氟芬醋

Description

Flufenacet · CAS 142459-58-3 · C14H13F4N3O2S. UNII OL44PP5145. Melting Point: 76-79 °C; Density: 1.312 g/mL; Vapor Pressure: 0.00000067 [mmHg].

Identification

CAS Registry Number	142459-58-3
PubChem CID	86429
Molecular formula	C14H13F4N3O2S
IUPAC name	N-(4-fluorophenyl)-N-propan-2-yl-2-[[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy]acetamide
UNII (FDA)	OL44PP5145

Computed Descriptors

Molecular Weight	363.33
XLogP3	3.6
Hydrogen Bond Donor Count	0
Hydrogen Bond Acceptor Count	9
Rotatable Bond Count	5
Exact Mass	363.06646049
Monoisotopic Mass	363.06646049
Topological Polar Surface Area	83.6
Heavy Atom Count	24
Formal Charge	0

Physical & Chemical Properties

Melting Point	76-79 °C
Density	1.312 g/mL
Vapor Pressure	0.00000067 [mmHg]
Vapor Pressure	6.75X10-7 mm Hg at 20 °C (6.0X10-2 mPa at 20 °C)
LogP	Kow = 1600 at 24 °C (log Kow = 3.20)
LogP	3.19

Physical description & handling notes

• White to tan solid; [Merck Index] Light beige powder; [MSDSonline]
• White to tan solid
• White solid
• Mercaptan-like odor
• Decomposes
• Solubility in organic solvents (g/L at 20 °C): n-hexane - 8.7; toluene - >200; dichloromethane - >200; 2-propanol - 170; 1-octanol - 88; polyethylene glycol - 74; acetone - >200; dimethylformamide - >200; acetonitrile - >200; dimethylsulfoxide - >200

GHS Hazard Classification

Reported hazard statements	H302, H317, H373, H400, H410, H335, H351

Documented Uses

• Used as pre-emergence herbicide to control annual grasses and broadleaf weeds in corn and soybeans; [HSDB]
• Pre-plant-incorporated, pre-plant-surface, pre-emergence in maize and soya beans, pre-planting in tomatoes, pre-emergence in potatoes and sunflowers, and post-emergence in maize, wheat and rice.
• Flufenacet is applied to the soil surface or incorporated preemergence in field corn, corn grown for silage, or soybeans to control certain annual grasses and broadleaf weeds.
• Flufenacet can be made by reaction of equivalent quantities of 2-methylsulfonyl-5-trifluoromethyl-1,3,4-thiadiazole with 2-hydroxy-[N-(4-fluoropheny)-N-isopropyl] acetamide in the presence of sodium hydroxide in acetone at 0 - 5 °C.
• FOE 5043 DF Herbicide formulation applied by ground only at 12 to 21 ounces per acre to corn and 7 to 12 ounces per acre to soybeans. Axiom DF Herbicide formulation applied by ground only at 13 to 23 ounces per acre to corn and 7 to 13 ounces per acre to soybeans.
• A rat metab study showed that radiolabeled flufenacet was rapidly absorbed & metabolized by both sexes. Urine was the major route of excretion at all dose levels & smaller amounts were excreted via the feces. A max of 7% of admin dose was found in the tissue & residual carcass. 39 metabolites were detected in excreta & 23 were positively identified.

Synonyms

Flufenacet; 142459-58-3; Fluthiamide; Thiafluamide; Fluthiamid; Foe 5043; DTXSID2032552; FOE-5043; OL44PP5145; N-(4-Fluorophenyl)-N-(1-methylethyl)-2-((5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)oxy)acetamide; BAY FOE-5043; DTXCID0012552; CHEBI:81920; N-(4-fluorophenyl)-N-(propan-2-yl)-2-{[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]oxy}acetamide; 4'-FLUORO-N-ISOPROPYL-2-(5-(TRIFLUOROMETHYL)-1,3,4-THIADIAZOL-2-YLOXY)ACETANILIDE; N-ISOPROPYL-(5-TRIFLUOROMETHYL-1,3,4-THIADIAZOL-2-YL)-(4'-FLUOROOXYACETANILIDE)

Frequently Asked Questions

What are the CAS number and molecular formula of Flufenacet?

CAS 142459-58-3; molecular formula C14H13F4N3O2S; molecular weight — g/mol.

What other names is Flufenacet known by?

Flufenacet, 142459-58-3, Fluthiamide, Thiafluamide, Fluthiamid, Foe 5043.

Is Flufenacet classified as hazardous?

Hazard statements reported: H302, H317, H373, H400, H410.

What are the key physical properties of Flufenacet?

Melting Point: 76-79 °C; Density: 1.312 g/mL; Vapor Pressure: 0.00000067 [mmHg]; Vapor Pressure: 6.75X10-7 mm Hg at 20 °C (6.0X10-2 mPa at 20 °C).

Facts on this page are taken from PubChem (US National Library of Medicine) and Wikidata. Grade-specific data — assay, moisture, particle size, packaging, shelf life — is issued per batch on the COA and is not published here.