-07-5,分子式 C20H12O5(分子量 332.3)。

识别信息

登记 CAS 号:2321-07-5

其分子式 C20H12O5 由 20 个碳、12 个氢、5 个氧 组成。

别名/同义词:荧光素 · Fluorescein

常见问题

荧光素 的 CAS 号是多少?

荧光素 的 CAS 登记号为 2321-07-5。

荧光素 的分子式与分子量是多少?

分子式 C20H12O5,分子量 332.3。

荧光素 还有哪些别名?

别名/同义词:荧光素、Fluorescein。

荧光素 的登记用途是什么?

登记用途:Uses: Used as dye for cosmetics、cleansers、other household products、and vascular and ophthalmic diagnosis (may be in form of sodium salt)、Used as water indicator (detect leaks、pollution sources、and for sea rescues)、adsorption indicator、and dye intermediate、[HSDB] Used as analytical and clinical reagent、[Merck Index]、A presumptive reagent for dilute blood detection other than luminol is fluorescein.、Yellow dye for cosmetics、and other household products、tracing agent for water leaks、dye to detect water pollution sources、stic agent in ophthalmology (sodium salt)、chem int for dyes、As a marker for life saving at sea ...、and、detecting water leaks.、Dyeing seawater for spotting purposes、tracer to locate impurities in wells、dyeing silk and wool、indicator and reagent for bromine.、For more Uses (Complete) data for FLUORESCEIN (7 total)、please visit the HSDB record page.、Use (kg、approx.) in Germany (2009): >75、Consumption (g per capita、approx.) in Germany (2009): 0.000916、Calculated removal (%): 47.4、For diagnostic imaging. Primarily indicated in diagnostic fluorescein angiography or angioscopy of the fundus and of the iris vasculature.、Methods of Manufacturing: Condensation of resorcinol with phthalic anhydride in the presence of zinc chloride、By heating phthalic anhydride and resorcinol.、Impurities: 2-(2-4、dihydroxybenzoyl)benzoic acid、Phthalic acid、Resorcinol、U.S. Production: (1986) No Data、Production volumes for non-confidential chemicals reported under the Inventory Update Rule. [Table#3868]、[US EPA、Non-confidential Production Volume Information Submitted by Companies for Chemicals Under the 1986-2002 Inventory Update Rule (IUR). Spiro[isobenzofuran-1(3H)、9'-、U.S. Imports: (1983) 2.07X10+6、Acid Yellow 73、U.S. Exports: (1986) No Data、General Manufacturing Information: Spiro[isobenzofuran-1(3H)、9'-[9H]xanthen]-3-one、3'、6'-dihydroxy-: ACTIVE、Its diagnostic usefulness rests upon its fluorescence ... Appears readily in extracellular fluid and gains access only to viable cells ... Ulcerated areas ... stained green、foreign bodies ... surrounded by green ring、and loss of substance in conjunctiva ... indicated by yellow stain.、Color additives were initially regulated in the United States under the U.S. Department of Agriculture's (USDA) Bureau of Chemistry. In 1906、the Food and Drugs Act was passed by Congress、which prohibited the use of poisonous or deleterious colors in confectionery and the coloring or staining of food to conceal damage or inferiority. In 1927、responsibility of the Food and Drugs Act was transferred to FDA. Increasing government oversight、the Federal Food、Drug、and Cosmetic Act (FFDCA) was passed in 1938 and established the three following categories for colors: FD&C: colors used in foods、drugs and cosmetics、D&C: colors used in drugs and cosmetics when in contact with mucous membranes or ingested、and Ext. D&C: colors used in products applied externally.。

PubChem 公开数据

荧光素(CAS 2321-07-5)的独立参考数据,整理自公开化学数据库。

各数据库的登记标识

CAS 号2321-07-5
PubChem CID16850
分子式C20H12O5
IUPAC 名称3',6'-dihydroxyspiro[2-benzofuran-3,9'-xanthene]-1-one
UNII(FDA)TPY09G7XIR

计算分子描述符

Molecular Weight332.3
XLogP33.4
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count0
Exact Mass332.06847348
Monoisotopic Mass332.06847348
Topological Polar Surface Area76
Heavy Atom Count25

在册的理化数值

Melting Point315
Melting Point315 °C (decomposes)
Melting Point315 °C
Solubility600
SolubilityIn water, 50 mg/L at 20 °C
Solubility2.55e-02 g/L
LogP3.4
LogP4.3
Color Additive Status74.1707
Color Additive Status74.2707

同义词与商品名

荧光素; 2321-07-5;溶剂黄94;间苯二酚酞;黄色荧光素;荧光素;荧光素酸; 3,6-氟二醇; D&C 黄7号; 3',6'-二羟基荧烷;日本黄201; D和C黄7号; C.I.溶剂黄94;皂黄F;希达酸荧光素;黄7号

已收录的法规名录

法规与食品接触FDA Regulatory Status of Color Additives: Drugs, Cosmetics
GHS 通报统计3.4% (13 / 383)

GHS 危害分类

GHS 通报统计3.4% (13 / 383)
已通报的危害声明H302 (13.6%), H319 (96.6%)

公开数据库对它的描述

荧光素 · CAS 2321-07-5 · C20H12O5. UNII TPY09G7XIR. Melting Point: 315; Melting Point: 315 °C (decomposes); Melting Point: 315 °C.

数据来源:PubChem / Wikidata;与随货 COA 不一致时以 COA 为准。

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English page: Fluorescein

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