Ezetimibe (CAS 163222-33-1) — formula C24H21F2NO3, molecular weight 409.4; category chemical intermediates.
Ezetimibe (CAS 163222-33-1) is a chemical raw material in the chemical intermediates category. Its molecular formula C24H21F2NO3 comprises 24 C, 21 H, 2 F, 1 N, 3 O atoms. Its molecular weight is about 409.4. Reported physicochemical data: melting point around 163°C, LogP about 4.5. As a sourcing and distribution partner we help locate and compare this item across domestic and cross-border channels, arranging samples and batch orders with full COA and compliance files.
| CAS Number | 163222-33-1 |
|---|---|
| Molecular Formula | C24H21F2NO3 |
| Molecular Weight | 409.4 |
| Melting Point | 163°C |
| LogP | 4.5 |
| Applications | THERAP CAT: Antilipemic, Medication, So far only one cholesterol absorption inhibitor has reached the market: Ezetimibe. Although the detailed mechanism of action is not yet quite clear, /Ezetimibe/ inhibits the intestinal absorption of cholesterol and as a consequence lowers total plasma cholesterol, Use (kg, approx.) in Germany (2009): >1000 |
| Category | Chemical Intermediates |
Documented applications: THERAP CAT: Antilipemic, Medication, So far only one cholesterol absorption inhibitor has reached the market: Ezetimibe. Although the detailed mechanism of action is not yet quite clear, /Ezetimibe/ inhibits the intestinal absorption of cholesterol and as a consequence lowers total plasma cholesterol, Use (kg, approx.) in Germany (2009): >1000.
Ezetimibe is a chemical intermediate compound with CAS registry number 163222-33-1 and molecular formula C24H21F2NO3 (molecular weight 409.4), belonging to the chemical intermediates segment of chemical raw materials.
CAS number: 163222-33-1
Its molecular formula C24H21F2NO3 comprises 24 C, 21 H, 2 F, 1 N, 3 O atoms.
Also known as: Ezetimibe · 依折麦布
Category: chemical intermediates
The CAS registry number of Ezetimibe is 163222-33-1.
Molecular formula C24H21F2NO3, molecular weight 409.4.
It is also registered under: Ezetimibe, 依折麦布.
Recorded applications: THERAP CAT: Antilipemic, Medication, So far only one cholesterol absorption inhibitor has reached the market: Ezetimibe. Although the detailed mechanism of action is not yet quite clear, /Ezetimibe/ inhibits the intestinal absorption of cholesterol and as a consequence lowers total plasma cholesterol, Use (kg, approx.) in Germany (2009): >1000.
Category: Chemical Intermediates.
Packaging is agreed per order, from lab-scale packs to bulk, and confirmed with each order rather than fixed on the page. A Certificate of Analysis (COA) ships with every batch and MSDS is available; where the end use carries a regulatory limit (food contact, pharmaceutical or cosmetic), state the standard at enquiry and the grade is set against it.
Independent reference data for Ezetimibe (CAS 163222-33-1), compiled from public chemistry databases.
| CAS Registry Number | 163222-33-1 |
|---|---|
| PubChem CID | 150311 |
| Molecular formula | C24H21F2NO3 |
| IUPAC name | (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one |
| UNII (FDA) | EOR26LQQ24 |
| Molecular Weight | 409.4 |
|---|---|
| XLogP3 | 4 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 6 |
| Exact Mass | 409.14894986 |
| Monoisotopic Mass | 409.14894986 |
| Topological Polar Surface Area | 60.8 |
| Heavy Atom Count | 30 |
| Melting Point | 163°C |
|---|---|
| Melting Point | 164-166 °C |
| Solubility | 8.46e-03 g/L |
| LogP | 4.5 |
| LogP | 3.64 |
Ezetimibe; 163222-33-1; Zetia; Ezetrol; Ezedoc; (3R,4S)-1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)azetidin-2-one; Sch 58235; SCH-58235; SCH58235; ezetimiba; EOR26LQQ24; ezetimibum; DTXSID1044223; 2-Azetidinone, 1-(4-fluorophenyl)-3-[(3S)-3-(4-fluorophenyl)-3-hydroxypropyl]-4-(4-hydroxyphenyl)-, (3R,4S)-; MK0653; NSC-758923
| Reported hazard statements | H410 (85%) |
|---|
H410 (85%): Very toxic to aquatic life with long lasting effects [Warning Hazardous to the aquatic environment, long-term hazard]
P273, P391, and P501 (click each P-code to see the statement)
N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline · CAS 163222-33-1 · C24H21F2NO3. UNII EOR26LQQ24. Melting Point: 163°C; Melting Point: 164-166 °C; Solubility: 8.46e-03 g/L.
Source: PubChem / Wikidata; the batch COA governs where values differ.
Supplier: Jinan Shenghe Chemical Co., Ltd.
中文页面: 依折麦布